初回の pH score で GER を否定した症例のその後 : pH score の信頼性について

概要

論文の詳細を見る
From 1979 to 1988, 159 infants and children with symptoms of gastroesophageal reflux (GER), were evaluated 231 times by pH score, which was the sum of the scores of the percentage time of the pH below 4 and the number of refluxes persisted over a 5-min period. GER in 77 patients was ruled out by a result of initial pH score. During one to six years after initial evaluation, seven patients developed symptoms of GER and other 69 had no symptoms of GER. Seven were diagnosed as GER after reexamination. No reflux was monitored in another patient of tight esophageal stricture with hiatus hernia, but diagnosis of GER was apparent. Three of eight were managed conservatively and five underwent Nissen fundoplication. The clinical characteristics of these patients were newborn, clild suffering from respiratory complications and severely rearded child. The rate of false negative patient in diagnosing GER with initial pH score alone was 8.9 percent, but diagnostic accuracy of the pH score was 99.4 percent when the test was repeated.
日本小児外科学会の論文
1991-10-20