Metaiodobenzylguanidine and Heart Rate Variability in Heart Failure

概要

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It is assumed that the low-frequency power(LF)of heart rate variability(HRV)increases with progress of congestive heart failure(CHF), therefore positively correlating with cardiac ^123I-metaiodobenzylguanidine(MIBG)washout. It is demonstrated here that HRV, including normalized LF, correlated inversely with MIBG washout and positively with the ratio of heart-to-mediastinum MIBG activity in controls and CHF patients, whereas these correlations were not observed within CHF patients. Thus MIBG washout may increase and HRV including normalized LF may decrease with CHF, although the HRV and MIBG measures may not similarly change in proportion to the severity of the cardiac autonomic dysfunction in CHF.
社団法人日本循環器学会の論文
1998-09-20