Molecular Mechanisms for Regulation of the G Protein-activated Inwardly Rectifying K^+ (GIRK) Channels by Protein Kinase C

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概要

• 論文の詳細を見る

• 国立情報学研究所で電子化したコンテンツを使用している。

• 名古屋大学の論文

著者

• Kodama Itsuo

  Department of Cardiovascular Research, Research Institute of Environmental Medicine, Nagoya Universi

• Lee Jong-kook

  Division Of Cardiovascular Research Research Institute Of Environmental Medicine Nagoya University

• Lee Jong-kook

  山口大学 医学系研究科器官病態内科学循環器内科

• Lee Jong-kook

  Department Of Cardiovascular Research Research Institute Of Environmental Medicine Nagoya University

• ZHANG Liyan

  Department of Circulation Research Institute of Environmental Medicine, Nagoya University

• Lee Jong-kook

  Department Of Circulation Research Institute Of Environmental Medicine Nagoya University

• Zhang Liyan

  名古屋大学 心研

• Zhang L

  Department Of Circulation Research Institute Of Enviromental Medicine Nagoya University

• Lee Jong-kook

  Department Of Cardiovascular Research R.i.e.m. Nagoya University

• Lee Jong-kook

  Research Institute Of Environmental Medicine Nagoya University

• Kodama Itsuo

  Department Of Cardiovascular Research R.i.e.m. Nagoya University

• Zhang Liyan

  Department Of Circulation Research Institute Of Enviromental Medicine Nagoya University

