Long-Term Inhalation of Nitric Oxide for a Patient With primary Pulmonary Hypertension
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概要
- 論文の詳細を見る
Primary pulmonary hypertension is a disease with a high mortality rate and for which there is no saticfactory medical treatment. The safety of long-term inhalation of nitric oxide(NO)as a treatment is described. A 9-year-old girl inhaled NO for 32 weeks, accompanied with oral administration of beraprost sodium. Although NO did not improve her long-term prognosis, it eased the patient's dyspnea and increased her blood oxygenation. At doses of 20 ppm or more, attempts to withdraw from inhaled NO seemed to lead to an immediate elevation of the pulmonary artery pressure. This rebound phenomenon did not happen at doses under 5 ppm. This case study suggests that long-term inhalation of NO is safe and effective, but that pulmonary hypertension may rebound following withdrawal at higher doses of NO.
- 社団法人日本循環器学会の論文
- 1998-11-20
著者
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NAKAMURA Tsuneyuki
Department of Pediatrics, Kanazawa Medical University
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TAKAHASHI Hiroaki
Department of Pediatrics, Kanazawa Medical University
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Nakamura Tsuneyuki
Department Of Chemistry Faculty Of Science And Technology Keio University
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Koh Eikan
Department Of Pediatrics Kanazawa Medical University
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Niimura Junko
Department Of Pediatrics Kanazawa Medical University
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Yamakage Hitoyoshi
Department of Pediatrics, Kanazawa Medical University
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Yamakage Hitoyoshi
Department Of Pediatrics Kanazawa Medical University
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Takahashi Hiroaki
Department Of Pediatrics Kanazawa Medical University
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Takahashi Hiroaki
Department Of Biochemistry And Molecular Biology Graduate School Of Science And Engineering Saitama
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