PLASMA CATECHOLAMINE RESPONSES TO DYNAMIC EXERCISE IN PATIENTS WITH CORONARY ARTERY DISEASE : The Relationship between Sympathetic Activity and Systolic Blood Pressure and Exercise-induced Ventricular Arrhythmias
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概要
- 論文の詳細を見る
In order to investigate the relationship between sympathetic activity and postexercise systolic blood pressure (SBP) and exercise-induced ventricular arrhythmias in patients with coronary artery disease (CAD), we studied 38 patients and 9 normal subjects who underwent treadmill testing. Peak pressure-rate product was similar in the 2 groups. The plasma concentrations of norepinephrine and epinephrine at rest and immediately after exercise were significantly higher in patients with CAD compared with normal subjects (norepinephrine at rest, p<0.01; norepinephrine immediately after exercise, p<0.05; epinephrine at rest, p<0.05; epinephrine immediately after exercise, p<0.05). The level of norepinephrine immediately after exercise was significantly higher in 15 patients with a postexercise SBP increase than in 23 patients without that SBP change (p<0.05), whereas the level of epinephrine was similar in the 2 groups. The level of epinephrine immediately after exercise was significantly higher in 10 patients with exercise-induced premature ventricular contractions than in 28 patients without those arrhythmias (p<0.05), whereas the level of norepinephrine was similar in the 2 groups. We conclude that a postexercise SBP increase is related to the augmentation of sympathoneural activity and that exercise-induced ventricular arrhythmias are related to the augmentation of sympathoadrenal activity.
- 社団法人日本循環器学会の論文
- 1992-11-20
著者
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Muratani H
Department Of Clinical Pharmacology And Therapeutics Tohoku University
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Miyakoda Hiroyuki
Department Of Bioscience National Cardiovascular Center
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MATSUMOTO Tatsuhiko
The First Department of Internal Medicine, Gunma University School of Medicine
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Kinugawa Toru
Kitano Hospital
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Hoshio Akira
First Department of Internal Medicine, Tottori University
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Miyakoda Hiroyuki
The First Department of Internal Medicine, Tottori University School of Medicine
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Noguchi Noriyasu
The First Department of Internal Medicine, Tottori University School of Medicine
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Kinugawa Toru
The First Department of Internal Medicine, Tottori University School of Medicine
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Hoshio Akira
The First Department of Internal Medicine, Tottori University School of Medicine
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Kotake Hiroshi
The First Department of Internal Medicine, Tottori University School of Medicine
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Mashiba Hiroto
The First Department of Internal Medicine, Tottori University School of Medicine
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KITAMURA HIDEYUKI
The First Department of Internal Medicine, Tottori University School of Medicine
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OGINO KAZUHIDE
The First Department of Internal Medicine, Tottori University School of Medicine
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Matsuura Takashi
Division Of Regenerative Medicine And Therapeutics Tottori University Graduate School Of Medical Sci
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HIROE Koh
First Department of Internal Medicine, Tottori University Faculty of Medicine
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Kinugawa Tooru
Kitano Hospital The Tazuke Kofukai Medical Research Institute
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Matsumoto Tatsuhiko
Division Of Regenerative Medicine And Therapeutics Tottori University Graduate School Of Medical Sci
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Hoshio Akira
First Department Of Internal Medicine Tottori University
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Miyakoda Hiroyuki
The First Department Of Internal Medicine Tottori University School Of Medicine
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Hiroe Koh
First Department Of Internal Medicine Tottori University Faculty Of Medicine
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Kinugawa Toru
Dept. Of Internal Medicine Tottori Univ.
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Hoshio Akira
The First Department Of Internal Medicine Tottori University School Of Medicine
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Hoshio Akira
First Department Of Internal Medicine Tottori University School Of Medicine
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Kotake Hiroshi
The First Department Of Internal Medicine Tottori University School Of Medicine
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Kitamura Hideyuki
The First Department Of Internal Medicine Tottori University School Of Medicine
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Matsumoto Tatsuhiko
The First Department Of Internal Medicine Gunma University Faculty Of Medicine
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Noguchi Noriyasu
The First Department Of Internal Medicine Tottori University School Of Medicine
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Mashiba Hiroto
The First Department Of Internal Medicine Facullty Of Medicine Tottori University
-
Mashiba Hiroto
1st Department Of Internal Medicine Tottori University School Of Medicine
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Matsuura Takashi
Division Of Regenerative Medicine And Therapeutics Department Of Genetic Medicine And Regenerative T
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Kotake Hiroshi
First Department Of Internal Medicine Tottori University School Of Medicine
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Kotake Hiroshi
Dept Of Internal Medicine Tottori Univ.
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