関連論文

• OE-425 Changes of Adhesion Junctions Precede the Gap Junction Remodeling during the Development of Heart Failure(OE72,Arrhythmia, Mechanism (A),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• Virtual Electrode-induced Spiral Reentry in Ventricular Myocardium Perfused in-vitro
• Na^+ Channel Blockade Causes a Prolongation of Electrical Diastole during Spiral-type Reentry in the Ventricle
• Japanese Randomized Trial for Investigation of a Combined Therapy of Amiodarone and Implantable Cardioverter Defibrillator in Patients With Ventricular Tachycardia and Fibrillation : The Nippon ICD Plus Pharmacologic Option Necessity (NIPPON) Study Design
• Effects of Aldosterone on Cx43 Gap Junction Expression in Neonatal Rat Cultured Cardiomyocytes
• Decreased Vagal Control Over Heart Rate in Rats With Right-Sided Congestive Heart Failure : Downregulation of Neuronal Nitric Oxide Synthase
• Virtual Electrode Polarization-Induced Reentrant Activity
• Functional roles of I_ and I_ on spatial and frequency-dependent modulation of repolarization in ventricular myocytes
• EFFECTS OF [K^+]_0 ON ANISOTROPIC CONDUCTION PROPERTIES OF CANINE VENTRICULAR MUSCLES : PROCEEDINGS OF THE 47th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY : Electrophysiology (I)
• Disorganization of Gap Junction Distribution in Dilated Atria of Patients With Chronic Atrial Fibrillation(CLINICAL INVESTIGATION)
• PJ-200 Aldosterone Modulated Gap Junction Remodeling through Mineralocorticoid Receptor(Arrhythmia, basic(05)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PE-010 Moderate Hypothermia Destabilized Spiral Waves without Widening Excitable Gap in Favor of Self-termination of Ventricular Tachycardia/Fibrillation(Arrhythmia, basic(03)(A),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese C
• Modulation of Spiral Wave Reentry by K^+ Channel Blockade(Mechanisms and Future Challenge)
• PE-330 Concentration-dependent Modification of Spiral-wave Reentry by Verapamil in a Perfused 2-dimensional Layer of Rabbit Ventricular Myocardium(Arrhythmia, basic-4 (A) PE55,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the
• OE-238 Mechanisms of Global and Regional Cooling-Assisted Defibrillation in a Bidomain Ventricular Model(Arrhythmia, basic-1 (A) OE40,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• Acute Amiodarone Suppresses Action Potential Alternans in the Two-dimensional Ventricular Myocardium of Rabbit Hearts(Arrhythmia, Basic 4 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Chronic Amiodarone Flattens Restitution of Action Potential Duration and Conduction Velocity through the Induction of Postrepolarization Refractoriness(Arrhythmia, Pharmacological Therapy 4 (A), The 69th Annual Scientific Meeting of the Japanese Circulati
• Familial Idiopathic Ventricular Fibrillation Characterized by Increased Dispersion of Ventricular Repolarization and Steep Restitution of the Action Potential Duration(Arrhythmia, Diagnosis/Pathophysiology/EPS 9 (A), The 69th Annual Scientific Meeting of
• Action Potential Dynamics of Spiral-type Reentry in 2-Dimensional Anisotropic Layer of Ventricular Muscle : Optical Mapping Analysis Using High-fidelity CMOS Camera(Arrhythmia, Basic 3 (A), The 69th Annual Scientific Meeting of the Japanese Circulation So
• PJ-035 Aldosterone is an Important Arrhythmogenic Substrate by Modulating the Gap Junction Channel Protein Connexin43(Arrhythmia, basic-5, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-034 T-type Ca^ Channel Modulates Gap Junction Remodeling through Renin-Angiotensin-Aldosterone System(Arrhythmia, basic-5, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• 1 Gap Junction Remodeling is an Important Arrhythmogenic Substrate during the Development of Heart Failure(Heart Failure and Arrhythmia, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PE-129 Aldosterone Modulates Gap Junction Remodeling in Cultured Rat Ventricular Myocytes(Arrhythmia, basic-3 (A) PE22,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• Gap Junction Remodeling is an Arrhythmogenic Substrate during the Development of Heart Failure in Cardiomyopathic Hamster(Arrhythmia, Basic 1 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-199 GDNF Acts as a More Potent Chemoattractant than NGF for Sympathetic Innervation in Cultured Ventricular Myocytes(Arrhythmia, basic(05)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• Long-term Effects of Amiodarone on T3-responsive Gene Expression Profiles in the Rat Heart, Liver and Pituitary(Arrhythmia, Basic 3 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Long-term Effects of Amiodarone and its Non-iodinated Analogue, Dronedarone, on the Transcription of Cardiac Sarcoplasmic Reticulum Ca^2+-ATPase Gene
