気管支喘息アレルゲンとしての空中真菌類に関する研究

概要

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The authors studied the seasonal variations of the spore counts of air-borne fungi in the Tokyo area by the culture plate method and the incidence of mold sensitivity in asthmatics by skin tests. The most frequently found air-borne fungi were Oospora, Cladosporium, Penicillium, Alternaria and Aspergillus, but as regards the Oospora species identification was uncertain. Cladosporium and Penicillium were abundant in the period from late autumn to winter. Contrary to the above-mentioned molds, Alternaria was abundant in the period from Spring to Summer. Aspergillus increased slightly in Spring and late Autumn. In the asthmatics, the incidences of of positive skin reactions to four mold extracts prepared by the Hollister-Stier Laboratories were: 7.4 percent against Aspergillus and Cladosporium, 12.3 percent against Trichoderma, and 14.8 percent against penicillium. However, 29.6 percent of the asthmatics showed a positive reaction to the skin tests with one or more of the tested mold extracts, and all of these reactions appeared in patients with house dust sensitivity, which correspondend to 37.5 percent of the latter. The positive skin reactions to eight mold and three bacterial extracts prepared by us were also not so frequent and in 0 to 15.3 percent of the asthmatics.
日本アレルギー学会の論文
1961-03-30