SIMULTANEOUS DUAL MYOCARDIAL IMAGING WITH IODINE-123-β-METHYL IODOPHENYL-PENTADECANOIC ACID (BMIPP) AND THALLIUM-201 IN PATIENTS WITH CORONARY HEART DISEASE
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概要
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To assess the clinical value of simultaneous dual myocardial imaging with iodine-123-β-methyl-iodophenyl-pentadecanoic acid (^<123>I-BMIPP) and thallium-201 (^<201>Tl), myocardial imaging was performed at rest and during exercise in seven patients with coronary heart disease. When ^<123>I-BMIPP and ^<201>Tl images were compared, the initial exercise and resting images agreed 87% and 64%, respectively. In the initial resting images, the regional uptake of ^<123>I-BMIPP was frequently less than that of ^<201>Tl. The incidence of exercise-induced reversible defects by ^<201>Tl in the Tl>BMIPP regions was significantly higher than that in the Tl=BMIPP regions (57% vs 4%, p<0.01) and the incidence of coronary narrowing of more than 90% in the Tl>BMIPP regions was also significantly higher than that in the Tl=BMIPP regions (91% vs 38%, p<0.01). In addition, this disparity (Tl>BMIPP) was found more frequently in regions with abnormal wall motion than in regions with normal wall motion (hypokinetic regions; 68%, severe hypokinetic or akinetic regions; 50%, vs normokinetic regions; 4%, p<0.01). In contrast, the uptake of ^<123>I-BMIPP correlated closely with that of ^<201>Tl in normal myocardium and the uptake of both ^<123>I-BMIPP and ^<201>Tl was severely reduced in myocardium with severe ischemia during exercise and prior infarction. These results indicate that dual myocardial imaging with ^<123>I-BMIPP and ^<201>Tl may provide a unique means of identifying patients with metabolically disturbed myocardium, such as hibernating and stunned myocardium.
- 社団法人日本循環器学会の論文
- 1994-01-20
著者
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Ohnishi K
Third Department Of Internal Medicine Hamamatsu University School Of Medicine
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Ohnishi Kazunori
東北大学病院 血液･免疫科
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Yamazaki Noboru
The Third Department of Internal Medicine
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Okayama Kenichi
Department Of Internal Medicine Iii Hamamatsu University School Of Medicine
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Odagiri Keiichi
浜松医科大学 救急医学
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Odagiri Keiichi
Department Of Medicine Hamamatsu Red Cross Hospital
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KOBAYASHI AKIRA
The Third Department of Internal Medicine, Hamamatsu University School of Medicine
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KURATA Chinori
YAMAHA Health Care Center
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Ohmine Ken
Department Of Hematology Jichi Medical School
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Tawarahara Kei
Department Of Cardiology Hamamatsu Red Cross Hospital
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Tawarahara Kei
Department Of Cardilogy Hamamatsu Red-cross Hospital
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Tawarahara Kei
The Third Department Of Internal Medicine Hamamatsu University School Of Medicine
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Ohshima Koichi
First Department Of Pathology Fukuoka University
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Yamazaki Noboru
Third Division Department Of Internal Medicine Hamamatsu University School Of Medicine
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Yamazaki Noboru
The Third Department Of Internal Medicine Hamamatsu University School Of Medicine
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Oshimi Kazuo
Department Of Internal Medicine Hamamatsu University School Of Medicine
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Kobayashi Akira
The Department Of Medicine Iii Hamamatsu University School Of Medicine
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Taguchi Takahisa
The Third Department Of Internal Medicine Hamamatsu University School Of Medicine
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Okayama Kenichi
The Third Department Of Internal Medicine Hamamatsu University School Of Medicine
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Kobayashi Akira
Internal Medicine Iii Hamamatsu University School Of Medicine
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Yamazaki Noboru
Third Department Of Internal Medicine Hamamatsu University School Of Medicine
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Ohnishi Kazunori
The "lung Injury By Bortezomib" Joint Committee Of The Japanese Society Of Hematology And
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KURATA CHINORI
The Third Department of Internal Medicine, Hamamatsu University School of Medicine
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AOSHIMA SHIGEYUKI
The Third Department of Internal Medicine, Hamamatsu University School of Medicine
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KANEKO MASAO
Department of Radiology, Hamamatsu University School of Medicine
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Kaneko Masao
Department Of Radiology Hamamatsu University School Of Medicine
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Kurata Chinori
Department Of Medicine Iii Hamamatsu University School Of Medicine
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Ohhashi Kyoichi
Department Of Clinical Pharmacology And Therapeutics Hamamatsu University School Of Medicine
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Kobayashi Akira
The Third Department Of Internal Medicine Hamamatsu University School Of Medicine
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Aoshima Shigeyuki
The Third Department Of Internal Medicine Hamamatsu University School Of Medicine
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Kurata Chinori
The Third Department Of Internal Medicine Hamamatsu University School Of Medicine
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Kaneko Masao
Department Of Chemistry Ibaraki University
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Yamazaki Noboru
The 2nd Dept. Of Intern Med. Nagoya Univ. School. Of Med.
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Yamazaki Noboru
Nanotechnology Research Institute National Institute Of Advanced Industrial Science And Technology (
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