• Right Ventricular Septal Pacing Preserves Long-Term Left Ventricular Function Via Minimizing Pacing-Induced Left Ventricular Dyssynchrony in Patients With Normal Baseline QRS Duration
• Action Potential Characteristics in the Sinus Venosa of Patients With and Without Atrial Flutter
• PJ-556 Intercellular Uncoupling Stabilizes Spiral-wave Reentry in Favor of its Persistence(PJ093,Ventricular Arrhythmia (Clinical/Diagnosis/Treatment) 2 (A),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• OE-428 β-Adrenergic Effects on the Dynamics of Spiral Wave Reentry in Langendorff-Perfused Rabbit Hearts(OE72,Arrhythmia, Mechanism (A),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• PJ-217 Limited Benefit of Atrial Resynchronization by the Bachmann's Bundle Pacing in the Prevention of Atrial Fibrillation(Arrhythmia, therapy(24)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-297 Bachmanns' Bundle Pacing has Advantage over Right Atrial Appendage Pacing of Avoiding Hemodynamic Perturbation Associated with Right-to-Left Atrial Contraction Delay(Arrhythmia, therapy-20, The 71st Annual Scientific Meeting of the Japanese Circula
• PE-281 Characteristics of Atrial Frequency Gradient in Patients with Paroxysmal Atrial Fibrillation not Eliminated by Pulmonary Vein Isolation Alone(Arrhythmia, therapy-12, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Internalization and Dephosphorylation of Connexin43 in Hypertrophied Right Ventricles of Rats With Pulmonary Hypertension
• PJ-624 Effects of Bepridil on Spatial and Temporal Dispersion of Repolarization in the Human Ventricle(Arrhythmia, therapy-19 (A) PJ105,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• PE-223 Action Potential Characteristics in the Posteromedial Right Atrium in Patients with Common Atrial Flutter(Arrhythmia, diagnosis/pathophysiology/EPS-10 (A) PE38,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese
• PE-020 Reduced Efficacy of Nifekalant in Decreasing Activation Frequency in the Left Atrium-pulmonary Vein Junction During Atrial Fibrillation(Arrhythmia, diagnosis/pathophysiology/EPS-6 (A) PE4,Poster Session (English),The 70th Anniversary Annual Scienti
• OE-279 Left-to-right Atrial Frequency Gradient Suggests the Presence of Rotors in the Left-atrium Pulmonary Vein Junction in the Human Atrial Fibrillation(Arrhythmia, diagnosis/pathophysiology/EPS-2 (A) OE47,Oral Presentation (English),The 70th Anniversar
• Reversal of Atrial Remodeling May Underlie Successful Cardioversion of Long-lasting Atrial Fibrillation with Bepridil(Arrhythmia, Pharmacological Therapy 4 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• FRS-020 Reconstitution of cardiac pacemaker sheets by the patterning of cell alignment using magnetic nanoparticles(New Insights into Basic Mechanism of Arrhythmia(A),Featured Research Session,The 72nd Annual Scientific Meeting of the Japanese Circulation
• MECHANISMS OF ATRIAL NATRIURETIC PEPTIDE (ANP) SECRETION BY RAT HEARTS PERFUSED IN VITRO : Ca^-dependent Signal Transduction for ANP Release by Mechanical Stretch
• -P16-BLOCK OF SODIUM CHANNELS BY AMIODARONE IN VENTRICULAR MYOCYTRES : Electrophysiology : FREE COMMUNICATIONS(III) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• -P15-SLOW INACTIVATION OF CARDIAC SODIUM CHANNELS : Electrophysiology : FREE COMMUNICATIONS(III) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• DIVERSE CHARACTERISTICS IN POTENTIAL WAVEFORM OF HIS-PURKINJE SYSTEM : Experimental and Simulation Studies
• EFFECTS OF KW-3049, A NEWLY DEVELOPED CALCIUM ANTAGONIST, ON RABBIT SINUS NODES AND GUINEA PIG VENTRICULAR MUSCLES
• -P247- EFFECTS OF ACTIVATION SEQUENCES AND ANISOTROPIC CELLULAR GEOMETRY ON THE REPOLARIZATION PHASE OF ACTION POTENTIALS OF DOG VENTRICULAR MUSCLES
• Endocardial Excitation and Conduction During Reperfusion Arrhythmias : SYMPOSIUM ON VENTRICULAR ARRHYTHMIA : BASIC AND CLINICAL STUDIES : 50th Annual Scientific Session of the Japanese Circulation Society
• -160-EFFECTS OF ISCHEMIA ON THE ENDOCARDIAL ACTIVATION SEQUENCE OF CANINE LEFT VENTRICLE
