Effect of Manidipine Hydrochloride, a Calcium Antagonist, on Isoproterenol-Induced Left Ventricular Hypertrophy
スポンサーリンク
概要
- 論文の詳細を見る
We examined the effect of a calcium antagonist, manidipine hydrochloride, on cardiac hypertrophy and the expression of the atrial natriuretic peptide(ANP), transforming growth factor β_1(TGF-β_1), and extracellular matrix protein genes in rats with isoproterenol-induced cardiac hypertrophy. Rats were continuously infused with saline or isoproterenol(0.5 mg/kg per day)for 7 days using an osmotic minipump. Treatment with manidipine hydrochloride(once a day at 3 mg/kg)began 1 day before minipump implantation and continued until the end of the experiments(each group;n=6). After treatment, left ventricular weight was measured and mRNA was extracted and analyzed by Nortern blot hybridization. Isoproterenol increased left ventricular weight(2.40±0.04g/kg;p<0.01)without increasing blood pressure. ANP, collagen type I and type III, and fibronectin mRNAs were increased 1.5-(p<0.01), 1.9-(p<0.01), 2.7-(p<0.01), and 3.2-fold(p<0.01), respectively, by isoproterenol infusion. However, TGF-β_1, collagen type IV, and laminin B1 and B2 mRNA levels were unchanged by isoproterenol. Manidipine hydrochloride prevented isoproterenol-induced left ventricular hypertrophy(2.26±0.02g/kg;p<0.01)and expression of mRNA of ANP(0.9-fold of the control value;p<0.01), collagen types I(1.1-fold;p<0.01)and type III(1.6-fold;p<0.01), and fibronectin(1.1-fold;p<0.01). Thus, manidipine hydrochloride prevented cardiac hypertrophy and changes in the expression of genes for ANP and interstitial components of extracellular matrix induced by isoproterenol.
- 社団法人日本循環器学会の論文
- 1997-12-20
著者
-
Yamaguchi Junichi
Division Of Cardiology Saitama Prefecture Cardiovascular And Respiratory Center
-
IWAO Hiroshi
Department of Pharmacology, Osaka City University School of Medicine
-
Shimada Kenei
大阪掖済会病院 循環器科
-
Shimada Kenei
Department Of Internal Medicine And Cardiology Osaka City University School Of Medicine
-
Shimada Kenei
ベルランド総合病院 循環器内科
-
Kim-mitsuyama Shokei
熊本大学 医学教育部生体機能薬理学
-
Kim-mitsuyama Shokei
大阪市立大学 医学研究科薬理学
-
Shimada Kenei
Department Of Cardivascular Medicine Osaka Ekisaikai Hospital
-
Toda Iku
Division Of Cardiology Bell Land General Hospital
-
Ozaki Takeshi
Bell land general hospital
-
Akioka Kaname
First Department of Internal Medicine Osaka City University Medical School
-
Toda Iku
First Department of Internal Medicine Osaka City University Medical School
-
Yoshiyama Minoru
First Department of Internal Medicine Osaka City University Medical School
-
Teragaki Masakazu
First Department of Internal Medicine Osaka City University Medical School
-
Takeuchi Kazuhide
First Department of Internal Medicine Osaka City University Medical School
-
Yoshikawa Junichi
First Department of Internal Medicine Osaka City University Medical School
-
Takeuchi Kazuhide
大阪市立大学 医学研究科循環器病態内科学
-
Takeuchi Kazuhide
The First Department Of Internal Medicine Osaka City University Medical School
-
Muro Takashi
Actmce1
-
Muro Takashi
大阪市立大学 医学部循環器病態内科学
-
Muro Takashi
大阪市立大学 医研究 循環器病態内科
-
Hirasawa Akira
京都大学 薬学研究科ゲノム創薬科学
-
Sakata Konomi
Actmce1
-
Hanatai Akihisa
First Department Of Internal Medicine Osaka City Unitersity Medical School
-
HANATANI Akihisa
First Department of Internal Medicine, Osaka City Unitersity Medical School
-
KIM Shokei
Department of Pharmacology, Osaka City Unitersity Medical School
-
OMURA Takashi
First Department of Internal Medicine, Osaka City Unitersity Medical School
-
Katsuma Susumu
Department Of Genomic Drug Discovery Science Kyoto University Graduate School Of Pharmaceutical Scie
-
Iwao Hiroshi
Department Of Pharmacology Graduate School Of Medicine Osaka City University
-
Kim Shokei
Department Of Pharmacolgy Osaka City Unversity Medical School
-
Hanatani Akihisa
Department Of Internal Medicine And Cardiology Osaka City University Graduate School Of Medicine
