ASSESSMENT OF LEFT VENTRICULAR FUNCTION IN ISCHEMIC HEART DISEASE : The Relation between Pressure Decay during the Isovolumic Relaxation Phase and Regional Wall Motion Abnormality

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概要

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• We examine whether regional wall motion abnormality (RWMA) could contribute to the slowed relaxation rate of the left ventricle (LV) in patients with coronary artery disease (CADpts). Simultaneous observations were made on the time constant (Tc) of the isovolumic pressure decay and left ventriculography at the control period and after right atrial pacing. Subsequently, the subjects investigated were divided into 3 groups, i.e. normal subjects (Group I, n=8), CADpts with normal wall motion during the control period (Group II n=21), and CADpts with RWMA during the control period (Group III, n=28). The latter two groups were further divided into two subgroups according to the presence (Group IIa and IIIa) or absence (Group IIb and IIIb) of pacing-induced RWMA. We measured Tc by a method of exponential analysis that could estimate the asymptote. During the control period, Tc was significantly prolonged in Group III (82 ± 26 msec) than that in Group I (60 ± 6 msec) and Group II (63 ± 12 msec). Tc was prolonged in proportion to the extent of RWMA during the control period. Immediately after right atrial pacing, Tc was markedly prolonged in Group IIa (from 61 ± 12 to 90 20 msec, p < 0.001) and in Group IIIa (from 73 ± 26 to 95 ± 34 msec, p < 0.001). The post-pacing prolongation of Tc was closely correlated with the extent of post-pacing RWMA. From these results, it is postulated that RWMA may play an important role as a causes of the altered LV relaxation in CADpts.

• 社団法人日本循環器学会の論文
• 1984-09-20

著者

• Fujitani Kazuhiro

  The First Department Of Internal Medicine Hyogo College Of Medicine

• Fujitani Kazuo

  The First Department Of Internal Medicine Hyogo College Of Medicine

• Toda Chuichi

  The First Dept of Int Med Kobe University School of Medicine

• Fukuzaki Hisashi

  The First Department Of Internal Medicine Kobe University School Of Medicine

• Takeuchi Motoshi

  The First Department of Internal Medcine,Kobe University School of Medicine

• Bai Hong-Tai

  The First Department of Internal Medicine, Kobe University School of Medicine

• KUROGANE KEIJI

  The First Department of lnternal Medicine, Kobe University School of Medicine

• Fukuzaki Hisashi

  The First Department Of Internal Medicine Kobe University

• Takeuchi Motoshi

  The First Department Of Internal Medicine Kobe University School Of Medicine Kobe

• Takeuchi Motoshi

  Department Of Cardiology Himeji Cardiovascular Center

• Fujitani Kazuhiro

  The First Department Of Internal Medicine Hiroshima University School Of Medicine

• Fujitani Kazuo

  Department Of Internal Medicine Devision I Kobe University School Of Medicine

• Bai Hong-tai

  The First Department Of Internal Medicine Kobe University School Of Medicine

• Kurogane Keiji

  The First Department Of Internal Medicine Kobe University School Of Medicine

• Fukuzaki Hisashi

  1st Dep. Of Internal Med. Kobe Univ.

• Toda Chuichi

  The First Department Of Internal Medicine Kobe University School Of Medicine

• FUJIWARA Katsuaki

  Rokko Hospital

• Fujitani Kazuhiro

  Department Of Internal Medicine Division I.. Kobe University School Of Medicine

• Fujitani Kazuhiro

  Department Of Internal Medicine Division I. Kobe University School Of Medicine

• Kurogane Keiji

  First Department Of Internal Medicine Kobe University School Of Medicine

• Fujiwara Katsuaki

  Kobe University Department Of Medicine Division I

• Fujiwara Katsuaki

  The First Depertment Of Internal Medicine Kobe University Scbool Of Medicine.

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