Improvement in Cardiac Function and Free Fatty Acid Metabolism in a Case of Dilated Cardiomyopathy With CD36 Deficiency
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概要
- 論文の詳細を見る
A 27-year-old man diagnosed as having dilated cardiomyopathy (DCM) without myocardial accumulation of ^<123>I-β-methyl-iodophenylpentadecanoic acid, and he was found to have typd I CD36 deficiency. This abnormality of cardiac free fatty acid metabolism was also confirmed by other methods: ^<18>F-fluoro-2-deoxyglucose positron emission tomography, measurements of myocardial respiratory quotient and cardiac fatty acid uptake. Although the type I CD36 deficiency was reconfirmed after 3 months, the abnormal free fatty acid metabolism improved after carvedolol therapy and was accompanied by improved cardiac function. Apart from a cause-and-effect relationship, carvedilol can improve cardiac function and increase free fatty acid metabolism in patients with both DCM and CD36 deficiency.
- 社団法人日本循環器学会の論文
- 2000-08-20
著者
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Komamura Kazuo
Cardiovascular Division, National Cardiovascular Center
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Nakatani Satoshi
The Cardiovascular Division Osaka Police Hospital
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MINATOYA Kenji
National Cardiovascular Center
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Ishida Y
Department Radiology And Nuclear Medicine National Cardiovascular Center
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Ishida Yoshio
Department Of Pathology National Cardiovascular Center
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Kimura Kohji
Departments Of Radiology National Cardiovascular Center
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Hanatani Akihisa
Departments Of Pharmacy National Cardiovascular Center
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Hanatani Akihisa
Organ Transplantation National Cardiovascular Center
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Yamagishi Masakazu
The Cardiol. Division Osaka Keisatsu Hosp
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Hirooka Keiji
Departments Of Cardiology National Osaka Hospital
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Ikeda Yoshihiko
Division Of Pathology National Cardiovascular Center
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Ishida Yoshio
Kanazawa University Hospital
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Yasumura Yoshio
Laboratory Of Molecular Genetics National Cardiovascular Center
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木村 晃二
国立循環器病センター 心臓血管
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HIROOKA Keiji
The Cardiology Division of Medicine, National Cardiovascular Center
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MIYATAKE Kunio
The Cardiology Division of Medicine, National Cardiovascular Center
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Ishida Yoshio
Department Of Applied Physics Faculty Of Engineering Fukui University
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Yasumura Yoshio
The Cardiology Division of Medicine
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Hanatani Akihisa
The Cardiology Division of Medicine
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Kusumoto Miyako
Cardiac Division National Cardiovascular Center
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Hanatani Akihisa
Department Of Organ Transplantation National Cardiovascular Center
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Hanatani Akihisa
National Cardiovascular Center Dep Of Organ Transplantation
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Miyatake Kunio
The Cardiology Division Of Medicine National Cardiovascular Center
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Komamura Kazuo
Cardiovascular Division Osaka Police Hospital
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Nakatani Satoshi
The Cardiology Division Of Medicine National Cardiovascular Center
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