• Characteristics of Action Potentials in the Posteromedial Right Atrium : New Insights into the Mechanism of Conduction Block during Atrial Flutter(Arrhythmia, Diagnosis/Pathophysiology/EPS 10 (A), The 69th Annual Scientific Meeting of the Japanese Circula
• Bepridil Facilitates Early Termination of Spiral-Wave Reentry in Two-Dimensional Cardiac Muscle Through an Increase of Intercellular Electrical Coupling
• THE MECHANISM OF OVERDRIVE SUPPRESSION. : ACTIVATION OF ELECTROGENIC SODIUM PUMP FOLLOWRNG RAPID STIMULATION : IIIrd Auditorium
• IN VITRO STUDY ON THE CAUSE OF INTRAVENTRICULAR ABERRANT CONDUCTION. : COMPARISON OF THE FUNCTIONAL REFRACTORY PERIOD BETWEEN THE CANINE RIGHT AND LEFT BUNDLE BRANCH SYSTEMS : IVth Auditorium : PROCEEDINGS OF THE 40TH ANNUAL MEETING OF THE JAPANESE CIRCUL
• Pathophysiological Significance of T-type Ca^ Channels : Expression of T-type Ca^ Channels in Fetal and Diseased Heart
• Opposing Effects of Bepridil on Ventricular Repolarization in Humans : Inhomogeneous Prolongation of the Action Potential Duration vs Flattening of Its Restitution Kinetics
• PE-035 Association of Renal Artery Stenosis with Anemia and Heart-type Fatty Acid Binding Protein(PE006,Kidney/Renal Circulation/CKD 1 (H),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• DPE-017 Verapamil Remodels Paroxysmal Atrial Fibrillation via Acceleration of Fibrillation Frequency and Elimination of Pulmonary Vein-to-Left Atrial Frequency Gradient(DPE03,Atrial/Supraventricular Arrhythmia (Clinical/Treatment) (A),Digital Poster Sessi
• DPE-016 Possible Mechanism for Defibrillation of Long-Lasting Persistent Atrial Fibrillation with Bepridil(DPE03,Atrial/Supraventricular Arrhythmia (Clinical/Treatment) (A),Digital Poster Session (English),The 73rd Annual Scientific Meeting of The Japanes
• OJ-157 MK Gene Transfer Causes Amelioration of Cardiac Remodeling after Myocardial Infarction through Enhancements of Neovascularization and Cell Survival(OJ27,Coronary Circulation/Chronic Coronary Disease (Basic/Clinical) (IHD),Oral Presentation (Japanes
• OE-427 Ventricular Fibrillation in CHF is Characterized by the Existence of Multiple High-frequency Rotating Activities(OE72,Arrhythmia, Mechanism (A),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• OE-284 Bachmann's Bundle Pacing Ameliorates Efficacy of Cardiac Resynchronization Therapy via Achieving Atrial Mechanical Synchronization(OE48,CRT (M),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• Role of Ca^ Release from Sarcoplasmic Reticulum in Pacemaker Activity of the Sinoatrial Node
• Correlation between electrical activity and the size of rabbit sinoatrial node cells.
• PE-546 Midkine Plays and Angiogenetic Action through an Activation of Akt(Peripheral circulation/Vascular disease-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OE-269 Bepridil Reduces Dilatation-induced Vulnerability to Atrial Fibrillation in Rabbit Hearts through Prevention of Refractory Period Shortening and Heterogeneous Intraatrial Conduction(Arrhythmia, basic-2, The 71st Annual Scientific Meeting of the Jap
• FRS-014 Adenoviral Overexpression of Midkine Prevents the Left Ventricular Remodeling and Preserves the Cardiac Function after Myocardial Infarction(Cardiac Function "Ventricular Mechanics and Calcium Handling", The 71st Annual Scientific Meeting of the J
• PE-298 Feasibility of Undifferentiated ES Cell Engraftment to Diseased Hearts is Limited by Tumorigenesis and Apoptosis through Leukemia Inhibitory Factor (LIF)(Regeneration (angionenesis/myocardial regeneration)-5 (M) PE50,Poster Session (English),The 70
• FREQUENCY-DEPENDENT EFFECT OF COMBINED APPLICATION OF CLASS I ANTIARRHYTHMIC DRUGS ON INTRAVENTRICULAR CONDUCTION : A STUDY USING SIGNAL-AVERAGED ECG IN PATIENTS WITH IMPLANTED PACEMAKER
• De-differentiation is a mechanism of electrical-remodeling in diseased hearts
• Altered Action Potential Dynamics in Electrically Remodeled Canine Atria : Evidence for Altered Intracellular Ca^ Handling
• FRS-051 Role of Ca^-activated Signals and Ca^-handling Protein Phosphorylation Abnormalities in Electrical Storm(FRS11,New Insights into Basic Mechanisms of Arrhythmia (A),Featured Research Session (English),The 73rd Annual Scientific Meeting of T
• OE-312 Intracoronary application of midkine during reperfusion ameliorates ischemia/reperfusion injury in pig hearts(Myocardial ischemia/reperfusion, basic/clinical(01)(IHD),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Cir
