Delayed Onset of Pulmonary Hypertension Associated With an Appetite Suppressant, Mazindol : A Case Report

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概要

• 論文の詳細を見る

• The use of the appetite suppressant agents aminorex and fenfluramine derivatives has been reported as a risk factor for the development of pulmonary hypertension. A 29-year-old female developed pulmonary hypertension suspected to be due to an amphetamine-like appetite suppressant agent, mazindol ((±)-5-(p-chlorophenyl)-2,5-dihydro-3H-imidazo [2,1-a] isoindol-5-ol). She was admitted to Sapporo Medical University Hospital with dyspnea due to severe pulmonary hypertension. Twelve months prior to admission, she had taken mazindol continuously for a period of 10 weeks. As yet, her pulmonary hypertension has not completely improved. This is the first reported case of mazindol-associated pulmonary hypertension, which developed after a long latent interval, and it suggests that mazindol is also a risk factor for the development of pulmonary hypertension, making long-term follow-up necessary for patients taking this anorectic agent.

• 社団法人日本循環器学会の論文
• 2000-02-20

著者

• Tsuchihashi Kazufumi

  Second Department of Internal Medicine, Sapporo Medical University School of Medicine

• Shimamoto Kazuaki

  Second Department of Internal Medicine, Sapporo Medical University School of Medicine

• HYAKKOKU Masaya

  Second Department of Internal Medicine, Sapporo Medical University School of Medicine

• Nishizato Kimio

  Second Department of Internal Medicine, Sapporo Medical University School of Medicine

• SHIMAMOTO Kazuaki

  Committee for Epidemiology and Clinical Management of Atherosclerosis

• Tsuchihashi Kazufumi

  Second Department Of Internal Medicine Sapporo Medical University School Of Medicine

• HAGIWARA Makoto

  Second Department of Internal Medicine, Sapporo Medical University School of Medicine

• Tsuchida Akihito

  Second Department of Internal Medicine, Sapporo Medical University School of Medicine

• Asai Tateki

  Second Department of Internal Medicine, Sapporo Medical University School of Medicine

• Nozawa Yukinaga

  Second Department of Internal Medicine, Sapporo Medical University School of Medicine

• Asai Tateki

  Second Department Of Internal Medicine Sapporo Medical University School Of Medicine

• Nishizato Kimio

  Second Department Of Internal Medicine Sapporo Medical University School Of Medicine

• Nishisato Kimio

  Second Department Of Internal Medicine Sapporo Medical University School Of Medicine

• Hagiwara Makoto

  Second Department Of Internal Medicine Sapporo Medical University School Of Medicine

• Hyakkoku Masaya

  Second Department Of Internal Medicine Sapporo Medical University School Of Medicine

• Nozawa Yukinaga

  Second Department Of Internal Medicine Sapporo Medical University School Of Medicine

• Tsuchida Akihito

  Second Department Of Internal Medicine Sapporo Medical University

• Tsuchida Akihito

  Second Department Of Internal Medicine Sapporo Medical University School Of Medicine

• Shimamoto Kazuaki

  Second Department Of Internal Medicine (cardiovascular Medicine) Sapporo Medical University School O

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