Comparison of Long-Term Clinical Outcome After Sirolimus-Eluting Stent Implantation in Patients With and Without Hemodialysis
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概要
- 論文の詳細を見る
Poor clinical outcomes for hemodialysis (HD) patients compared to non-HD patients after coronary intervention have been reported. Although coronary intervention using sirolimus-eluting stents (SESs) might be expected to reduce restenosis in HD patients, little is known about the efficacy of the SESs. The purpose of the present study was to compare the clinical and angiographic outcomes of HD patients with non-HD patients after SES implantation. The study population consisted of 170 consecutive patients (234 lesions) who had undergone successful coronary SES implantation. The patients were classified into 2 groups, an HD group (18 patients, 27 lesions) and a non-HD group (152 patients, 207 lesions). The incidence of any clinical event was significantly higher in the HD group than in the non-HD group (50.0% versus 12.5%, P < 0.0001). Target lesion revascularization was necessary in 6 patients (33.3%) in the HD group and in 7 patients (4.6%) in the non-HD group (P < 0.0001). The Cox proportional-hazards regression model on cardiac events identified HD patients (P = 0.0301, hazard ratio = 2.704) as an explanatory factor. Moreover, the Cox proportional-hazards regression model on target lesion revascularization identified HD (P = 0.0004, hazard ratio = 6.921) and in-stent re-stenosis lesion (P = 0.0293, hazard ratio = 3.323) as explanatory factors. The present study suggests that compared with non-HD patients, HD patients with coronary artery disease treated by SESs have a poorer clinical outcome.
- インターナショナル・ハート・ジャーナル刊行会の論文
著者
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Shimamoto Kazuaki
Second Department of Internal Medicine, Sapporo Medical University School of Medicine
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Maeda Takuto
Second Department of Internal Medicine, Sapporo Medical University
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Maeda Takuto
札幌医科大学 第二内科
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Maeda Takuto
Second Department Of Internal Medicine Sapporo Medical University
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Sasao Hisataka
Rausu Town National Health Insurance Hospital
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Hotta Daisuke
Department of Cardiology, Sapporo Social Insurance General Hospital
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Saito Norie
Second Department of Internal Medicine, Sapporo Medical University School of Medicine
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Takagi Satoru
Department of Cardiology, Sapporo Social Insurance General Hospital
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Hotta Daisuke
Department Of Cardiology Hokkaido Cardiovascular Hospital
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Shimamoto Kazuaki
Second Department Of Internal Medicine (cardiovascular Medicine) Sapporo Medical University School O
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