Review of Regulation for the Fas-mediated Apoptotic Pathway in Silicosis Patients
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概要
- 論文の詳細を見る
The past several years, we have been investigating immunological aspects of silicosis focusing on Fas-mediated apoptosis. We found elevated serum level of soluble Fas (sFas) molecule, higher gene expression of sFas and decoy receptor 3 (DcR3) genes in peripheral blood mononuclear cells (PBMC) than healthy volunteers, and various alternatively spliced Fas transcripts in PBMC. The factor analysis using these results indicated that there were a small number of patients who developed immunological diseases without presenting with respiratory disorders. In addition, we discuss the mechanism involved in the development of autoimmune disorders found in silicosis patients.
- 川崎医科大学の論文
著者
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UEKI Ayako
Department of Hygiene, Kawasaki Medical School
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OTSUKI Takemi
Department of Hygiene, Kawasaki Medical School
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Ueki A
Department Of Rehabilitation Faculty Of Health Science And Technology Kawasaki University Of Medical
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Ueki Ayako
川崎医科大学 衛生学教室
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Ueki Ayako
川崎医療福祉大学
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Hyodoh Fuminori
Department of Hygiene, Kawasaki Medical School
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Otsuki T
Department Of Hygiene Kawasaki Medical School
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Otsuki Takemi
Department Of Hygiene Kawasaki Medical School
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Ueki A
Kawasaki University Of Medical Welfare
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Ueki Ayako
Department Of Hygiene
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Ueki Ayako
Department Of Anatomy Okayama University Medical School
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Hyodoh Fuminori
The First Department Of Nursing Kawasaki College Of Allied Health Professions
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Hyodoh Fuminori
Department Of Hygiene Kawasaki Medical School
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TAKATA Akiko
Department of Hygiene, Kawasaki Medical School
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TOMOKUNI Akiko
Department of Hygiene, Kawasaki Medical School
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Takata Akiko
Department Of Hygiene Kawasaki Medical School
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