2.Bradykininの血管作用(第2報) : 血液灌流標本における作用(第2回プラズマキニン研究会)

概要

論文の詳細を見る
The action of bradykinin was studied using isolated rabbit ears perfused with its blood. Administration of 0.05 ml of bradykinin in the concentration of 10^-7 g/ml caused an increase of venous outflow, and this vasodilatig action of bradykinin was more effective than that of acetylcholine in the same concentration. However, when the ear was perfused with blood saturated with carbon dioxide or with Ringer's solution containing blood cells saturated with pure oxygen, bradykinin induced vasoconstriction conversely. Using plasma or serum as the perfusate, the vasodilating action of bradykinin was observed. In the preparation of the central artery of the ear perfused with blood, the outflow was slightly increased by bradykinin, while in the marginal vein preparation, it was decreased as markedly as in perfusing with Ringer's solution.
日本アレルギー学会の論文
1968-04-30