A Hypothesis on Radiation-Induced Immunity Polarization and Its Relation to Disease Development in Atomic-Bomb Survivors

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概要

• 論文の詳細を見る
• 日本放射線影響学会の論文

著者

• Sofuni Toshio

  Div. Genetics And Mutagenesis Natl. Inst. Of Health Sciences

• SEYAMA Toshio

  Department of Radiobiology, Radiation Effects Research Foundation

• KUSHUNOKI Yoichiro

  Radiat. Effects Res. Found.

• Hayashi Tomonori

  Department Of Radiobiology/molecular Epidemiology Radiation Effects Research Foundation

• Hayashi Tomonori

  Department Of Radiobiology Radiation Effects Research Foundation

• Yamaoka Mika

  放射線影響研究所

• Kusunoki Y

  Department Of Radiobiology/molecular Epidemiology Radiation Effects Research Foundation

• Kubo Yoshiko

  Depts. Of Radiobiology

• Seyama Toshio

  Depts. Radiobiol. Radiation Effects Res. Foundation

• Sofuni Toshio

  Department Of Radiobiology Radiation Effects Research Foundation

• Seyama Toshio

  Radiation Effects Research Foundation

• Seyama Toshio

  Department Of Radiobiology Radiation Effects Research Fouondation

• Fujiwara S

  Department Of Clinical Studies Radiation Effects Research Foundation

• Ohnishi Hisashi

  Depts. Radiobiology

• Kushunoki Yoichiro

  Radiobiology Radiation Effects Res. Found.

• KUSUNOKI Yoichiro

  Depts. Radiobiology

• HAYASHI Tomonori

  Depts. Radiobiology

• MORISHITA Yukari

  Depts. Radiobiology

• YAMAOKA Mika

  Depts. Radiobiology

• FUJIWARA Saeko

  Depts. Clinical Studies, Radiation Effects Res. Found.

• KODAMA Kazunori

  Depts. Clinical Studies, Radiation Effects Res. Found.

• KYOIZUMI Seishi

  Depts. Radiobiology

• Kusunoki Yoichiro

  Radiobiology Radiation Effects Res. Found.

• Seyama Toshio

  Dept. Of Radiobiology Rerf.

• Kusunoki Yoichiro

  Department Of Radiobiology Radiation Effects Research Foundation

• Kusunoki Yoichiro

  Depts. Of Radiobiology

• Kusunoki Yoichiro

  Dept. Radiobiology Radiation Effects Res. Found.

