Relative Sparing of Calcitonin Gene-Related Peptide-Containing Primary Sensory neurons Following Neonatal Capsaicin Treatment in the Rat

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概要

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• KASHIBA, H., E. SENBA, Y. UEDA AND M. TOHYAMA Relative sparing of calcitonin gene-related peptide-containing primary sensory neurons following neonatal capsaicin treatment in the rat. PEPT1DES 11(3)491-496, 1990. -Calcitonin gene-related peptide (CGRP)-containing sensory neurons projecting to viscera or skin were detected by immunocytochemistry combined with fluorescent tracer in the dorsal root ganglia (Th9-10) of rats 5-6 weeks old treated neonatally with capsaicin. The number of CGRP-like immunoreactive (IR) cells were reduced by 50-60% with capsaicin treatment. Visceral CGRP-IR sensory neurons were shown to be more sensitive than cutaneous ones, which was also supported by the fact that CGRP-IR fibers in the stomach were completely diminished while epidermal CGRP-IR fibers were spared.

• 関西鍼灸大学の論文
• 1991-04-01

著者

• UEDA Yoshihiro

  Department of Astronomy, Kyoto University

• Tohyama Masaya

  Department of Anatomy, Osaka University Medical School

• SENBA Emiko

  Department of Neuroanatomy, Institute of Higher Nervous Activity, Osaka University Medical School

• Ueda Yoshihiro

  Department Of Physiology Kansai College Of Acupuncture Medicine

• Ueda Yoshihiro

  Department Of Applied Biological Chemistry The University Of Tokyo

• Kashiba Hitoshi

  Department of Physiology, Kansai College of Acupuncture Medicine

• Tohyama Masaya

  Department Of Anatomy (ii) Osaka University Medical School

• Kashiba Hitoshi

  Department Of Applied Physiology Osaka University Of Health And Sport Sciences:department Of Physiol

• Senda Emiko

  Department Of Anatomy (ii) Osaka University Medical School:department Of Anatomy (ii) Wakayama Medic

• Senba Emiko

  Department Of Anatomy And Neurobiology Wakayama Medical College

• UEDA YOSHIHIRO

  Department of Physiology, Kansai College of Acupuncture Medicine

• SENBA Emiko

  Department of Anatomy & Neurobiology, Wakayama Medical University

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