A STUDY ON RADIOSENSITIVITY AND PROGNOSTIC FACTORS OF CERVICAL ADENOCARCINOMA
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概要
- 論文の詳細を見る
従来から子宮頚部腺癌は扁平上皮癌に比して放射線感受性が一般に不良であるとされている.しかしその理由は未だ十分には明らかにされていない.また頚部腺癌の照射に対する組織学的な障害像についても,扁平上皮癌の場合ほどには明らかにされていない.更にその治療法についても手術療法がよいのか放射線療法がよいのか,未だ結論が出されていないように思われる.著者らは教室で治療を行った分化型の頚部腺癌例を対象として,照射に対する組織学的な障害像が如何なるものであるか,腺癌の放射線感受性が不良である理由,更には腺癌の予後が扁平上皮癌に比して不良である理由などを検討し,以下の結論を得た.1.腺癌の照射効果として,核の障害,腺癌細胞の基底部からの剥離,癌胞巣の現象などが重要である.2.照射に対する腺癌細胞の経時的な減少度は著明に低く,従って腺癌の放射線感受性は扁平上皮癌に比して明らかに不良といえる.3.腺癌の予後に影響を与える重要な因子として,治療法,臨床進行期,子宮頚部の形状及び組織学的浸潤度を挙げることができる.なかでも臨床進行期が進んだ症例や,頚部の形状が直径4.5cm以上の肥大を示すか或いは深い潰瘍形成を示し,組織学的に高度の浸潤像を示す症例では,治療法の如何に拘らず予後不良といえる.
- 社団法人日本産科婦人科学会の論文
- 1980-10-01
著者
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NOGUCHI Hiroshi
Departments of Pharmacokinetics and Pharmacodynamics, Pharmacognosy and Global Center of Excellence
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Fukuta Toru
Department Of Obstetrics And Gynecology Shinshu University School Of Medicine
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Fukuta Toru
Department Of Obstetrics & Gynecology Shinshu University School Of Medicine
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TSUKAHARA Yoshiharu
Department of Obstetrics and Gynecology, Faculty of Medicine, Yamanashi Medical College
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Sakai Yoshikimi
Department Of Obstetrics Alrd Gynecology Shinshu University School Of Medicine
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IWAI Shoji
Department of Obstetrics and Gynecology, Shinshu University School of Medicine
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Tsukahara Yoshiharu
Department Of Obstetrics And Gynecology Yamanashi Medical College
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Tsukahara Yoshiharu
Department Of Obstetrics And Gynecology Shinshu University School Of Medicine Matsumoto
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Tsukahara Yoshiharu
Department Of Obstetrics And Gynecology Faculty Of Medicine Yamanashi Medical College
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Tsukahara Yoshiharu
Department Of Obstetrics & Gynecology Shinshu University School Of Medicine
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Noguchi Hiroshi
Department Of Architecture Faculty Of Engineering Chiba University
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Fukuta Toru
Department Of Obstetrics Alrd Gynecology Shinshu University School Of Medicine
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Noguchi Hiroshi
Department Of Obstetrics And Gynecology Faculty Of Medicale Shinshu University
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Noguchi Hiroshi
Department Of Anesthesiology And Acute Medicine Aichi Medical University
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Iwai Shoji
Department Of Obstetrics And Gynecology Shinshu University School Of Medicine Matsumoto
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塚原 嘉治
Department of Obstetrics and Gynecology, Faculty of Medicale, Shinshu University
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NOGUCHI Hiroshi
Deparment of Mechanical Engineering, Kyushu University
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