-
Iwao Hiroshi
Department Of Cardiovascular Medicine Akita University Graduate School Of Medicine
-
Kim Shokei
Department Of Internal Medicine And Cardiology Osaka City University Medical School
-
HANATANI Akihisa
First Department of Internal Medicine Osaka City University Medical School
-
OMURA Takashi
First Department of Internal Medicine Osaka City University Medical School
関連論文
- Documented Subacute Stent Thrombosis Within Thirty Days After Stenting With Sirolimus-Eluting Stent (Cypher^[○!R]) for Acute Myocardial Infarction : A Japanese Single Center Retrospective Non-Randomized Study
- OJ-480 Early Elevation of Serum lnterleukin-6 and High Sensitive CRP Predicts LV Remodeling in Reperfused Myocardial Infarction(Old Myocardial Infarction/Remodeling 1 (IHD) : OJ59)(Oral Presentation (Japanese))
- 1 Pharmacogenomics of β-blocker Therapy in Chronic Heart Failure(New Approaches to Heart Failure-from Pharmacogenomics to Drug Development, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Effects of Gender on Prognosis of Patients With Known or Suspected Coronary Artery Disease Undergoing Contrast-Enhanced Dobutamine Stress Echocardiography
- Quantitative Assessment of Left Ventricular Function During Contrast-Enhanced Dobutamine Stress Echocardiography Predicts Future Cardiac Events in Diabetic Patients
- Pocket-Sized Transthoracic Echocardiography Device for the Measurement of Cardiac Chamber Size and Function
- OJ-198 The Feasibility and Safety of Transnasal Transesophageal Echocardiography(OJ33,Echo/Doppler (New Technology) (I),Oral Presentation (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- Elevated Serum C-Reactive Protein Levels Predict Cardiovascular Events in the Japanese Coronary Artery Disease (JCAD) Study(Epidemiology)
- Impact of Electrocardiographic Left Ventricular Hypertrophy on the Occurrence of Cardiovascular Events in Elderly Hypertensive Patients : The Japanese Trial to Assess Optimal Systolic Blood Pressure in Elderly Hypertensive Patients (JATOS)
- Quantitative Analysis of Myocardial Contrast Enhancement by First-Pass 64-Multidetector Computed Tomography in Patients With Coronary Heart Disease(Imaging)
- Comparison of 64-slice multi-detector computed tomography coronary angiography between asymptomatic, type 2 diabetes mellitus and impaired glucose tolerance patients
- Non-Invasive Assessment of Plaque Rupture by 64-Slice Multidetector Computed Tomography : Comparison With Intravascular Ultrasound
- PJ-885 Electrocardiographic LVH (SV1+RV5) and Cardiovascular Event, Subanalysis of JATOS Study(Hypertension, clinical(10)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- The Simultaneous Assessment of Aortic Valve Area and Coronary Artery Stenosis Using 16-Slice Multidetector-Row Computed Tomography in Patients With Aortic Stenosis Comparison With Echocardiography
- PJ-231 Early and Subtle Neointimal Growth Detection Following Stent Implantation Using Intravascular Ultrasound and Optical Coherence Tomography and Histology(Intravascular endoscopy/Intravascular ultrasound-5 (I) PJ39,Poster Session (Japanese),The 70th A
- FRS-086 Comparison of Accurate Measurement of Aortic Valve Area in Patiens with Aortic Valve Stenosis by Transthoracic Echocardiography versus 16-slice MDCT(New Cardiovascular Imagings-2 (I) FRS18,Featured Research Session (English),The 70th Anniversary A
- Method Analysis for Optimal Continuous Imaging Using Intravascular Optical Coherence Tomography(Coronary Revascularization, PTCA/Stent/DCA/Rotablator/New Device 10 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- PE-222 The Decrease of Plaque Volume during PCI Has Negative Impact on Coronary Flow in Acute Myocardial Infarction(Acute Myocardial Infarction, Clinical (Diagnosis/Treatment) 12 (IHD) : PE38)(Poster Session (English))
- OE-067 Relationship Between Patterns of Calcification and Arterial Remodeling of Culprit Lesions, Comparing Acute Coronary Syndromes with Stable Angina(Acute Coronary Syndrome, Basic/Clinical 3 (IHD) : OE9)(Oral Presentation (English))
