Modulation of Spiral Wave Reentry by K^+ Channel Blockade(Mechanisms and Future Challenge)

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概要

• 論文の詳細を見る

• It is well established that spiral wave reentry is the primary mechanism of ventricular tachyarrhythmias (ventricular fibrillation/tachycardia, VF/VT), but information is still limited concerning pharmacological modification of spiral waves by ion channel blockers. In this brief review, the antiarrhythmic and proarrhythmic actions of K+-channel blockade (/Kr and /Kl) are discussed in terms of spiral wave dynamics, primarily based on recent experimental findings in ventricular preparations perfused in vitro with the aid of high-resolution optical mapping, as well as their related theoretical studies using computer simulation.

• 社団法人日本循環器学会の論文
• 2007-06-20

著者

• Murato Y

  Division Of Cardiology Department Of Medicine And Clinical Science Yamaguchi University Graduate Sch

• Murata Yoshiharu

  Division Of Cardiology Department Of Medicine And Clinical Science Yamaguchi University Graduate Sch

• 児玉 逸雄

  名古屋大学環境医学研究所循環器部門

• Kodama Itsuo

  Department of Cardiovascular Research, Research Institute of Environmental Medicine, Nagoya Universi

• Kodama Itsuo

  静岡済生会総合病院 不整脈科

• YAMAZAKI Masatoshi

  Department of Medical Life Chemistry, Faculty of Pharmaceutical Sciences, Teikyo University

• HONJO Haruo

  Department of Humoral Regulation Division of Regulation of Organ Function Research Institute of Envi

• KAMIYA Kaichiro

  Department of Humoral Regulation Division of Regulation of Organ Function Research Institute of Envi

• Yamamoto Mitsuru

  名古屋大学環境医学研究所 循環器学

• Yamamoto M

  Department Of Cardiology Mitsubishi-nagoya Hospital

• Kodama Itsuo

  東京医科歯科大学生体材料工学研究所

• Yamazaki Masatoshi

  Division Of Cardiology Department Of Medicine And Clinical Science Yamaguchi University Graduate Sch

• Yamazaki Masatoshi

  名古屋大学環境医学研究所 循環器学

• Honjou Haruo

  名古屋大学 循環器内科学

• Honjou Haruo

  Department Of Humoral Regulation Research Institute Of Environmental Medicine Nagoya University

• Honjo Haruo

  名古屋大学環境医学研究所

• Honjo Haruo

  Department Of Cardiovascular Research Research Institute Of Environmental Medicine Nagoya University

• Kamiya K

  Division Of Cardiovascular Research Reseearch Institute Of Environmental Medicine Nagoya University

• Kamiya Kaichiro

  名古屋大学環境医学研究所 循環器学

• Kamiya K

  Nagoya Univ. Nagoya Jpn

• Kamiya Kaichiro

  Department Of Humoral Regulation The Research Institute Of Environmental Medicine Nagoya University

• Murata Yoshiharu

  Department Of Civil Engineering College Of Engineering Nihon University

• Murata Y

  Department Of Teratology And Genetics Research Institute Of Environmental Medicine Nagoya University

• Honjo Haruo

  Department Of Applied Physics Faculty Of Engineering

• Murata Yoshiharu

  Departments Of Genetics Research Institute Of Environmental Medicine Nagoya University

• Kamiya Kaichiro

  Department Of Cardiovascular Research Research Institute Of Environmental Medicine Nagoya University

• Kamiya Kaichiro

  Division Of Circulation And Respiration Research Institute Of Environmental Medicine Nagoya Universi

• Yamamoto Mariko

  名古屋大学環境医学研究所

• Murata Yoshiharu

  名古屋大学環境医学研究所 発生･遺伝学

• Yoshiga Masahiko

  The Department Of Cardiovascular Medicine Medical Bioregulation Yamaguchi University Graduate School

• Murata Yoshiharu

  Department Of Endocrinology And Metabolism Research Institute Of Environmental Medicine

• Yamazaki Masatoshi

  Division Of Cardiology Shizuoka Saiseikai General Hospital

• Yamazaki Masatoshi

  Department Of Circulation Research Institute Of Environmental Medicine Nagoya University

• Kodama Itsuo

  Department Of Cardiovascular Research R.i.e.m. Nagoya University

• Yamazaki Masatoshi

  Research Institute Of Environmental Medicine Nagoya University

• Murata Y

  Nagoya Univ. Nagoya‐shi

• Yamamoto Mitsuru

  名古屋大学環境医学研究所

• Yamazaki Masatoshi

  Division Of Cardiology Department Of Medicine And Clinical Science Yamaguchi University Graduate Sch

• Yamamoto Mitsuru

  Department Of Circulation Research Institute Of Environmental Medicine Nagoya Unoversity

• Yamamoto Masahiro

  Yokohama City Cerebrovascular Center Yokohama Japan

• 本荘 晴朗

  Department Of Cardiovascular Research Research Institute Of Environmental Medicine Nagoya University

• Yoshida Masaaki

  Division Of Cardiology Department Of Medicine And Clinical Science Yamaguchi University Graduate School Of Medicine

• Yamazaki Masatoshi

  Department of Cardiovascular Research, Research Institute of Environmental Medicine, Nagoya University

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