気管支喘息患者に於ける真菌類加熱抽出エキス及び細菌類加熱ワクチンによる皮膚反応ほか

概要

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The sensitivity to four airborne molds (Aspergillus, Penicillium, Cladosporium and Alternaria), which were found most frequently in the Tokyo area, was investigated through skin tests. The mold allergens used were heat-extracted solutions. Fifty-nine per cent of the asthmatics and 18.7 per cent of the non-asthmatics showed positive immediate skin reactions to one or more mold extracts and there was a significant difference in both groups. Therefore, it seemed that these molds would play an important role as asthmogenic allergens. In the skin tests with six heat-killed bacterial vaccines (Streptococcus hemolyticus et viridans, Staphylococcus aureus et albus, Diplococcus pneumoniae and Neisseria), the incidence of the positive reactions to one or more bacterial vaccines in the asthmatics and nonasthmatics was 60 per cent and 25 per cent, respectively and showed an obvious difference. This suggested that bacteria would act as allergens. Positive skin reactions to tomato and lobster extracts showed high incidences in the patients with urticaria.
日本アレルギー学会の論文
1962-10-30