- Convalescent Stage Coronary Flow Reserve and Late Myocardial Morphologic Outcomes in Patients With First Anterior Acute Myocardial Infarction
- Slow-Flow Phenomenon during Percutaneous Coronary Intervention in Acute Myocardial Infarction : An Intravascular Ultrasound Study
- The Influences of Hemodialysis and AV-Shunt on Bilateral Internal Thoracic Artery Flows : An Ultrasound Study
- Elevated Plasma Levels of Oxidized Low-Density Lipoprotein Relate to the Presence of Angiographically Detected Complex and Thrombotic Coronary Artery Lesion Morphology in Patients With Unstable Angina
- PE-112 Increased Plasma Oxidized LDL Levels are Associated with the Presence of Angiographically-detected Complex and Thrombotic Lesion Morphology in UAP Patients(Acute coronary syndrome, basic/clinical-5 (IHD) PE19,Poster Session (English),The 70th Anniv
- FRS-114 The Importance of Plaque Hemorrhage and Plaque Inflammation in the Destabilization of Human Carotid Atherosclerotic Plaques(Clinical Aspects of Atherosclerosis (H) FRS23,Featured Research Session (English),The 70th Anniversary Annual Scientific Me
- Plasma Levels of Neopterin Directly Relate to the Severity of Acute Coronary Syndromes (Acute Myocardial Infarction, Clinical (Pathophysiology) 7 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Pro-Oxidant Enzyme Myeloperoxidase Positively Correlates to Oxidized Low Density Lipoprotein in Human Coronary Unstable Plaques(Acute Coronary Syndrome/Changing Strategy (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- PE-113 Intravenous Myocardial Contrast Echocardiography Predicts Regional Wall Motion Worsening and Global Left Ventricular Remodeling after Acute Myocardial Infarction(Echo/Doppler 4 (I) : PE20)(Poster Session (English))
- PE-557 Atrioventricular Delay Optimization under Echocardiographic Guidance in Patients with Normal Left Ventricular Systolic Function(PE093,Echo/Doppler (Others) (I),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese Circulation
- PE-150 Prevalence of Left Atrial Thrombus in Atrial Fibrillation Patients with Anticoagulation Therapy(PE025,Thromboembolism/Antithrombotic Therapy/Thrombolysis 2 (IHD),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulatio
- DPJ-030 Echocardiographic Assessment of Inefficient Left Ventricular Contraction in Patient Selection for Cardiac Resynchronization Therapy(DPJ05,Echo/Doppler (Myocardium) (I),Digital Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Jap
- OJ-196 Dobutamine-Induced Left Ventricular Mechanical Dyssynchrony : A Study Using Real-Time Three-Dimensional Echocardiography(OJ33,Echo/Doppler (New Technology) (I),Oral Presentation (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulat
- FRS-112 Influence of the Early Ticlopidine Discontinuation on Clinical Outcomes following Sirolimmus-Eluting Stent Implantation(FRS23,Clinical Evidence of DES Era (1) (IHD),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japa
- FRS-111 Contemporary Practice Use of Sirolimus-Eluting Stents in Hemodialysis Patients : The Results from HIJ-DES Registry(FRS23,Clinical Evidence of DES Era (1) (IHD),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japanese
- 2 Prolonged Postischemic Regional Left Ventricular Delayed Relaxation or Diastolic Stunning in Patients with Coronary Artery Disease Undergoing Percutaneous Coronary Angioplasty(Frontiers in Diagnostic Echocardiography,Symposium 14 (SY-14) (M),The 73rd An
- 2 Prognostic Factors in Patients with Coronary Artery Disease Treated with Sirolimus-eluting Stent : The HIJ-DES registry(Current Status and Future Perspective of Drug-Eluting Stents,Plenary Session 1 (PL-1) (A),The 73rd Annual Scientific Meeting of The J
- Elevated E/E' Predicts Prognosis in Congestive Heart Failure Patients With Preserved Systolic Function(Heart Failure)
