Protein Kinase C Inhibits G protein-gated Inwardly Rectifying K^+ Channels

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概要

• 論文の詳細を見る
• 名古屋大学の論文

著者

• Lee Jong-kook

  Division Of Cardiovascular Research Research Institute Of Environmental Medicine Nagoya University

• Lee Jong-kook

  山口大学 医学系研究科器官病態内科学循環器内科

• ZHANG Liyan

  Department of Circulation Research Institute of Environmental Medicine, Nagoya University

• Lee Jong-kook

  Department Of Circulation Research Institute Of Environmental Medicine Nagoya University

• Zhang Liyan

  名古屋大学 心研

• Zhang L

  Department Of Circulation Research Institute Of Enviromental Medicine Nagoya University

• Lee Jong-kook

  Department Of Cardiovascular Research R.i.e.m. Nagoya University

• Lee Jong-kook

  Research Institute Of Environmental Medicine Nagoya University

関連論文

• PJ-113 Nkx2.5(+) But Not Flk1(+) Cardiac Progenitor Cells are Fated to Pacemaker Cells Expressing I_f Predominantly Encoded by HCN4 Gene(Heart failure, basic(05)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation So
• Developmental Changes of Ni^ Sensitivity and Automaticity in Nkx2.5-Positive Cardiac Precursor Cells From Murine Embryonic Stem Cell
• Effects of Aldosterone on Cx43 Gap Junction Expression in Neonatal Rat Cultured Cardiomyocytes
• Decreased Vagal Control Over Heart Rate in Rats With Right-Sided Congestive Heart Failure : Downregulation of Neuronal Nitric Oxide Synthase
• Pre- and Post-ganglionic Vagal Control of Heart Rate in Rats with Right Ventricular Heart Failure
• 〈SHORT REPORTS〉Adenovirus-mediated Gene Transfer of Wild-type
• Promoted Cell Surface Expression of Heteromeric G-Protein-gated K^+ Channels in Human Embryonic Kidney(HEK)293 Cells
• PJ-200 Aldosterone Modulated Gap Junction Remodeling through Mineralocorticoid Receptor(Arrhythmia, basic(05)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PE-328 Heavy Ion Radiation Upregulates Connexin43 and Ameliorates the Substrates for VT/VF in Rabbit Hearts after Myocardial Infarction(Arrhythmia, basic-4 (A) PE55,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Ci
• Combined Effects of Nifekalant and Lidocaine on the Spiral-Type Re-Entry in a Perfused 2-Dimensional Layer of Rabbit Ventricular Myocardium
• Electrical Inhomogeneity and Instability of Rabbit Ventricles after Non-Transmural Myocardial Infarction : A High-Resolution Optical Mapping Analysis(Arrhythmia, Basic 2 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Heavy Ion Radiation Ameliorates the Substrates for VT/VF in Rabbit Hearts after Myocardial Infarction(Arrhythmia, Basic 1 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-035 Aldosterone is an Important Arrhythmogenic Substrate by Modulating the Gap Junction Channel Protein Connexin43(Arrhythmia, basic-5, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-034 T-type Ca^ Channel Modulates Gap Junction Remodeling through Renin-Angiotensin-Aldosterone System(Arrhythmia, basic-5, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PE-129 Aldosterone Modulates Gap Junction Remodeling in Cultured Rat Ventricular Myocytes(Arrhythmia, basic-3 (A) PE22,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-199 GDNF Acts as a More Potent Chemoattractant than NGF for Sympathetic Innervation in Cultured Ventricular Myocytes(Arrhythmia, basic(05)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• Long-term Effects of Amiodarone on T3-responsive Gene Expression Profiles in the Rat Heart, Liver and Pituitary(Arrhythmia, Basic 3 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Long-term Effects of Amiodarone and its Non-iodinated Analogue, Dronedarone, on the Transcription of Cardiac Sarcoplasmic Reticulum Ca^2+-ATPase Gene
• PJ-556 Intercellular Uncoupling Stabilizes Spiral-wave Reentry in Favor of its Persistence(PJ093,Ventricular Arrhythmia (Clinical/Diagnosis/Treatment) 2 (A),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• FRS-020 Reconstitution of cardiac pacemaker sheets by the patterning of cell alignment using magnetic nanoparticles(New Insights into Basic Mechanism of Arrhythmia(A),Featured Research Session,The 72nd Annual Scientific Meeting of the Japanese Circulation
• Pathophysiological Significance of T-type Ca^ Channels : Expression of T-type Ca^ Channels in Fetal and Diseased Heart
• [SHORT REPORTS]Chenges in the Membrane Currents of Rat Myocytes in Association with Right Ventricular Hypertrophy
• OJ-157 MK Gene Transfer Causes Amelioration of Cardiac Remodeling after Myocardial Infarction through Enhancements of Neovascularization and Cell Survival(OJ27,Coronary Circulation/Chronic Coronary Disease (Basic/Clinical) (IHD),Oral Presentation (Japanes
• OE-424 Patterned Cell Alignment Using Magnetite Nanoparticles to Prevent Arrhythmogenicity of Skeletal Myoblast Transplantation(OE72,Arrhythmia, Mechanism (A),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Socie
