Long-term Outcome for SUrgically Treated Cervical Spondylotic Radiculopathy and Myelopathy
スポンサーリンク
概要
- 論文の詳細を見る
Long-term follow-up results were examined to verify the efficacy of anterior osteophytectomy for cervical spondylotic myelopathy and radiculopathy, in particular the outcome for patients with developmentally narrow cervical canals and patients with associated ossification of the posterior longitudinal ligament (OPLL). One hundred thirty-nine patients who had undergone anterior osteophytectomy with interbody fusion between 1976 and 1990 were followed up for 1 to 22.5 years (mean 11.4 years). Overall results evaluated by the neuroaurgical cervical spine scale scoring and grading showed significant improvement in both improvement score (2.7 ± 2.3) and improvement rate (52.3 ± 45.7%). Lower extremity motor function improved in 66.1% of patients, upper extremity motor function in 82,0%, and sensory/pain function in 70.5%. Improvement ranged from one to three grades. Severely affected patients showed good recovery. Outcome for patients with narrow cervical canals (41 patients, 29.5%) did not differ significantly from that for patients with normal canals (98, 70.5%). Patients with associated OPLL (32 patients, 23.0%) had approximately the same outcomes as those with only spondylosis (107, 77.0%). Fifteen patients (10.8%) underwent reoperation because of myelopathy due to disc degeneration adjacent to the fused level (11 patients) or OPLL (4 patients). Anterior osteophytectomy with interbody fusion can achieve good outcomes in patients with cervical spondylotic myelopathy and radiculopathy, regardless of the size of the spinal canal and association with OPLL.
- 日本脳神経外科学会の論文
- 2003-05-15
著者
-
NAKAMURA Tsutomu
Department of Hospital Pharmacy, Kobe University School of Medicine
-
Iizuka Hideaki
Department Of Neurosurgery Kanazawa Medical University
-
Kadoya Satoru
Department Of Surgery School Of Medicine University Of Kanazawa
-
Kadoya Satoru
Department Of Neurosurgery Kanazawa Medical University
-
Nakamura Tsutomu
Department Of Gastroenterological Surgery Kobe University Graduate School Of Medical Sciences
-
Nakamura Tsutomu
Department Of Chemistry Nara Womens University
-
Nakamura Tsutomu
Department Of Neurosurgery Kanazawa Medical University
-
Nakamura Tsutomu
Department Of Chemistry Faculty Of Science Faculty Of Agriculture Kyoto Unviersity
-
IIZUKA Hideaki
Department of Analytical Chemistry, Faculty of Pharmaceutical Sciences, Toho University
-
IIZUKA Hideaki
Department of Neurosurgery, Kanazawa Medical University
関連論文
- Association of Cumulative Cyclosporine Dose with Its Irreversible Nephrotoxicity in Japanese Patients with Pediatric-Onset Autoimmune Diseases(Biopharmacy)
- Reversal Effects of Ca2+ Antagonists on Multidrug Resistance via Down-regulation of MDR1 mRNA
- Three-Dimensional, but not Two-Dimensional, Culture Results in Tumor Growth Enhancement after Exposure to Anticancer Drugs
- Knock-down of Sorcin Induces Up-regulation of MDR1 in HeLa Cells(Molecular and Cell Biology)
- Effects of Reactive Oxygen Species on Cell Proliferation and Death in HeLa Cells and Its MDR1-Overexpressing Derivative Cell Line
- Effects of carvedilol on MDR1-mediated multidrug resistance : comparison with verapamil
- Effects of St John's Wort and Hypericin on Cytotoxicity of Anticancer Drugs
- Antiproliferative Activity of Rhinacanthus nasutus (L.) KURZ Extracts and the Active Moiety, Rhinacanthin C(Pharmacology)
- MDR1 T-129C Polymorphism can be Predictive of Differentiation, and Thereby Prognosis of Colorectal Adenocarcinomas in Japanese(Biopharmacy)
- Intradermal Concentration of Hydroquinone after Application of Hydroquinone Ointments Is Higher than Its Cytotoxic Concentration(Biopharmacy)
- MDR1 Haplotype Frequencies in Japanese and Caucasian, and in Japanese Patients with Colorectal Cancer and Esophageal Cancer
- MDR1 C3435T Polymorphism Is Predictive of Later Onset of Ulcerative Colitis in Japanese(Biopharmacy)
- Reversal Effects of Antifungal Drugs on Multidrug Resistance in MDR1-Overexpressing HeLa Cells
- Changes in regional cerebral blood flow in irradiated regions and normal brain after stereotactic radiosurgery
- Expression of apoptosis-related proteins (p53, p21^, bcl-2, and bax) and sensitivity to chemotherapy in squamous cell carcinoma of the esophagus
- Analysis of Postoperative Complications after Esophagectomy for Esophageal Cancer in Patients receiving Neoadjuvant Therapy
- Expression of p53 Protein Related to Human Papillomavirus and DNA Ploidy in Superficial Esophageal Carcinoma
- CT and MRI Findings of Xanthoma in the Orbitofrontal Region
