Malaria Parasites Detected in Myanmar Thalassemia Patients
スポンサーリンク
概要
- 論文の詳細を見る
We examined the existence of malaria parasite carriers in 186 Myanmar transfusion dependent anemic patients with thalassemia mutations. Two malaria parasites, Plasmodium falciparum (Pf) and P. vivax (Pv), were detected by the PCR method using a multiplex primer set. Six patients were infected with Pf, and seven with Pv. The β-thalassemia (thal) genotypes and hemoglobinopathies were as follows; combination homozygote and/or heterozygote with Hb E and β^0-thal or β^+-thal, β^0-thal and , β^0-thal, orβ^0-thal andβ^+-thal. Among these patients, one had Hb H disease, one a'-thal-1 of the Southeast Asian genotype, and one a combination heterozygote of β^0-thal with α-thal-2. Although they were Pf or Pv carriers, they manifested no clinical symptoms due to malaria infection. Therefore, it might be suggested that thal patients have resistance to malaria.
- 川崎医科大学の論文
著者
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Hodohara Keiko
Department Of Medicine Shiga University Of Medical Science
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HARANO Teruo
Department of Biochemistry, Kawasaki Medical School
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Aung Myint
Department Of Biochemistry Kawasaki Medical School
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HARANO Keiko
Department of Clinical Nutrition, Faculty of Medical Professions, Kawasaki University of Medical Wel
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Hodohara Keiko
Department Of Hematology Of Shiga University Of Medical Science
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Harano K
Department Of Clinical Nutrition Faculty Of Medical Professions Kawasaki University Of Medical Welfa
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Harano Keiko
Department Of Biochemistry Kawasaki Medical School
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Harano T
Department Of Biochemistry Kawasaki Medical School
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Harano Teruo
Department Of Biochemistry Kawasaki Medical School
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HARANO Keiko
Department of Biochemistry and Department of Clinical Pathology, Kawasaki Medical School
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HARANO Teruo
Department of Biochemistry and Department of Clinical Pathology, Kawasaki Medical School
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