<原著論文>高齢者冠状動脈バイパス術の検討〜術後重要臓器障害における加齢の関連性〜

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Objectives: The effects of aging on mortality and morbidity after coronaryartery bypass grafting (CABG) are not clear at present. To clarify these effects,we investigated the change of organ function perioperatively in patients undergoingCABG.Materials and Methods: We investigated the clinical course, including cardiac,renal, liver and respiratory functions in the pre- and postoperative periods of 135patients. The patients were divided into four age-dependent groups (Group A, 26patients aged under 59; Group B, 44 patients aged 60-69; Group C, 56 patients aged 7079;and Group D, 9 patients aged over 80) and then were compared by the parametersdescribed above.Results: The mortality rate was 1.48% for all patients. In the preoperative period,there was no significant difference between the four groups in terms of cardiac index,SvOz, GOT, GPT, or T.Bil. Respiratory function (PaO,/FiO,) was significantly (p <0.05) lower in group D than in the other groups. Creatinine clearance tended to be lowerin Group D than in the other groups. After CABG, the BUN and Cre increased andPaOz/FiOz decreased from the preoperative levels in all the groups. The CRP normalizationperiod, the intubation time, and the duration of ICU stay and hospitalization werelonger in Group D than in the other groups.Conclusions: Aging exerted a decreased function on the postoperative respiratoryand renal functions with a concomitant prolongation of CRP normalization. Thus, inelderly patients undergoing CABG with extracorporeal circulation, greater medicalattention to respiratory and renal dysfunction should be given perioperatively.
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<原著論文>高齢者冠状動脈バイパス術の検討〜術後重要臓器障害における加齢の関連性〜

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<原著論文>高齢者冠状動脈バイパス術の検討 〜術後重要臓器障害における加齢の関連性〜

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<原著論文>高齢者冠状動脈バイパス術の検討〜術後重要臓器障害における加齢の関連性〜