- Assessment of Aortic Atheromatous Plaque and Stiffness by 64-Slice Computed Tomography is Useful for Identifying Patients With Coronary Artery Disease
- Normal Values of Echocardiographic Parameters in Relation to Age in a Healthy Japanese Population : The JAMP Study
- PJ-859 Decreased Ventricular Septal Work Resulting from Dyssynchrony : an Echocardiographic Study Using Left Ventricular Time-area Curves with a Speckle-tracking Method(Echo / Doppler(18)(I),Poster Session(Japanese),The 72nd Annual Scientific Meeting of t
- PJ-823 The evaluation of angiographic restenotic pattern after sirolimus-eluting stents implantation in patients on hemodialysis : From the HIJC DES Registry(Coronary revascularization, PCI(26)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meet
- OJ-253 Normal Values from two-dimensional echocardiography in asymptomatic healthy Japanese adults(Echo / Doppler(04)(I),Oral Presentation (Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-003 Prevention of In-stent Neointimal Proliferation by Pioglitazone Study(POPPS)(Coronary revascularization, PCI(05)(IHD),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Quantitative Assessment of Persistent Regional Myocardial Dysfunction After Myocardial Ischemia Using Exercise Stress Echocardiography with Newly Developed Strain M-mode Imaging(Echo/Doppler 13 (I), The 69th Annual Scientific Meeting of the Japanese Circu
- PJ-496 Relationship Between Inefficient Left Ventricular Contraction and Dyssynchrony : an Echocardiographic Study Using Global and Regional Left Ventricular Time-area Curves(Echo/Doppler(16)(I),Poster Session(Japanese),The 72nd Annual Scientific Meeting
- Atherosclerotic Plaque With Ultrasonic Attenuation Affects Coronary Reflow and Infarct Size in Patients With Acute Coronary Syndrome : An Intravascular Ultrasound Study
- PE-163 Persistent Elevated E/E' Predicts Prognosis In Patients With Diastolic Heart Failure(Echo/Doppler-09, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PE-162 Ischemic Mitral Regurgitation and E/E "are Independent Predictors of Cardiac Events in Patients with Ischemic Heart Disease(Echo/Doppler-09, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-300 Diabetes Predicts Poor Clinical Outcome in Patients with Acute Myocardial Infarction : An Intravascular Ultrasound Study(Acute myocardial infarction, clinical (diagnosis/treatment)-11 (IHD) PJ51,Poster Session (Japanese),The 70th Anniversary Annual
- PE-361 Impact of Statin on Left Ventricular Systolic and Diastolic Indicec in Patients with Ischemic Heart Disease(Echo/Doppler-8 (I) PE61,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-322 Does Arterial Remodeling affect Clinical Outcome Following Stenting in Patients with Acute Coronary Syndrome? : An Intravascular Ultrasound Study(Intravascular Endoscopy/Intravascular Ultrasound 2 (I) : PJ54)(Poster Session (Japanese))
- PJ-201 Acute Hemodynamic Benefits of Biatrial Atrioventricular Sequential Pacing with the Optimal Atrioventricular Delay. : Comparison with Single Atrial Atrioventricular Sequential Pacing.(Arrhythmia, Non-Pharmacological Therapy 7 (A) : PJ34)(Poster Sess
- Acute Hemodynamic Benefits of Biatrial Atrioventricular Sequential Pacing : Comparison with Single Atrial Atrioventricular Sequential Pacing
- A Reverse Flow-Metabolism Mismatch Pattern : A New Marker of Viable Myocardium With Greater Contractility During Dobutamine Stress Than Myocardium With a Flow-Metabolism Mismatch Pattern
- Effects of Metabolically Ischemic, But Viable, Myocardium on QT Dispersion in Patients With Acute Myocardial Infarction : A Study With Resting I-123-BMIPP/Thallium-201 Myocardial Single-Photon Emission Computer Tomography
- PE-082 Inefficient Left Ventricular Contraction Resulting from Dyssynchrony : an Echocardiographic Study Using Left Ventricular Time-area Curves Obtained with a Speckle-tracking Method(Echo/Doppler(05)(I),Poster Session(English),The 72nd Annual Scientific