• YAMAOKA Mika

  Depts. of Radiobiology

• MORISHITA Yukari

  Dept. of Radiobiology, Radiation Effects Res. Found., Hiroshima

関連論文

• No induction of interchromosomal recombination by X-ray on thymidine kinase gene in human lymphoblast TK6 and its derivative cells
• Radiation sensitivity and genomic instability in the hematopoietic system : Frequencies of micronucleated reticulocytes in whole-body X-irradiated BALB/c and C57BL/6 mice
• Perspectives on cancer immuno-epidemiology
• X-Irradiation Induces Up-regulation of ATM Gene Expression in Wild-type Lymphoblastoid Cell Lines, but Not in Their Heterozygous or Homozygous Ataxia-telangiectasia Counterparts
• Mitochondrial DNA Deletion in Human CelLB Exposed to Radiation.
• T-cell differentiation from one HPRT mutant stem cell in a male A-bomb survivor.
• A Radiation-induced Murine Ovarian Granulosa Cell Tumor Line : Introduction of v-ras Gene Potentiates a High Metastatic Ability
• Molecular analysis of 4 primary tumors in one individual who received Thorotrast
• Somatic Mutant Fraction and Cancer Risk in Atomic Bomb Survivors
• Association between inflammatory and infectious markers among Atomic Bomb Survivors; Implication for mechanism of increase in cardiovascular disease.
• Atherosclerosis-Related Microbial Infection in Atomic Bomb Survivors
• Somatic Cell Mutations in Atomic Bomb Survivors : II. BIOLOGICAL EFFECTS
• In vitro X-irradiation is able to cause RET oncogene rearrangement.
• Analysis of BCR-ABL fusion genes in vivo.
• 5 Late Effects of Atomic Bomb Radiation on Plasma Inflammatory Cytokines(Atomic bomb effects, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• O-17. Is there evidence for genetic instabilities in lymphocytes of A-bomb survivors? : chromosome analysis of clonally expanded T-cell populations by M-FISH method(Abstracts of the oral and poster presentations,Abstracts of the 55th Annual Meeting of the
• O-16. Radiation-induced translocations in T cells of Hiroshima A-bomb survivors(Abstracts of the oral and poster presentations,Abstracts of the 55th Annual Meeting of the Society of Chromosome Research)
• 55 Chromosome Aberrations, Clone Formation, and Leukemia(Chromosome aberrations, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 4 Fetal Mice are Resistant to Radiation-Induced Translocations(Atomic bomb effects, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Chromosome Aberration Frequency in the Survivors Exposed in Utero : Are Lymphocytes in the Fetus Radioresistant for the Induction of Chromosome Aberrations?
• Origin of Clonal Chromosome Aberrations in Lymphocytes of A-bomb Survivors. Part 2 : CD4 and CD8 T-cells
• Random Location of Human Chromosomes in Interphase Nuclei
• S-values are not a signature for a significant contribution of neutrons to the radiation dose received by atomic-bomb survivors.
• Detection of clonal chromosome aberrations by FISH in the A-bomb survivors.
• Evaluation of possible population bias among high-dose atomic-bomb survivors in the frequency of the HLA Class II gene types.
• Translocation breakpoints distribute less frequently in chromosome terminal portion in lymphocytes of A-bomb survivors
• Establishment of an in vivo somatic mutation assay at the T-cell receptor gene in the mouse.
• Current Summary of Lymphocyte Survival Study : II. BIOLOGICAL EFFECTS
• Life-span of human memory T cells estimated by T-cell receptor mutations induced by radiation exposure.
• Statistical Approach to Predict Presence of Clonal Chromosome Aberrations
• Why Cancer Risks in A-Bomb Survivors Levels Off above 2 Sv?
• Chromosome Aberrations and Genetic Instability in Lymphocytes from A-Bomb Survivors
• Frequencies of Stable Chromosome Aberrations in Atomic Bomb Survivors-New Insights of Dose ResponseCurves by Shielding Categories
• T-lymphocyte Stem Cell Structure Deduced from Clonal Chromosome Aberrations
• FISH examination of blood lymphocytes from Mayak nuclear workersNori NAKAMURA1, L. E. BURAK2, Yoshiaki KODAMA1, Mimako NAKANO1, Kazuo OHTAKI1, Masahiro
• Estimation of minimum length of translocated chromosome tips detectable by FISH.
• Comparison of iranslocation frequencies between FISH and conventional methods in lymphocytes from A-bomb survivors.
• Detection of Ataxia telangiectasia mutated (ATM) gene product. Yuko
• Effect of ionizing radiation on mitochondrial memebrance potential in human peripheral lymphocyte subpopulations.
• Molecular analysis of mutant Fc γ receptor III (Fc γ R III) gene in neutrophils.
• Development of a Nobel Assay System to Detect Human Somatic Mutations Using Neutrophils. I. At the Fcy Receptor III Locus
• Flow-cytometric measurements for subsets of T, B, and NK cells among atomic-bonib survivors.
• Risks of diabetes and HLA types among atomic-bomb survivors
• Antimutagenic structural modification of quinoline assessed by an in vivo mutagenicity assay.
• Anti-inflammatory effects of Na^+/H^+ exchanger inhibitors
• Carcinogenic Effects of Tritiated Water (HTO) in Mice: In Comparison to those of Neutrons and Gamma-rays
• Activation of the RET oncogene in childhood thyroid cancers from the Chernobyl area.
• Activated RET Oncogene in Thyroid Cancer of Children Residing in Area Contaminated by the Chernobyl Accident
• Detection of Hepatis B Virus in Liver Cancer among Atomic-bomb Survivors
• Overview of Immunological Studies on A-bomb Survivors : II. BIOLOGICAL EFFECTS
• T-Cell Responses to Staphylococcus Aureus Toxins in A-bomb Survivors
• Role of Caspases and Reactive Oxygen in Radiation-Induced Apoptosis : Comparison with Fas-Mediated Apoptosis
• A Hypothesis on Radiation-Induced Immunity Polarization and Its Relation to Disease Development in Atomic-Bomb Survivors
• Effect of Atomic-Bomb Radiation on Cytokine and Immunoglobulin levels
• Histological and Molecular Changes by X-irradiation in Human Thyroid Tissues Transplanted into SCID mice
• Hyperparathyroidism : II. BIOLOGICAL EFFECTS
• Molecular Analysis of p53 Gene Mutations in Skin Cancers of the A-bomb Survivors.
• A Dose Dependent Increase in the Frequency of p53 Mutations in Hepatocellular Carcinomas of the Atomic Bomb Survivors.
• Radiation induced oncogene rearrangements
• Spontaneous and X-radiation induced genetic instability at the TCR gene is dependent on the type of p53 mutation
• A Novel SCID Mouse Model for Studying Spontaneous Metastasis of Human Lung Cancer to Human Tissue
• Search for the BCR-ABL Gene in the Peripheral Blood of A-bomb Survivors and Radioiherapeutic Patients
• The SCID-hu Mouse Model for Human Radiation Biology : Establishing an Epilation Model
• CARCINOGENIC EFFECT OF TRITIATED WATER (HTO) IN MICE IN COMPARISON WITH THOSE OF FISSION NEUTRONS AND GAMMA-RAYS
• Flow Cytometric Detection of Mouse T Cells Lacking Expression of the Major Histocompatibility Complex Antigen Class I Allele
• Mutagenicity Tests Using Cultured Human Cells : Application of Gene Mutation Assay in Thymidine Kinase (tk) Gene of A Human Lymphoid Cell Line (Tk6)
• Reconstruction of the human hematolymphoid system in NOD/SCID-hu mice.
• Participation of the mitochondrial genome in X-ray induced reproductive death and apoptosis.
• Involvement of reactive oxygen and Bcl-2 in radiation-induced apoptosis.
• Illegitimate Recombination Leading to Genetic Instability in p53-mutant Human Lymphoblastoid cells
• Analysis of gene mutations in p53 defective WTK-1 cells
• Radiation-Induced Apoptosis and Cell Cycle Changes in Human Small Intestinal Epithelia
• Chromosome Analysis of Lymphocytes from Cancer Patients given X-ray Therapy by FISH and Calculation of Equivalent Exposure Doses
• 短期試験法による長期毒性の予測 (長期毒性評価とその問題点)

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