Effects of Metabolically Ischemic, But Viable, Myocardium on QT Dispersion in Patients With Acute Myocardial Infarction : A Study With Resting I-123-BMIPP/Thallium-201 Myocardial Single-Photon Emission Computer Tomography
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概要
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In chronic Q-wave myocardial infarction, QT dispersion is closely correlated with infarct size, but this correlation has not been evaluated for acute myocardial infarction (AMI). The effects of abnormal fatty acid metabolism on QT dispersion were examined in 123 patients with AMI who underwent resting iodine-123-15-iodophenyl 3-methyl pentadecanoic acid (BMIPP)/thallium-201(^<201>Tl) myocardial single photon emission computed tomography (SPECT) and electrocardiographic analysis in the subacute phase. The relationship between BMIPP and ^<201>Tl was defined as match when the total defect score for BMIPP was equal to or smaller than that for ^<201>Tl, and as mismatch when the total defect score for BMIPP was larger than that for ^<201>Tl. Twenty-six patients (21%) demonstrated BMIPP-^<201>Tl match and 97 (79%) demonstrated mismatch. Infarct size was closely correlated with QT dispersion (r=0.67, p<0.001) in patients with BMIPP-^<201>Tl match, but weakly correlated (r=0.30, p<0.005) in patients with BMIPP-^<201>Tl mismatch. For small infarctions, QT dispersion was significantly larger in patients with BMIPP-^<201>Tl mismatch than in those with BMIPP-^<201>Tl match (62±24ms vs 41±18ms, p=0.03), but did not differ between the 2 groups for large infarctions. This study shows that QT dispersion is influenced by infarct size and by the presence of metabolically ischemic but viable myocardium in patients with AMI.
- 社団法人日本循環器学会の論文
- 2000-07-20
著者
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Yamaguchi Junichi
Division Of Cardiology Saitama Prefecture Cardiovascular And Respiratory Center
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Hirata Kumiko
Higashisumiyoshi Morimoto Hospital
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Toda Iku
Division Of Cardiology Bell Land General Hospital
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Hirata Kumiko
Department Of Cardiology Osaka City General Hospital
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Yamagishi Hiroyuki
First Department of Internal Medicine Osaka City University Medical School
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Akioka Kaname
First Department of Internal Medicine Osaka City University Medical School
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Hirata Kumiko
First Department of Internal Medicine Osaka City University Medical School
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Toda Iku
First Department of Internal Medicine Osaka City University Medical School
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Yoshiyama Minoru
First Department of Internal Medicine Osaka City University Medical School
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Teragaki Masakazu
First Department of Internal Medicine Osaka City University Medical School
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Takeuchi Kazuhide
First Department of Internal Medicine Osaka City University Medical School
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Yoshikawa Junichi
First Department of Internal Medicine Osaka City University Medical School
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Ochi Hironobu
Division of Nuclear Medicine, Osaka City University Medical School
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Takeuchi Kazuhide
大阪市立大学 医学研究科循環器病態内科学
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Takeuchi Kazuhide
The First Department Of Internal Medicine Osaka City University Medical School
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Ochi Hironobu
Radiology Osaka City University Medical School
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Ochi Hironobu
Division Of Nuclear Medicine Osaka City University Medical School
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Hirata Kazuto
The Department Of Cardiology Higashisumiyoshi Morimoto Hospital
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Yamashita Hajime
Department Of Internal Medicine And Cardiology Osaka City University Graduate School Of Medicine
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Hirata Kumiko
Higashisumiyoshimorimoto Hospital
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Ochi Hironobu
Dept. Of Radiology Osaka City Univ. Med. School
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Hirota Kazuyoshi
1st Department Of Internal Medicine Osaka City University Medical School
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