1.Bradykininの血管作用(第1報) : Ringer液使用標本における作用(第2回プラズマキニン研究会)

概要

論文の詳細を見る
The actions of bradykinin on the blood vessels were investigated in various methods using Ringer's solution as perfusate and medium. Bradykinin produced a decrease in outflow from the isolated rabbit whole ear, and guinea-pig's and rat's hind legs. When adrenaline was contained in Ringer's solution or the innervated rabbit ear was used, bradykinin also produced a decrease in outflow, while acethlcholine produced an increase. In order to find out the site where the vasoconstriction was caused, the new method was deviced by the authors in which the rabbit ear artery or vein was perfused separately. It was found in this method that bradykinin caused no change in the arterial preparation but a decrease in outflow in the venous preparation. Bradykinin induced marked contraction of the strips from jugular and posterior caval vein, but no change in the strips from carotic artery and aorta. These findings lead to the conclusion that bradykinin caused a decrease in outflow from the vessels which was due to the constriction of veins.
日本アレルギー学会の論文
1968-04-30