- Intravascular Ultrasound Imaging : In vitro and vivo validation : ADVANCES IN IMAGING TECHNIQUES FOR DIAGNOSIS OF CARDIOVASCULAR DISEASES
- PJ-297 Efficacy of Multi-detector Computed Tomography in Combination with Coronary Flow Reserve Measurements by Transthoracic Doppler Echocardiography for Detecting Coronary Stenoses(Echo/Doppler(14)(I),Poster Session(Japanese),The 72nd Annual Scientific
- PE-324 E/Ea Estimated by Tissue Doppler Echocardiography is a Powerful Predlctor of Ischemic Stroke(Echo/Doppler(07)(I),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Insufficient Stent Expansion as a Predictive Factor of Neointimal Hyperplasia After Stenting : A study using volumetric intravasculer ultrasound
- Effect of Residual Peri-Stent Plaque Volume on Neointimal Hyperplasia following Stenting : A Volumetric Intravascular Ultrasound Study
- PE-032 Patients with remodeling have severe regional dysfunction a few days after onset of acute myocardial infarction(Nuclear Cardiology 4 (I) : PE6)(Poster Session (English))
- 6 Prognostic Factors in Patients with Coronary Artery Disease in the Revascularization Era : Challenges of the HIJC Study Group(Symposium 18 (SY-18) (H) How can we Make the Best Use of Japanese Evidences for Future Guidelines,Special Program,The 72nd Annu
- Angiotensin II Type 1-Receptor Antagonist Candesartan Cilexitil Prevents Left Ventricular Dysfunction in Myocardial Infarcted Rats
- Doppler Echocardiographic Assessment and Cardiac Gene Expression Analysis of the Left Ventricle in Myocardial Infarcted Rats
- Effect of Manidipine Hydrochloride, a Calcium Antagonist, on Isoproterenol-Induced Left Ventricular Hypertrophy
- PJ-386 A Novel Two-dimensional Echocardiographic Tracking for Automated Assessment of Left Ventricular Wall Motion(Echo/Doppler-11 (I) PJ65,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-163 Automated Assessment of Left Ventricular Volume and Ejection Fraction by Real-time 3-dimensional Echocardiography with a New Automated Analysis Software(Echo/Doppler-12 (I) PJ28,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeti
- 4 Automated Quantitative Assessment of Regional Left Ventricular Function in Patients With Ischemic Heart Disease Using Twodimenisonal Echocardiographic Tracking System(Advances in Cardiovascular Imaging,Symposium 7 (SY7) (I),The 70th Anniversary Annual S
- Three-dimensional Quantitative Analysis of Left Ventricular Segmental Wall Motion in Normal Subjects by New Real-time Echocardiography(Echo/Doppler 4 (I), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Progression of Post-Arteritis Lesions into Atherosclerotic Plaques in Kawasaki Disease(Congenital Heart Disease/Kawasaki's Disease 3 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Assessment of Coronary Flow Velocity Reserve in Angiographically Normal Contralateral Left Anterior Descending Coronary Artery by Transthoracic Doppler Echocardiography(Echo/Doppler 8 (I), The 69th Annual Scientific Meeting of the Japanese Circulation Soc
- Value of Dobutamine Stress Echocardiography Followed by Coronary Flow Reserve Measurement by Transthoracic Doppler Echocardiography for Assessment of Myocardial Ischemia(Echo/Doppler 8 (I), The 69th Annual Scientific Meeting of the Japanese Circulation So
- Clinical Application of Coronary Flow Velocity Reserve Measurement by Transthracic Doppler Echocardiograpy in the Detection of Myocardial Ischemia(Noninvasive Assessment of Myocardial Ischemia : New Approaches Based on the Current Understanding of Cardiov
- PJ-136 Assessment of Myocardial Ischemia Using New Three-Dimensional Dobutamine Stress Echocardiography(Echo/Doppler 6 (I) : PJ23)(Poster Session (Japanese))
- PJ-022 Feasible and Accurate Measurement of Left Ventricular Volume and Ejection Fraction by New Real-Time Three-Dimensional Echocardiography(Echo/Doppler 2 (I) : PJ4)(Poster Session (Japanese))
