病院薬剤師業務のさらなる展開に向けて : 外来乳癌患者における副作用自己モニタリングの試み

概要

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In the present study, we implemented the self-monitoring of side effects in surgical outpatients with breast cancer to improve their quality of life (QOL). Self-monitoring of side effects was carried out by entering the early symptoms (myelosuppression and gastrointestinal failures) on a specially prepared side effect checkingsheet. Six outpatients participated in this study. The chemotherapeutic regimens consisted of cyclophosphamide, adriamycin and 5-fluorouracil, i.e. CAF therapy. In these patients, a mild myelosupression was after the complection of half of each protocol (from approximately day 8 to 14). However, there was seen was no relationship between the early symptoms of myelosupression ("fever", "general fatigue" and "throat pain" score) and the number of leucocytes. On teh other hand, the self-monitoring of side effects showed a better influence on the subjective sceore for the symptoms of gastrointestinal failures (i.e. "nausea"). In the present study, the self-monitoring of side effects in outpatients withe breast cancer was thus suggested to be a useful tool for improving the patient's QOL.
日本医療薬学会の論文
2001-06-10