Evaluation of the Risk of Drug-Induced Long QT Syndrome : Electrophysiological Analysis Using Native Cardiac Cells and Cultured Cells Expressing HERG Channels(SEMINAR 1 : MODELS FOR PROFILING THE POTENTIAL QTc PROLONGATION RISK OF A DRUG (ICH-57B)ICH SAFE
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概要
著者
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NAKAYA Haruaki
Department of Pharmacology, Chiba University Graduate School of Medicine
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Nakaya Haruaki
Department Of Pharmacology Chiba University Graduate School Of Medicine
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Nakaya Haruaki
Department Of Orthopaedic Surgery And Pharmacology School Of Medicine Chiba University
関連論文
- Glimepiride Treatment Upon Reperfusion Limits Infarct Size via the Phosphatidylinositol 3-Kinase/Akt Pathway in Rabbit Hearts
- FRS-009 Crucial roles of PDK1 in the regulation of β-adrenergic response and cell survival in the hearts(Novel Pathophysiological Mechanisms of Heart Failure(M),Featured Research Session,The 72nd Annual Scientific Meeting of the Japanese Circulation Socie
- OE-056 Erythropoietin Prevents LV Remodeling after Myocardial Infarction through Erythropoietin Receptor-Induced Signaling Pathways in the Heart(Acute myocardial infarction, basic-1, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-242 Erythropoietin Has an Ischemic Postconditioning-like Effect on Myocardium through a Direct Action on Cardiomyocytes(Myocardial ischemia-reperfusion, basic/clinical-2 (M) OJ41,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeti
- The Direct Effects of G-CSF on Cardioprotection against Ischemia/Reperfusion Injury(Myocardial Ischemia-reperfusion, Basic 3 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Optimal Treatment Strategy for Patients With Paroxysmal Atrial Fibrillation : J-RHYTHM Study(Arrhythmia/Electrophysiology)
- New Aspects for the Treatment of Cardiac Diseases Based on the Diversity of Functional Controls on Cardiac Muscles : Mitochondrial Ion Channels and Cardioprotection
- OJ-241 Adrenomedullin Potentiates the Opening of Mitochondrial Ca^-Activated K^+ Channels and Reduces Infarct Size in Rabbit Hearts(Myocardial ischemia-reperfusion, basic/clinical-2 (M) OJ41,Oral Presentation (Japanese),The 70th Anniversary Annual Sci
- OJ-241 Adrenomedullin Potentiates the Opening of Mitochondrial Ca^-Activated K^+ Channels and Reduces Infarct Size in Rabbit Hearts(Myocardial ischemia-reperfusion, basic/clinical-2 (M) OJ41,Oral Presentation (Japanese),The 70th Anniversary Annual Sci
- FRS-009 Crucial roles of PDK1 in the regulation of β-adrenergic response and cell survival in the hearts(Novel Pathophysiological Mechanisms of Heart Failure(M),Featured Research Session,The 72nd Annual Scientific Meeting of the Japanese Circulation Socie
- OJ-242 Erythropoietin Has an Ischemic Postconditioning-like Effect on Myocardium through a Direct Action on Cardiomyocytes(Myocardial ischemia-reperfusion, basic/clinical-2 (M) OJ41,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeti
- Effects of Antiarrhythmic Drugs on the Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel Current
- FRS-069 PDK-1 Plays Essential Roles in Cell Size Regulation, Beta-adrenergic Response and Cell Survival in the Heart(Heart Failure, Cardiac Remodeling and Cardiomyopathy 1, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PE-569 Brown Adipose Tissue Derived-cells Differentiate into Spontaneous Beating Cells with both Cardiac Conduction and Pace-maker Characters(Regeneration (angiogenesis/myocardial regeneration)-4, The 71st Annual Scientific Meeting of the Japanese Circula