- OJ-085 Simplified Three-dimensional Measurement of Left Ventricular Volume and Ejection Fraction Using Automated Contour Tracking Method(Echo/Doppler 1 (I) : OJ11)(Oral Presentation (Japanese))
- FRS-007 Value of Coronary Flow Reserve Measurement in Three Major Coronary Arteries as a Screening Tool for Detecting Myocardial Ischemia(Ultrasound Medicine in Cardiology (I) : FRS1)(Featured Research Session (English))
- Coronary Flow Reserve Measurement Still Remains Useful in Diagnosing Coronary Stenosis Even in Patients with Coronary Risk Factors
- The Effect of Oral Glucose Loading on the Coronary Circulation in Healthy Young Adults : Analysis by Transthoracic Doppler Echocardiography
- Automated Quantification of Left Ventricular Function in Patients with Ischemic Heart Disease by Using Biplane Advanced Automated Contour Tracking Method
- Current Characteristics of Infective Endocarditis in Japan : An Analysis of 848 Cases in 2000 and 2001
- 6 New Echocardiographic Approach Using Real-time Three-dimensional Echocardiography in the Clinical Practice(Symposium 15 (SY-15) (I) New Trends in Echocardiography,Special Program,The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-235 Prevalence and Clinical Characteristics of the School Children with Brugada-type ECG(Arrhythmia, Diagnosis/Pathophysiology/EPS 9 (A) : OJ27)(Oral Presentation (Japanese))
- High-Shear-Stress-Induced Activation of Platelet-Derived Microparticles Are Detected by a New Method "ELISA"
- Ruptured Plaque Is Associated with Poor Contractile Recovery after Successful Primary Angioplasty in Patients with Acute Myocardial Infarction
- Usefulness of a 6 Fr Right Judkins Catheter for Mechanically Extracting a Massive Intracoronary Thrombus From an Ectasic Right Coronary Artery : A report on two different cases of thrombectomy
- The Effect of Vasopressin V1- and V2-Receptor Antagonists on Hemodynamics in Early and Late Phase After Myocardial Infarction in Rats
- OJ-270 Noninvasive Coronary Flow Reserve Measurements with Transthoracic Doppler Echocardiography as a Screening Test for Coronary Artery Disease(Echo/Doppler 10 (I) : OJ32)(Oral Presentation (Japanese))
- Mechanisms of Combined Treatment With Celiprolol and Candesartan for Ventricular Remodeling in Experimental Heart Failure
- Endothelin ETA Receptor Antagonist Suppressed ET-1 Content and INOS but Could Not Improve the Cardiac Dysfunction in Dilated Cardiomyopathy
- PJ-394 Beneficial Effects of Erythropoietin on Cardiac Remodeling after Myocardial Infarction(Growth factor/Cytokine-3 (H) PJ67,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- Predictive Value of Sympathetic Myocardail Denervation for Abnormal Coronary Flow Reserve in Patients with Non-Ischemic Dilated Cardiomyopathy
- Influences of Sublingual Nitroglycerin on Coronary Flow Velocity as Detected by Transthoracic Color Doppler Echocardiography
- Detection of Restenosis after Primary Coronary Intervention with Coronary Flow Reserve Using Transthoracic Color Doppler Echocardiography
- Noninvasive Detection of Coronary Artery Using Transthoracic Doppler Echocardiography in Patients with Suspected Acute Myocardial Infarction in Emergency Room
- Impact of Coronary Flow Reserve and Endothelial Function on Incidence of Cardiovascular Events : long-term Follow-up Study(Coronary Circulation, Basic/Clinical 5 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Quantitative Assessment of Myocardial Perfusion by Intravenous Myocardial Contrast Echocardiography With Dobutamine Stress for Detection of Coronary Stenosis in Humans
- Physiologic Assessment of the Left Circumflex Coronary Artery Stenosis by Contrast- Enhanced Transthoracic Doppler Echocardiography : Comparison with Exercise 201-TI SPECT
- Value of diastolic reverse flow detection by contrast enhanced transthoracic Doppler echocardiography : Comparison with coronary angiography and exercise 201-TI scintigraphy