A Trial Procedure to Prevent Aneurysm Formation of the Coronary Arteries by Steroid Pulse Therapy in Kawasaki Disease : THE 6th CONFERENCE ON PREVENTION FOR RHEUMATIC FEVER AND RHEUMATIC HEART DISEASE

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概要

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• Sixty patients with Kawasaki disease in the acute phase were studied using a two-dimensional echocardiography. Coronary lesions in Kawasaki disease were characterized echocardiographically by an increase of echo density of the coronary artery and by dilatation or aneurysm of the coronary artery. These findings appeared in the sequence mentioned above in patients who were studied serially. In the group treated with corticosteroid, 62% of the patients showed a disappearence or an improvement of the coronary dilatation or aneurysm, while only 33% of untreated patients showed such an improvement. In patients with coronary aneurysms on the initial echocardiogram, 53% of the pulse therapy group showed an improvement, but none of the untreated group did. A similar result was obtained by an analysis of its therapeutical effect, according to the number of vessels involved. Thus, corticosteroid pulse therapy was shown to be effective for the prevention of coronary arterial aneurysms in Kawasaki disease, if it was given in a sufficient dose in the acute phase of this disease.

• 社団法人日本循環器学会の論文
• 1982-11-20

著者

• Kamiya Tetsuro

  Department of Pedeatrics

• SUZUKI Atsuko

  Department of Geriatric Medicine, Osaka University Graduate School of Medicine

• Manabe Hisao

  Department of Cardiovascular Surgery National Cardiovascular Center

• Kijima Yoshitami

  Department of Pediatrics National Cardiovascular Center

• Hirose Osamu

  Department of Pediatrics National Cardiovascular Center

• Kamiya Tetsuro

  Department Of Perdiatrics National Cardiovascular Center

• Manabe Hisao

  Department Of Cardiac Surgery National Cardiovascular Center

• Hirose Osamu

  Department Of Gastroenterology And Medicine Faculty Of Medicine Fukuoka University

• Hirose Osamu

  Department Of Perdiatrics National Cardiovascular Center

• Kijima Yoshitami

  Department Of Perdiatrics National Cardiovascular Center

• Suzuki Atsuko

  Department Of Perdiatrics National Cardiovascular Center

• Suzuki Atsuko

  Department Of Geriatric Medicine Osaka University Graduate School Of Medicine

• Suzuki Atsuko

  Department Of Cardiology Seirei Mikatahara Hospital

• KAMIYA Tetsuro

  Department of Cardiovascular Pediatrics, National Cardiovascular Center

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