胆道閉鎖症(I 主要疾患の遠隔成績, 25周年記念シンポジウム論文)

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This report presents the long-term results in patients who have survived for more than 10 years after surgery for biliary atresia. Fourty-eight cases ranging in age from 10 to 33 years were examined. There were 41 cases without and 7 with jaundice. Two patients died after the age of 10 years : one died at 28 from hepatic failure caused by frequent cholangitis after operation for ileus; the other died from sudden esophageal variceal bleeding at 16. Thirty-seven (77%) of 48 cases were absolutely leading their normal lives. Among them, 6 cases were enjoying their lives after overcoming the sequelae, such as portal hypertension. Two females both aged 25 years have married, but did not become pregnant yet. The morbidities of the remaining 11 (23%) long-term survivors were jaundice in 7, portal hypertension in 5 , encephalopathy after splenorenal shunt in 1 and so on. The heights and weights of all cases except a few were comparable to those of normal Japanese. Hepatomegaly still remained in 16% and splenomegaly in 29%. The biochemical data of the serum were variable and disclosed a moderate degree of abnormality in patients complicated with postoperative cholangitis. Eleven cases including 6 jaundiced cases required treatment for esophageal varices and hypersplenism. In conclusion, although the long-term survivors with persistent jaundice develop sequelae that require some kinds of treatment, the cured states of most cases without jaundice are satisfactory and eventually these former patients can achieve a favorable quality of life.
日本小児外科学会の論文
1989-10-20

胆道閉鎖症(I 主要疾患の遠隔成績, 25周年記念シンポジウム論文)

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