当院における病棟分離菌の薬剤感受性と抗生物質の使用状況

概要

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We investigated the sensitivity of clinical isolates of bacterial strains to antibiotics and the amount of antibiotics dispensed for inpatients in each ward of our hospital. In the surgery ward, Bactericides sp., E. coli, P.aeruginosa and S.aureus were frequently isolated, and cephem antibiotics and piperacillin sodium (PIPC) were mainly used, while many isolates were resistant to PIPC. In the neurosurgery ward, frequent isolates were S.aureus, P.aeruginosa, S.epidermidis. In the internal and cardiovascular medicine ward, P.aeruginosa, S.aureus, K.pneumoniae and S.epidermidis were frequent isolates. In these wards, imipenem/cilastatin sodium (IPM/CS) and cephem antibiotics were mainly used, although most isolates of S.aureus were resistant to these drugs. In the urology ward, Enterococcus sp. and P.aeruginosa were frequently isolated, whereas cephem antibiotics which were ineffective to these isolates were mainly used. The frequent isolates which were resistant to cephem drugs or IPM/CS probably resulted from the frequent use of these drugs. Considering the present results, choice of antibiotics should be more discussed.
日本医療薬学会の論文
1992-03-20