• OE-083 Midkine Ameliorates Ischemia/Reperfusion Injury of Cardiac Muscle through a Reduction of Apoptotic Reaction(Myocardial Ischemia-Reperfusion, Basic and Clinical 1 (IHD) : OE10)(Oral Presentation (English))
• OJ-069 Effect of 1-week Administration of Calmodulin Antagonist W-7 in a New Experimental Model of Electrical Strom(Arrythmia, basic(02)(A),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• Adriamycin Causes Dual Inotropic Effects Through Complex Modulation of Myocardial Ca^ Handling
• OE-184 Exogenous Application of Midkine Prevents Ventricular Remodeling after Myocardial Infarction through Enhancement of Angiogenesis via PI3K/Akt Pathway.(Growth factor/Cytokine(01)(H),Oral Presentation(English),The 72nd Annual Scientific Meeting of th
• A New Device for Percutaneous Intramyocardial Injection of Bio-active Substances
• Down-regulation of Connexin 43 mRNA in Mouse Hearts after Myocardial Infarction
• Overexpression of Calpastatin by Adenovirus-Mediated Gene Transfer Prevents Reperfusion Injury in the Rat Heart
• Altered I_f Channel Gene Expression in Mouse Hearts after Myocardial Infarction
• Overexpression of Calpastatin Ameliorates Functional Recovery from Ischemic Injury in the Rat Heart
• OE-134 Gene profiling in a novel mouse model of acquired QT prolongation and Torsade de Pointes secondary to complete AV block(Arrhythmia, Basic 4 (A) : OE16)(Oral Presentation (English))
• Right Atrial Septal Pacing at the Bachmanns Bundle Ameliorates Mechanical Synchronization of Atria
• Restitution Kinetics of Ventricular Action Potential Duration in Patients with Short-Coupled Variant of Torsade de Pointes
• High Efficacy of Combined Use of Bepridil and Cibenzoline in Preventing AF Is the Result of Synergetic Prolongation of Refractoriness
• OE-146 Overexpression of Calmodurin Induces Transcriptional Downregulation of Kv4.2 and KChIP2 Channel Subunits in the Transgenic Mouse Heart.(Arrhythmia, basic(01)(A),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulati
• Protective effects of dimethyl amiloride, a Na^+/H^+ exchange inhibitor against ischemia-reperfusion injury of rabbit hearts : ^P-NMR study on ion dynamics and energy metabolism.
• PROTECTIVE ACTION OF DIMETHYLAMILIRIDE A POTENT INHIBITOR OF NA^+/H^+ EXCHANGE AGAINST ISCHEMIAREPERFUSION INJURY IN NEWBORN RABBIT HEARTS
• -0466-PROTECTIVE EFFECTS OF DEFEROXAMINE ON REPERFUSION INJURY OF NEONATAL RABBIT HEARTS FOLLOWING GLOBAL ISCHEMIA
• FRS-031 Midkine Prevents Cardiac Remodeling in Rabbit Congestive Heart Failure through Its Anti-apoptotic Effect(FRS7,Challenging Approaches to Heart Failure Treatment (M),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japan
• PJ-204 Subepicardial Ventricular Muscle in Tachycardia-induced Heart Failure Shows Prominent Rate-dependent Shortening of Action Potential Duration and Reduction of I_(Arrhythmia, basic(05)(A),Poster Session(Japanese),The 72nd Annual Scientific Meet
• OJ-070 Combined Effects of INa and ICa, Blockade on Spiral Wave Reentry in Perfused 2-dimensional Layer of Rabbit Ventricular Myocardium(Arrythmia, basic(02)(A),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Soc
• OJ-085 Prognostic Value of T-wave Polarity in Lead aVR in Patients with Heart Failure(Heart failure, clinical-05, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Altered expression of connexin43 contributes to the arrhythmogenic substrate during the development of heart failure in cardiomyopathic hamster
• Post-Overdrive Suppression of the Rabbit Sinus Node Pacemaker Cells : Symposium on Sinus Node Function and Its Abnormality
• PE-131 IKr Blocker Induces Interventricular APD Dispersion and Leads to Spiral Wave-type Polymorphic VT, But IKs Blocker Does Not in Rabbits(Arrhythmia, basic-3 (A) PE22,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japane
• Profiles of mRNA and Protein Expressions for Ion Channels and Connexins in the Pulmonary Vein of Rabbit Hearts (Arrhythmia, Basic 5 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Low-frequency Extracellular Potentials Recorded from the Sinoatrial Node
• Discrete Forms of Arrhythmogenic Ion-channel Remodeling Caused by Sustained Tachycardia and Bradycardia(Arrhythmia, Basic (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Effects of Long-term Oral Administration of Amiodarone on the Ventricular Repolarization of Rabbit Hearts

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