- IL-1β Genotype-Related Effect of Prednisolone on IL-1β Production in Human Peripheral Blood Mononuclear Cells under Acute Inflammation(Pharmacology)
- Genetic polymorphisms associated with adverse events and elimination of methotrexate in childhood acute lymphoblastic leukemia and malignant lymphoma
- Effect of Therapeutic Moderate Hypothermia on Multi-drug Resistance Protein 1-Mediated Transepithelial Transport of Drugs
- 急性炎症下におけるヒト末梢血単核球MDR1の遺伝子型に依存した遺伝子発現量ならびに機能低下
- Comparison of Synthetic DNA Templates with Authentic cDNA Templates in Terms of Quantification by Real-Time Quantitative Reverse Transcription Polymerase Chain Reaction(Analytical Biochemistry)
- 電流検出方式DNAチップを用いた複数遺伝子型同時判定法のMDR1遺伝子への応用
- High mobility Group I-C protein in astrocytoma and glioblastoma
- Effects of Polymorphisms of MDR1, MRP1, and MRP2 Genes on Their mRNA Expression Levels in Duodenal Enterocytes of Healthy Japanese Subjects(Biopharmacy)
- Factors Influencing the Prediction of Steady State Concentrations of Digoxin
- Recurrent Meningioma With Metastasis to the Skin Incision-Case Report-
- P-gp誘導 Caco-2 細胞 : P-gp高感度 Assay System の構築
- Long-term Outcome for SUrgically Treated Cervical Spondylotic Radiculopathy and Myelopathy
- Partial esophagectomy for a superficial carcinoma arising from the mid-esophageal diverticulum
- Effects of Various Storage Conditions and Alterations of Antioxidant Contents on Chromatic Aberration of Hydroquinone Ointment(Biopharmacy)
- Effect of Serum Triglyceride Concentration on the Fluctuation of Whole Blood Concentration of Cyclosporin A in Patients
- Proapoptotic Effect of a Dietary Supplement : Water Soluble Chitosan Activates Caspase-8 and Modulating Death Receptor Expression
- Multiple Cavernous Hemangiomas of the Skull Associated With Hepatic Lesions : Case Report
- Chiasmal and/or Optic Nerve Apoplexy Due to Rupture of Vascular Malformation
- S-B-8. Side Effect of Bilateral CEM-Thalamotomy with Special Reference to Transient Distrubance of consciousness
- S-B-7. The Relation between Localization of Lesion Site and the Effect of CEM-Thalamotomy with Special Reference to Analysis of the Autopsy Cases
- 16 16. Bilateral CM Thalamotomy for Relief of Intractable Pain at One Stage : Its Effects and Side Effect (PROCEEDINGS OF THE IVth ANNUAL MEETING OF THE JAPAN SOCIETY FOR RESEARCH IN STEREOENCEPHALOTOMY)
- 57. Studies on the Genesis of Acute Pulmonary Edema after Brain Operation
- Characteristics of Chymotrypsin Modified with Water-soluble Acylating Reagents and Its Peptide Synthesis Ability in Aqueous Organic Media
- Calcification on the Ventricle Wall Associated With a Shunt Tube : Case Report
- S-2. Effect of Low Frequency Stimulation to the Nucleus Centrum Medianum and Its Vicinity,with Special Reference to Recruiting Response (Symposium:Human Depth Electrophysiology)
- 39 Effect of Hypothermia on Evoked Potentials of the Lemniscal and Extralemniscal Systems
- 15 Inhibitory Effects of the Lower Medulla Stimulation of the Evoked Potentials in the Anterolateral Fasciculus of the Spinal Cord Subsequent to the Splanchnic Nerve Stimulation
- STUDIES ON SENSORY CONDUCTION IN THE LEMNISCAL SYSTEM AND EXTRALEMNISCAL SYSTEM,DIFFUSE THALAMOCORTICAL PROJECTION SYSTEM UNDER HYPOTHERMIA
- Comparison of Extended Esophagectomy through Mini-thoracotomy/laparotomy with Conventional Thoracotomy/laparotomy for Esophageal Cancer
- De Novo Aneurysm in the Feeding Artery of a Recurrent Malignant Glioma : Case Report
- バルプロ酸誘発高アンモニア血症に対するCPS1 4217C>A遺伝子多型の影響
- MDR1 Genotype-Related Pharmacokinetics and Pharmacodynamics
- Theiler's Murine Encephalomyelitis Virus (TMEV) Subgroup Strain-Specific Infection in Neural and Non-Neural Cell Lines
- Expression of Lymphotoxin Gene Inserted into Theiler's Murine Encephalomyelitis Virus
- Alteration in the plasma concentration of a DAAO inhibitor, 3-methylpyrazole-5-carboxylic acid, in the ketamine-treated rats and the influence on the pharmacokinetics of plasma D-tryptophan
- Purification and Characterization of Recombinant Phosphoenolpyruvate Carboxylase of Thermus sp.^
- Migrated Disc in the Lumbar Spinal Canal : Case Report
- Parametric Excitation of Lower Hybrid Modes
- S-B-7. The Relation between Localization of Lesion Site and the Effect of CEM-Thalamotomy with Special Reference to Analysis of the Autopsy Cases
- Cloning and Sequence Analysis of the Gene for Phosphoenolpyruvate Carboxylase from an Extreme Thermophile, Thermus sp
- Utilization of Kynurenic Acid Produced from D-kynurenine in an in Vitro Assay of D-Amino Acid Oxidase Activity
- Primary Intracranial Melanoma : Case Report
- A case of pituitary apoplexy with spontaneous recovery.