USEFULNESS OF INTRAVENOUS DIPYRIDAMOLE COMBINED WITH PACING STRESS FOR DETECTION OF MYOCARDIAL ISCHEMIA IN CORONARY ARTERY DISEASE
スポンサーリンク
概要
- 論文の詳細を見る
In order to establish a more clinically useful diagnostic method to detect myocardial ischemia, a stress test of 0.56 mg/kg of intravenous dipyridamole (D), an atrial pacing (P) and the combination of both (D + P) were administered to 14 patients with significant coronary stenosis and 8 patients with normal coronary arteriogram. The effects on regional coronary hemodynamics and myocardial metabolism were subsequently studied. Treadmill exercise tests in 15 patients and thallium-201 exercise myocardial scintigraphy in 14 patients were also performed at another time. When the uptake ratio of myocardial lactate less than 0% was sued as an indicator of myocardial ischemia, 100% (12/12) of sensitivity and 100% (6/6) of specificity were obtained with (D+P)-test in diagnosis of significant coronary stenosis and its sensitivity was significantly higher than that with P-test (43%) or with D-test (31%). Even though sensitivity and specificity of exercise electrocardiogram (70% and 50%) or thallium-201 exercise myocardial scintigram (88% and 80%) in diagnosis of coronary stenosis were not significantly lower than those of (D+P)-test respectively, myocardial ischemia could also be detected with (D+P)-test in two patients at the region perfused by the infarct-related artery, which had not been detected by thallium-201 exercise myocardial imaging. We conclude, (D+P)-test combined with investigation of myocardial lactate metabolism is quite useful to detect myocardial ischemia.
- 社団法人日本循環器学会の論文
- 1986-10-20
著者
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Fukuzaki Hisashi
The First Department Of Internal Medicine Kobe University School Of Medicine
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Kobayashi Katsuya
The First Department Of Internal Medicine Kobe University School Of Medicine
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FUKUZAKI Hisashi
三木市民院循環器内科
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Fukuzaki Hisashi
Department Of Thoracie Srugery Osaka Medical College
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Fukuzaki Hisashi
Dept Of Intern Med. Div. I Kobe Univ. School Of Med.
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KURIMOTO YASUYUKI
The First Department of Internal Medicine, Kobe University School of Medicine
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Fukuzaki Hisashi
The First Department Of Internal Medicine Kobe University
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Kurimoto Yasuyuki
The First Department Of Internal Medicine Kobe University School Of Medicine
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Fukuzaki Hisashi
Dept. Of Int. Med. Div1 Kobe Univ.
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Fukuzaki Hisashi
1st Dep. Of Internal Med. Kobe Univ.
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Fukuzaki Hisashi
Department Of Thoracic Surgery Osaka Medical College
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Kobayashi K
The First Department Of Internal Medicine Kobe University School Of Medicine
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