An Analytic Formula for the Concentration Profile of Secreted Molecules in Intercellular Signaling : A Case of Non-Uniform Secretion Rate in Magnitude and Direction
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概要
- 論文の詳細を見る
An analytic formula is established for the concentration profile of secreted molecules by solving the diffusion equation in the case of a time-dependent secretion rate with non-uniformity in its magnitude and direction. It is explicitly shown that the concentration exhibits a significant angular dependence in a region near the secreting cell. The formula is applied to estimate the non-uniform secretion effect on an effective communication distance for human cytokines in intercellular signaling.
- 社団法人日本物理学会の論文
- 2003-03-15
著者
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Huang Shiping
College Of Chemical Engineering Beijing University Of Chemical Technology
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Yoshida F
Department Of Physics Shiga University Of Medical Science
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Yoshida Fukuo
Department Of Physics Shiga University Of Medical Science
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Horiike Kihachiro
Dept Biochem Mol Biochem, Shiga Univ Med Sci
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Horiike K
Dept Biochem Mol Biochem Shiga Univ Med Sci
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Horiike Kihachiro
Department Of Biochemistiy Shiga University Of Medical Science
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