• PE-546 Midkine Plays and Angiogenetic Action through an Activation of Akt(Peripheral circulation/Vascular disease-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OE-269 Bepridil Reduces Dilatation-induced Vulnerability to Atrial Fibrillation in Rabbit Hearts through Prevention of Refractory Period Shortening and Heterogeneous Intraatrial Conduction(Arrhythmia, basic-2, The 71st Annual Scientific Meeting of the Jap
• FRS-014 Adenoviral Overexpression of Midkine Prevents the Left Ventricular Remodeling and Preserves the Cardiac Function after Myocardial Infarction(Cardiac Function "Ventricular Mechanics and Calcium Handling", The 71st Annual Scientific Meeting of the J
• PE-298 Feasibility of Undifferentiated ES Cell Engraftment to Diseased Hearts is Limited by Tumorigenesis and Apoptosis through Leukemia Inhibitory Factor (LIF)(Regeneration (angionenesis/myocardial regeneration)-5 (M) PE50,Poster Session (English),The 70
• OJ-160 Midkine Prevents the Cardiac Remodeling in Mice after Myocardial Infarction and Improves their Long-term Survival(Chronic coronary heart disease/Remodeling-2 (IHD) OJ27,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of
• Subtype Switching of L-Type Ca^ Channel From Ca_v1.3 to Ca_v1.2 in Embryonic Murine Ventricle
• De-differentiation is a mechanism of electrical-remodeling in diseased hearts
• 〈SHORT REPORTS〉Mechanosensitivity of G Protein-activated K^+
• OE-083 Midkine Ameliorates Ischemia/Reperfusion Injury of Cardiac Muscle through a Reduction of Apoptotic Reaction(Myocardial Ischemia-Reperfusion, Basic and Clinical 1 (IHD) : OE10)(Oral Presentation (English))
• Down-regulation of Connexin 43 mRNA in Mouse Hearts after Myocardial Infarction
• Overexpression of Calpastatin by Adenovirus-Mediated Gene Transfer Prevents Reperfusion Injury in the Rat Heart
• Altered I_f Channel Gene Expression in Mouse Hearts after Myocardial Infarction
• Overexpression of Calpastatin Ameliorates Functional Recovery from Ischemic Injury in the Rat Heart
• OE-134 Gene profiling in a novel mouse model of acquired QT prolongation and Torsade de Pointes secondary to complete AV block(Arrhythmia, Basic 4 (A) : OE16)(Oral Presentation (English))
• -0637- TIME COURSES OF CHANGES IN TRANSIENT OUTWARD CURRENT IN RAT VENTRICULAR MYOCYTES WITH MONOCROTALINE INDUCED PULMONARY HYPERTENSION(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY)
• 1 Structural Remodeling in Atrail Fibrillation as Arrhythmogenic Substrates : Tachyarrhythmia and Gap Junction Remodeling(Plenary Session 3 (PL3) (A) : Atrial Fibrillation : From bench to bedside)(Special Program)
• IS023 Cell-cell communication prevents apoptosis of cultured myocytes
• Pathophysiological Significance of T-type Calcium Channels: Expression of T-type Ca2+ Channels in Fetal and Diseased Heart
• OJ-024 Cav1.3 (α_) Subunit Underlies the Functional L-type Ca^ Channels in the Mouse Early Embryonic Hearts(Excitation-Contraction Coupling/Ion Channel (A) : OJ3)(Oral Presentation (Japanese))
• T-type Ca Channel Blockers Prevent Cardiac Cell Hypertrophy through an Inhibition of NFAT-3 Activation (Cardiac Hypertrophy, Basic (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Recapturation of Early Embryonic T-Type Ca^ Channel Genes (α 1h) in Mouse Remodeled Hearts after Myocardial Infarction
• Developmental changes of mRNA subtypes for the L-type Ca^ channel in the mouse heart
• A Novel Approach to Treat Complete Atrio-ventricular (AV) Block by Transplantation of Embryonic Stem Cell-derived cardiac cells(Arrhythmia, Basic (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• OE-130 Long-term cardiac effects of desethylamiodarone (DEA) are mediated by an inhibition of T3 action on the nuclear thyroid hormone receptor(Arrhythmia, Basic 4 (A) : OE16)(Oral Presentation (English))
• Paracrine Factors from Cultured Cardiac Cells Promote Differentiation of Embryonic Stem Cells into Cardiac Myocytes
• Electrophysiological Differentiation of Cardiac Myocytes Derived from Nkx2.5-GFP Knock-In Murine Embryonic Stem Cell and Their Functional Coupling with Native Myocytes
• Optimal Population of Embryonic Stem Cells in "Hanging Drop" Culture for in-vitro Differentiation to Cardiac Myocytes
• Regulation of spontaneous activity in mouse ventricular myocytes by gene transfer of the inwardly rectifying K (Kir2.2) channel
• Mechanosensitivity of GIRK Channels Depends on Channel-PIP_2 Interactions(RIEM Conference II, 2002)
• Mechanosensitivity of G Protein-Activated Inwardly Rectifying K^+ (GIRK) Channels Depends on Channel-PIP_2 Interactions throughthe Activation of PKC
• Molecular Mechanisms for Regulation of the G Protein-activated Inwardly Rectifying K^+ (GIRK) Channels by Protein Kinase C
• PKC-dependent Modulation of GIRK4 Subunit is Involved in the Mechanosensitivity of G protein-activated K_+ Channels
• Protein Kinase C Inhibits G protein-gated Inwardly Rectifying K^+ Channels
• Development of Spatially Separated Coculture System of the Sympathetic Neuron and the Cardiomyocyte
• EFFECTS OF ELECTRICAL STIMULATION ON BEATING RHYTHM OF CULTURED VENTRICULAR MYOCYTES

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