<原著>再発乳癌に対する外科的内分泌療法の検討

概要

論文の詳細を見る
The endocrine ablative surgery was undertaken in ten recurrent breast cancer patients at the 1st Department of Surgery, Kinki University Hospital during the past five-year period. Four premenopausal patients were treated with oophorectomy and six postmenopausal patients were undergone adrenalectomy, according to our program of the treatment for recurrent breast cancer. The assessment of response to the treatment was made by the diagnosis according to UICC criterion. In general, the breast cancer tissue is composed of heterogenous population, so-called mosaic pattern, of hormone dependent cells and independent cells ; namely, having estrogen receptor positive or negative cells. The estrogen receptor positive cells have highly sensitive response against the hormone treatment ; on the other hand, the negative cells have more sensitive response to anti-tumor agents. In this study, the authors speculated about that the combination of endocrine ablative surgery with chemotherapy proved more effective than endocrine ablative surgery or chemotherapy alone for the recurrent breast cancer. Therefore, the recurrent breast cancer patients might be improved in response rate and duration of remission.
近畿大学の論文
1981-09-25