乳児期より甲状腺機能亢進症を呈した腺腫様甲状腺腫の1例

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We operated on a 5-year-old girl with adenomatous goiter and hyperthyroidism. The patient had delayed growth and a large goiter since the age of 6 monthsold, when the serum level of thyroid iodine was high, and the diagnosis of hyperthyroidism was made. Treatment with propylthiouracil (PTU) was started. Circulating thyroid antibodies and long-acting thyroid stimulator (LATS) were not detected. The patient continued to require PTU in order to remain euthyroid. At the age of 5 yearsold, the goiter enlarged and became nodular, so subtotal thyroidectomy was done. The diagnosis of adenomatous goiter was made. The postoperative course was uneventful. One year and 10 months after the operation, the patient remains euthyroid without medication. The majority of patients with adenomatous goiter are adults and are clinically euthyroid. Infants with hyperthyroidism associated with adenomatous goiter are very rare.
日本小児外科学会の論文
1988-02-20