Effects of Bromocriptine and Terguride on Cell Proliferation and Apoptosis in the Estrogen-stimulated Anterior Pituitary Gland of the Rat
スポンサーリンク
概要
- 論文の詳細を見る
The effects of bromocriptine and terguride on the estrogen-stimulated anterior pituitary gland of the female Wistar rat were investigated. Pituitary weight and serum prolactin (PRL) levels were reduced by treatment with bromocriptine or terguride. Immunohistological staining for proliferating cell nuclear antigen (PCNA) revealed that the PCNA labeling index of PRL-producing cells was significantly decreased by treatment with bromocriptine or terguride compared with untreated cells. The number of apoptotic cells analyzed by the terminal deoxynucleotidyl transferase-mediated deoxyuridinetriphos-phate-biotin nick end labeling method was significantly increased in rats treated with bromocriptine or terguride. Suppression of cell proliferation and induction of apoptosis are important effects of bromocriptine and terguride in the treatment of prolactinomas and other hyperprolactinemias.
- 日本脳神経外科学会の論文
- 1997-12-15
著者
-
KOKUNAI Takashi
Department of Neurosurgery, Kobe University School of Medicine
-
TAMAKI Norihiko
Department of Neurosurgery, Kobe University School of Medicine
-
Tamaki Norihiko
Department Of Neurosurgery Kobe University School Of Medicine
-
Tamaki Norihiko
Department Of Meurosurgery Kobe University School Of Mridicine
-
Kokunai Takashi
Department Of Neurosurgery Kobe University School Of Medicine
-
YONEZAWA Kazuki
Department of Neurosurgery, Kobe University School of Medicine
-
Yonezawa Kazuki
Department Of Neurosurgery Kobe University School Of Medicine
-
米澤 一喜
Department of Neurosurgery, Kobe University School of Medicine
関連論文
- Pineoblastoma Showing Unusual Ventricular Extension in a Young Adult : Case Report
- Polypropylene Mesh Substitute for the Fascial Defect After Using for the Dural Repair : Technical Note
- In Vivo Gene Transfer into the Periventricular Region by Electroporation
- Cerebellopontine Angle Ependymoma with Internal Auditory Canal Enlargement and Pineal Extension : Case Report
- Delayed Cerebrospinal Fluid Rhinorrhea Seven Months After Transsphenoidal Surgery for Pituitary Adenoma : Case Report
- Use of Microvascular Doppler Sonography in Aneurysm Surgery on the Anterior Choroidal Artery
- S-II-17. Neuroradiologic Study of the Normal Pressure Hydrocephalus
- S-II-3. Intrathecal Saline Infusion Test in Hydrocephalus
- Metastatic Bronchogenic Carcinoma with Human Chorionic Gonadotropin Production Manifesting as Cerebellar Hemorrhage : Case Report
- Giant Intracranial Aneurysms : Magnetic Resonance Imaging Follow-up and Clinical Symptoms
- Congenital Hydrocephalus Mimicking Dandy-Walker Syndrome Induced by 6-Aminonicotinamide Injection in Pregnant Rat
- Surgical Approaches to Foramen Magnum Meningioma : Report of Three Cases
- A-71. Experimental Brain Tumors Produced by Transplacental Administration of Ethylnitrosourea : Microangiographic study of the tumor vessels,and comparative studies on chemotherapies and radiation therapy of the experimental brain tumors
- Cerebral Oximetry for the Detection of Cerebral Ischemia During Temporary Carotid Artery Occlusion
- Subependymoma in the Lateral Ventricle Incidentally Detected by Routine Brain Examination : Case Report
- Ferroelectric Properties in Piezoelectric Semiconductor Zn_M_xO (M=Li, Mg)
- Dielectric Study in K_2TeO_3 : A New Ferroelectric
- Task-Related Signal Decrease on Functional Magnetic Resonance Imaging
- Choroid Plexus Metastasis of Lung Carcinoma : Case Report
- Craniocervical Junction Synovial Cyst Associated with Atlanto-Axial Dislocation
- Retroperitoneal Approach for Lumbar Lateral Meningocele : Case Report
- Growth Hormone-producing Pituitary Adenomas: MR Characteristics and Pre- and Postoperative Evaluation
- Relationship between Expression of p21^WAF1/CIP1 and Radioresistance in Human Gliomas
- Acute Subdural Hematoma of Arterial Origin following Ventriculoperitoneal Shunting : Report of Two Cases
- Effect of Cerebrospinal Fluid Shunting on Experimental Syringomyelia : Magnetic Resonance Imaging and Histological Findings
- Delayed Onset of Intraventricular Hemorrhage Following Removal of Acute Subdural Hematoma : Case Report
- Surgical Experience With Skull Base Approaches for Foramen Magnum Meningioma
- Fenestration of the Internal Carotid Artery Associated with an Ischemic Attack : Case Report
- Neonatal Orbital Teratoma with Intracranial Extension : -Case Report-
- Chronic Subdural Hematoma in Elderly People: Present Status on Awaji Isl and Epidemiological Prospect
- Expression of Nerve Growth Factor Receptor by Human Primitive Neuroectodermal Tumors
- Multicentric Glioblastoma Multiforme Occurring in the Supra- and the Infratentorial Regions : Case Report
- Effects of Bromocriptine and Terguride on Cell Proliferation and Apoptosis in the Estrogen-stimulated Anterior Pituitary Gland of the Rat
- Radiation-induced Brain Damage in Children : Histological Analysis of Sequential Tissue Changes in 34 Autopsy Cases
- Intraosseous Meningioma with a Dural Defect : Case Report
- Intraarterial infusion of papaverine and change of cerebral hemodynamics in symptomatic cerebral vasospasm
- Diagnostic imaging of spinal cord lesions