LACK OF ADRENOCORTICAL HORMONE-LIKE EFFECTS OF CHLORMADINONE ACETATE IN GUINEA PIGS

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概要

• 論文の詳細を見る

• Treatment with 0.01, 0.1 and 1.0% chlormadinone acetate (CMA) contained diets for 33 days to guinea pigs showed no signs of the depression in adrenal, thymus and leucocyte count and no elevation of serum cholesterol. By the treatment with 0.01 and 0.1% cortisol contained diets, however, the atrophy of adrenal and thymic cortex, hypercholesterolemia and the enlargement of liver were noted in this species. It was therefore concluded that CMA had no cortisone-like properties in guinea pigs even at the excessive doses.

• 日本トキシコロジー学会の論文
• 1977-04-15

著者

• Horiuchi Toshi

  Safety Resarch Department, Teikoku Hormone Mfg Co., Ltd.

• ITO Kiyoko

  Safety Research Department, Teikoku Hormone Mfg.Co.Ltd.

• Ito Kiyoko

  Toxicological Research Department Teikoku Hormone Mfg.co.ltd.

• Ito Kiyoko

  Safety Research Department Teikoku Hormone Mfg.co.ltd.

• Horiuchi Toshi

  帝国臓器製薬

• Horiuchi Toshi

  Toxicological Research Department Teikoku Hormone Mfg.co.ltd.

• Horiuchi Toshi

  Safety Resarch Department Teikoku Hormone Mfg Co. Ltd.

• Masuda Shuji

  Pharmacologicl Research Department Teikoku Hormone Mfg. Co.. Ltd.

• Nakayama Takaharu

  Pharmacologicl Research Department Teikoku Hormone Mfg. Co.. Ltd.

• HORIUCHI Toshi

  Pharmacologicl Research Department, Teikoku Hormone Mfg. Co.. Ltd.

• MAKINO Masao

  Pharmacologicl Research Department, Teikoku Hormone Mfg. Co.. Ltd.

• ITO Kiyoko

  Pharmacologicl Research Department, Teikoku Hormone Mfg. Co.. Ltd.

• KUBOAKI Hiroyoshi

  Pharmacologicl Research Department, Teikoku Hormone Mfg. Co.. Ltd.

• TAKAHASHI Hiroo

  Pharmacologicl Research Department, Teikoku Hormone Mfg. Co.. Ltd.

• SUZUKI Minoru

  Pharmacologicl Research Department, Teikoku Hormone Mfg. Co.. Ltd.

• Suzuki Minoru

  Department Of Applied Biological Chemistry Graduate School Of Agricultural And Life Sciences The Uni

• Suzuki Minoru

  Safety Resarch Department Teikoku Hormone Mfg Co. Ltd.

• Makino Masao

  Toxicological Research Department Teikoku Hormone Mfg.co.ltd.

• Suzuki Minoru

  Toxicological Research Department, Teikoku Hormone Mfg.Co.Ltd.

• Kuboaki Hiroyoshi

  Pharmacologicl Research Department Teikoku Hormone Mfg. Co.. Ltd.

• Takahashi Hiroo

  Pharmacologicl Research Department Teikoku Hormone Mfg. Co.. Ltd.

• Suzuki Minoru

  Toxicological Research Department Teikoku Hormone Mfg.co.ltd.

• Suzuki Minoru

  Safety Research Department Teikoku Hormone Mfg.co.ltd.

• TAKAHASHI Hiroo

  Pharmacological Research Department, Teikoku Hormone Mfg. Co. Ltd.

• MAKINO Masao

  Pharmacological Research Department, Teikoku Hormone Pharmaceutical Company

• MAKINO Masao

  Pharmacological Research Department, Teikoku Hormone Mfg. Co., Ltd.

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