Determination of Left Ventricular Mass by Echocardiography in Normotensive Diabetic Patients
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概要
- 論文の詳細を見る
Patients with Type 2 diabetes mellitus(DM) have excessive cardiovascular morbidity and mortality, even in the absence of hypertension. Left ventricular hypertrophy(LVH), which is an ominous prognostic sign and an independent risk factor for cardiac events, is often present in Type 2 DM patients. Forty-two Type 2 DM patients without hypertension, all of whom had been diagnosed more than 10 years ago, were examined in the present study. They had no evidence of renal dysfunction and had not received any anti-hypertensive drugs. Agematched healthy normal subjects (n=47) were recruited as controls. All participants were classified according to the left ventricular mass index(LVMI) using M-mode echocardiography and their systolic function (fractional shortening) was examined. The systolic function was not significantly different between the Type 2 DM and control groups. LVH can be seen even in the normotensive Type 2 DM patients, with these patients still having a higher LVMI than the normal control subjects. Although the plasma insulin levels were not significantly increased in the Type 2 DM patients, the LVMI significantly correlated with plasma insulin levels. However, the LVMI did not significantly correlate with plasma fasting glucose and hemoglobin A1c in the Type 2 DM patients. These results suggest that LVH in Type 2 DM patients without hypertension may be associated with elevated plasma insulin levels.
- 社団法人日本循環器学会の論文
- 2000-11-20
著者
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SUGANO Masahiro
Department of Cardiovascular, Respiratory and Geriatric Medicine, Kyushu University Hospital at Bepp
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MAKINO Naoki
Department of Cardiovascular, Respiratory and Geriatric Medicine, Kyushu University Hospital at Bepp
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Sugano Masahiro
Medical Institute of Bioregulation. Kyushu University
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Makino Naoki
Medical Institute of Bioregulation. Kyushu University
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Makino Naoki
Department Of Cardiovascular Respiratory And Geriatric Medicine Kyushu University Hospital At Beppu
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Makino Naoki
Division Of Molecular And Clinical Gerontology Medical Inst. Of Bioregulation Kyushu Univ.
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YONEMOCHI HIDETOSHI
Department of Medicine, Oita Medical University
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Makino Naoki
Division Of Molecular And Clinical Gerontology Department Of Molecular And Cellular Biology Medical
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Hirayama Hiroyoshi
Departments of Bioclimatology and Medicine Kyushu University
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Sugano Masahiro
Division Of Molecular And Clinical Gerontology Department Of Molecular And Cellular Biology Medical
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Sugano Masahiro
Department Of Cardiovascular Respiratory And Geriatric Medicine Kyushu University Hospital At Beppu
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Hirayama Hiroyoshi
Department Of Bioclimatology And Medicine Medical Institute Of Bioregulation Kyushu University
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Abe Nobuyuki
Abe Medical Clinic
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Makino Naoki
Departent Of Bioclimatology And Medicine Medical Institute Of Bioregulation Kyushu University
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Sugano Masahiro
Division Of Molecular And Clinical Gerontology Medical Inst. Of Bioregulation Kyushu Univ.
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Yonemochi Hidetoshi
Department Of Bioclimatology And Medicine Medical Institute Of Bioregulation Kyushu University
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Sugano Masahiro
Department Of Molecular And Cellular Biology Division Of Molecular And Clinical Gerontology Medical
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Makino Naoki
Department Of Molecular And Cellular Biology Division Of Molecular And Clinical Gerontology Medical
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Sugano Masahiro
Department Of Cardiovascular Respiratory And Geriatric Medicine Kyushu University Hospital At Beppu
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Makino Naoki
Division Of Molecular And Clinical Gerontology Department Of Molecular And Cellular Biology Medical
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Sugano Masahiro
Department Of Bioclimatology And Medicine Medical Institute Of Bioregulation Kyushu University
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