Communication distance in the intercellular signaling by cyto/chemokine or autacoid
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概要
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Characteristic properties of signaling processes are studied by a single cell model in the intercellular transport. The diffusion equation is solved for molecules secreted from a spherical cell under the boundary conditions of prescribed fluxes at the cell surface. The solution is physicochemically compared with another one corresponding to constant source at the cell surface by Francis and Palsson. 1) Discussion is given on communication distances (-50μm) estimated for human cytokines.
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著者
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Yoshida Fukuo
Department Of Physics Shiga University Of Medical Science
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Horiike Kihachiro
Department Of Biochemistiy Shiga University Of Medical Science
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