- Altered deactivation kinetics modify the inhibitory effects of class III antiarrhythmic drugs on HERG channel
- Vasopressin V_1 - Receptor Stimulation Produces a Positive Inotropic Response without Affecting pH_i in Guinea Pig Papillary Muscles
- Evaluation of the Risk of Drug-Induced Long QT Syndrome : Electrophysiological Analysis Using Native Cardiac Cells and Cultured Cells Expressing HERG Channels(SEMINAR 1 : MODELS FOR PROFILING THE POTENTIAL QTc PROLONGATION RISK OF A DRUG (ICH-57B)ICH SAFE
- Effects of Azimilide on the Muscarinic Acetylcholine Receptor-Operated K^+ Current and Experimental Atrial Fibrillation in Guinea-Pig Hearts
- Sarcolemmal ATP-sensitive K^+ channels and cardiovascular function
- Effects of Nicorandil on the cAMP-Dependent Cl− Current in Guinea-Pig Ventricular Cells
- FRS-171 Role of Na+-Ca2+ Exchanger in Myocardial Ischemia/Reperfusion Injury : Evaluation Using a Heterozygous Na+-Ca2+ Exchanger Knockout Mouse Model(Coronary Heart Disease : Basic Science (IHD) : FRS20)(Featured Research Session (English))
- Effects of lipo-prostaglandin E_1 on blood flow and oxygen pressure in lumbo-sacral nerve roots
- Effects of Bepridil and Amiodarone on Ouabain-Induced Mitochondrial Ca^ Overload in Guinea-Pig Ventricular Cells
- Ischemia-induced electrophysiological alterations in the heart of Kir6.2-deficient mice
- Minoxidil sulfate confers cardioprotection via activation of mitochondrial K_ channels in guinea-pig ventricular myocytes
- ATP-Sensitive K^+ Channel Modulates the Secretion of Atrial Natriuretic Peptide : A Study Using Kir6.2-Deficient Mice (Excitation-contraction Coupling/Ion Channel 2 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Inhibition of ATP-Sensitive K+ Channels and L-Type Ca2+ Channels by Amiodarone Elicits Contradictory Effect on Insulin Secretion in MIN6 Cells
- Effects of Nicorandil on the cAMP-Dependent Cl^- Current in Guinea-Pig Ventricular Cells
- Effects of GABAergic Drugs on the Recovery of Reflex Potentials after Spinal Cord Ischemia in Cats
- EFFECTS OF VARIOUS DRUGS ON CONDUCTION DELAY INDUCED BY ACUTE MYOCARDIAL ISCHEMIA IN DOGS : Arrhythmia II : IInd Auditorium : Proceedings of the 43rd Annual Meeting of the Japanese Circulation Society, Tokyo, 1979
- QT PRODACT : Database Construction for the Evaluation of the Risk of QT Interval Prolongation by Drugs in Japan
- PE-357 NS1619 Opens the Mitochondrial Calcium-Activated K^+ Channels and Attenuates the Mitochondrial Ca^ Overload in Guinea-Pig Ventricular Cells(Cardiovascular Pharmacology, Basic/Clinical 4 (H) : PE61)(Poster Session (English))
- Cardioprotective effect of diazoxide is mediated by activation of sarcolemmal ATP-sensitive potassium channels in mouse model
- Inhibition of ATP-Sensitive K^+ Channels and L-Type Ca^ Channels by Amiodarone Elicits Contradictory Effect on Insulin Secretion in MIN6 Cells
- Novel Antiarrhythmic Drugs for the Treatment of Atrial Fibrillation : Current Perspective
- Electropharmacological Profiles of NTC-801, a Novel Selective Acetylcholine-Activated K+ Channel Blocker
- Antiarrhythmic Effects of NTC-801, a Selective Acetylcholine-Activated K+ Channel Blocker, on Experimental Atrial Fibrillation
- Pharmacological Treatment of Atrial Fibrillation: An Overview
- Frequency- and voltage-dependent depression of maximum upstroke velocity of action potentials by primenol in guinea pig ventricular muscles.
- Suppression of lysophosphatidylcholine-induced abnormal automaticity by verapamil in canine Purkinje fibers.
- Does Anti-Inflammatory Action of Amiodarone Explain the High Efficacy in Patients With Heart Failure?
- Tonic Block of the Sodium and Calcium Currents by Ketamine in Isolated Guinea Pig Ventricular Myocytes.