Task-Related Signal Decrease on Functional Magnetic Resonance Imaging
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概要
- 論文の詳細を見る
An atypical pattern of signal change was identified on functional magnetic resonane (fMR) imaging in pathologic patients. Three normal volunteers and 34 patients with pathologic lesions near the primary motor cortex underwent fMR imaging with echo-planar imaging while performing a hand motor task. Signal intensities were evaluated with the z-score method, and the time course and changes of the signal intensity were calculated. Nine of the 34 patients with pathologic lesions displayed a significant task-related signal reduction in motor-related areas. They also presented a conventional task-related signal increase in other motor-related areas. The time courses of the increase and decrease were the inverse of each other. There was no significant difference between rates of signal increase and decrease. Our findings suggest that this atypical signal decrease is clinically significant, and that impaired vascular reactivity and altered oxygen metabolism could contribute to the task-related signal reduction. Brain areas showing such task-related signal decrease should be preserved at surgery.
- 日本脳神経外科学会の論文
- 2001-10-15
著者
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TAMAKI Norihiko
Department of Neurosurgery, Kobe University School of Medicine
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HARA Yoshie
Department of Neurosurgery, Hyogo Emergency Medical Center and Kobe Red Cross Hospital
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Tamaki Norihiko
Department Of Meurosurgery Kobe University School Of Mridicine
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NAKAMURA Mitsugu
Department of Neurosurgery, Kobe University School of Medicine
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TAMURA Shogo
Department of Neurosurgery, Kobe University School of Medicine
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KITAMURA Junji
Kitamura Clinic
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Hara Yoshie
Department Of Neurosurgery Hyogo Emergency Medical Center And Kobe Red Cross Hospital
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Hara Yoshie
Department Of Neurosurgery Kobe University School Of Medicine
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Tamura Shogo
Department Of Neurosurgery Kobe University School Of Medicine
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Nakamura Mitsugu
Department Of Internal Medicine Chiba Municipal Hospital
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Nakamura Mitsugu
Department Of Neurosurgery Kobe University School Of Medicine
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