肝間葉性過誤腫の1治験例 : 本邦報告例と対比して

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An eight month old male infant was admitted with an abdominal mass located in the upper abdomen, which was noted a month prior to admission. On admission, the laboratory significances were SGOT 31mU/ml, LDH 171mU/ml and alfa-fetoprotein 3200ng/ml. The findings of liver scintigram and angiogram suggested a hepatoblastoma or mesenchymal hamartoma in the right lobe of the liver. A laparotomy was undertaken and a right hepatic lobectomy was successfully performed including the total excision of the tumor. The tumor was in a pedunculate fashion attached to the lower surface of the right lobe of the liver. The excised mass measured 16.5 by 14.0 by 8.0cm and weight 1320gm. Histological findings were characteristic of mesenchymal hamartoma, including loose myxomatous mesencym with proliferation of the ductal structure which is similar to the interlobular bile ducts, and an expansive growth to compress the surrounding liver tissue. There was no problem during the immediate postoperative period and the patient has been uneventful for the last 15 months after operation. This is the 18th reported case of mesenchymal hamartoma of the liver in Japan. By the survey of the other reported cases, alfa-fetoprotein was elevated in 4 out of 6 cases in which the determination was carried out. As seen in these four reported cases, alfa-fetoprotein reduced to the normal value one month after operation in our patient. It is interesting that there is an elevation of alfa-fetoprotein in this tumor.
日本小児外科学会の論文

肝間葉性過誤腫の1治験例 : 本邦報告例と対比して

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