Histological Changes in the Rat Common Carotid Artery Induced by Aneurysmal Wrapping and Coating Materials
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概要
- 論文の詳細を見る
ラット総頚動脈にフィブリン糊、ビオボンド、ペンシーツなどの動脈瘤補強材の内、いずれか一つを局所投与し、3カ月までの病理変化を検討した。フィブリン糊は、2週目に高度炎症反応に囲まれ外膜に軽度炎症反応をもたらしたが、2カ月以内に吸収、消失した。ビオボンドは、血管壁の慢性炎症反応、中膜壊死、中膜と外膜の繊維化による血管壁肥厚をもたらした。ベンシーツは、外膜の結合織増加をもたらしたが、明らかな中膜変化をもたらさなかった。ベンシーツ自体は不変のままで、血管壁と強く癒着した。内膜変化は全例で認められなかった。閉塞性血管病変は観察されなかったが、ビオボンドが動脈瘤術後の血管狭窄の原因になり得ると考えられた。
- 1999-02-15
著者
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YASUI Nobuyuki
Department of Surgical Neurology, Research Institute for Brain and Blood Vessels-Akita
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Yasui Nobuyuki
Department Of Neurological Surgery Research Institute For Brain And Blood Vessels-akita
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Yasui Nobuyuki
Departments Of Surgical Neurology Research Institute For Brain And Blood Vessels-akita
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YOSHIDA Yasuji
Department of Pathology Research institute for Brain and Blood Vesels
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KAWAMURA Shingo
Departments of Sugical Nerology Research institute for Brain and Blood Vesels
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Yoshida Yasuji
Department Of Food And Nutrition Faculty Of Agriculture Kinki University
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Yoshida Yasuji
Departments Of Surgical Pathology Research Institute For Brain And Blood Vessels-akita
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Herrera Oscar
秋田県立脳血管研究センター脳神経外科
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Kawamura Shingo
Department Of Surgical Neurology Research Institute For Brain And Blood Vessels-akita
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Kawamura Shingo
Departments Of Surgical Neurology Research Institute For Brain And Blood Vessels-akita
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