悪性神経膠腫から線維肉腫へのtransformationがみられた脳腫瘍の1剖検例

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The authors describe a case of a primary brain tumor composed of both gliomatous and sarcomatous elements. Surgical specimen, six months preceding his death, shows anaplastic astrocytoma with moderate endothelial proliferation of the blood vessel. Huge, relatively circumscribed subcortical tumor extending to the epidural space is observed on cross section of the autopsy specimen Epidural mass us composed of sarcomatous tumor and subcortical one reveals islands of sarcomatous tissue surrounding by gliomatous stroma. In deeper region of the brain, proliferation of astrocytes and vascular hyperplasia are noticed This tumor may be considered analogous to the gliosarcoma, which us described by Feigin The histogenesis of the mixed tumor us discussed with special reference to the gliosarcoma.
日本脳神経外科学会の論文