小児ファロー四徴症根治術に於ける心筋保護法の評価

概要

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The effect of myocardial protective method on the post operative hemodynamic was studied in two groups of patients with Tetralogy of Fallot (TOF) who had a radical operation. Twenty Four TOF patients were divided into two groups based on Crystalloid Cardioplegia (group A) or non Crystalloid Cardioplegia (group B). The Crystalloid Cardioplegic Solution was made of 500ml of 5% glucose to which we added 10 mEq of sodium bicarbonate and 10 mEq of potassium chlorid. This solution was kept at 4 to 6℃. The pH of this solution was 8.322, and the milliosmolarity was 327. At 3 hrs after operation, LVWI showed higher Cardiac Pump-Function in the group A than group B. It was not different for the postoperative pleural effusion between the two groups in those cases with a patch size of 10cm^2/m^2 or larger, however the incidence of postoperative pleural effusion was somewhat smaller for those cases with a patch size of less than 10cm^2/m^2, particularly so in the cardioplegic solution group. The mortality rate in A group was 7.6%, and in B group 18.1%.
日本小児外科学会の論文
1985-05-20