Interferon Treatment for Dilated Cardiomyopathy and Striated Myopathy Associated With Hepatitis C Virus Infection Based on Serial Measurements of Serum Concentrations of Cardiac Troponin T
スポンサーリンク
概要
- 論文の詳細を見る
The present authors recently suggested, on the basis of studies using polymerase chain reaction(PCR), that hepatitis C virus(HCV) infection is involved in the etiology or pathogenesis of cardiomyopathic disorders. They have also reported that the serum concentration of cardiac troponin T is an indicator of ongoing myocyte degeneration in patients with dilated cardiomyopathy(DCM) and hypothesized that its serial measurement may be a marker of therapeutic efficacy. This is the first case report of DCM and striated myopathy, associated with HCV infection, treated with interferon therapy guided by monitoring of serial serum concentrations of cardiac troponin T. Positive-plus strands of HCV RNA were found in the patient's myocardium, as well as plus and minus strands in the quadriceps muscle specimens. Serum levels of creatine kinase(CK), CK-MB and cardiac troponin T fell as serum HCV titers decreased during treatment with interferon, whereas conventional treatment of heart failure had no effect. Monitoring of serial serum concentrations of cardiac troponin T may allow the earlier diagnosis and treatment of patients with HCV-associated cardiomyopathy and improve their clinical course.
- 社団法人日本循環器学会の論文
- 2000-03-20
著者
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TANIGUCHI Ryoji
Division of Cardiology, Hyogo Prefectural, Amagasaki Hospital
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Matsumori Akira
同志社大学 生命医科学部
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Matsumori Akira
Department Of Cardiovascular Medicine Kyoto University Graduate School Of Medicine
-
Sasayama S
Department Of Life And Medical Science Doshisha University Kyotanabe & Daijukai Hospital
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Sasayama Shigetake
浜松労災病院
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Matsumori A
Department Of Cardiovascular Medicine Kyoto University Graduate School Of Medicine
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Yamada Tasuku
Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University
-
Takatsu Yoshiki
Division of cardiology, Hyogo Prefectural Amagasaki Hospital
-
Sasayama Shigetake
Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine
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Sasayama Shigetake
The Department Of Cardiology Hyogo Prefectural Amagasaki Hospital
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Tanada Yohei
兵庫県立尼崎病院 循環器内科
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Sato Yukihito
Department Of Cardiovascular Medicine Hyogo Prefectural Amagasaki Hospital
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Sato Yukihito
Division Of Cardiovascular Medicine Department Of Internal Medicine Hyogo Prefectural Amagasaki Hosp
-
Saijyo Sayaka
Department Of Cardiology Hyogo Prefectural Amagasaki Hospital
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Yamada Tasuku
Department Of Cardiovascular Medicine Kyoto University Graduate School Of Medicine
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Taniguchi Ryoji
Department Of Cardiovascular Medicine Kyoto University
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Taniguchi Ryoji
Department Of Cardiology Hyogo Prefectural Amagasaki Hospital
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Sawada Shigeo
Department Of Cardiology Doshisha University
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Sasayama Shigetake
The Third Division Of Medicine Kyoto University
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Sasayama Shigetake
Hamamatsu Rosai Hospital
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Kataoka Kazuaki
Hyogp Prefectural Amagasaki Hospital
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YAMADA Tasuku
Division of Cardiology, Department of Internal Medicine, Hyogo Prefectural Amagasaki Hospital
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Takatsu Yoshiki
Division Of Cardiology Hyogo Prefectural Amagasaki Hospital
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Kataoka Kazuaki
Division Of Endocrinology And Metabolism Department Of Internal Medicine Hyogo Prefectural Amagasaki
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Marui Akira
Department Of Cardiovascular Surgery Kyoto University Graduate School Of Medicine
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Sasayama Shigetake
Department Of Cardiovascular Medicine Graduate School Of Medicine Kyoto University
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Sasayama Shigetake
Division Of Medicine Hamamatsu Rosai Hospital Shizuoka
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Mimura Rokuro
Division of Pathology, Hyogo Prefectural Amagasaki Hospital
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Sasayama Shigetake
Department Of Cardiology Hyogo Prefectural Amagasaki Hospital
-
Mimura Rokuro
Division Of Nephrology Department Of Internal Medicine Hyogo Prefectural Amagasaki Hospital
-
Mimura Rokuro
Division Of Pathology Hyogo Prefectural Amagasaki Hospital
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Sasayama Shigetake
Department Of Cardiology Doshisha University
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Matsumori Akira
Department Of Cardiology Kyoto University
-
Saijyo Sayaka
The Department Of Cardiology Hyogo Prefectural Amagasaki Hospital
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Murashige Akihiro
Department Of Cardiology Kyoto University
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Matsumori A
The Third Division Department Of Internal Medicine Faculty Of Medicine Kyoto University
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Matsumori Akira
Department Of Cardiovascular Medicine Graduate School Of Medicine Kyoto University
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Taniguchi Ryoji
Division Of Cardiology Hyogo Prefectural Amagasaki Hospital
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