Linear-Shaped Motion of DNA in Entangled Polymer Solutions under a Steady Field : Cross-Disciplinary Physics
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概要
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We studied the electrophoretic behavior of DNA chains in linear-polymer solutions using Brownian dynamics with an anisotropic friction tensor. We simulated the linear-shaped motion of DNA observed in highly entangled solutions [Ueda et al.: Biophys. Chem. 71 (1998) 113] using a model with a chain segment equal to 1/4 of the persistence length. A linear conformation is seen for a chain with high segment-density regions, which remain at the same positions in space, with a high anisotropy of friction, while a U-shaped conformation is seen for a chain with a low anisotropy of friction.
- 社団法人日本物理学会の論文
- 2000-12-15
著者
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NOGUCHI Hiroshi
Departments of Pharmacokinetics and Pharmacodynamics, Pharmacognosy and Global Center of Excellence
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Takasu Masako
Department Of Applied Molecular Science
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Noguchi Hiroshi
Department Of Applied Molecular Science
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Noguchi Hiroshi
Department Of Anesthesiology And Acute Medicine Aichi Medical University
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