MR Characterization of Focal Nodular Hyperplasia : Gadoxetic Acid versus Superparamagnetic Iron Oxide Imaging
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概要
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Purpose: We evaluated the diagnostic efficacy of gadoxetic acid- and superparamagnetic iron oxide (SPIO)-enhanced magnetic resonance (MR) imaging for focal nodular hyperplasia (FNH). Materials and Methods: We retrospectively evaluated 11 patients with 11 FNHs. Both gadoxetic acid- and SPIO-enhanced MR imaging were performed. A 3-dimensional (3D) volumetric interpolated breath-hold examination was used with the gadoxetic acid dynamic study. SPIO-enhanced MR imaging included T2- and T2*-weighted images. We quantitatively and qualitatively compared lesion-specific enhancement of both contrast media. Results: The mean signal-to-noise (S/N) ratio of the FNH lesions differed significantly on pre- and postenhanced imaging of each contrast medium (P<0.05); mean contrast-to-noise (C/N) ratio did not (P>0.05). All observers described all lesions as hyperintense in the arterial phase on gadoxetic acid-enhanced MR imaging and observed the presence of central scar, fibrous septa, and rim most clearly in gadoxetic acid-enhanced hepatobiliary phase images. Conclusion: Gadoxetic acid-enhanced MR imaging was more useful than SPIO-enhanced MR imaging in characterizing FNH.
- 2012-09-01
著者
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Tokuuye Koichi
Department Of Radiation Oncology Graduate School Of Comprehensive Human Sciences University Of Tsuku
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SUGIMOTO Katsutoshi
Department of Gastroenterology & Hepatology, Tokyo Medical University
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Moriyasu Fuminori
Department Of Gastroenterology & Hepatology Tokyo Medical University
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Park Jinho
Department Of Radiology Tokyo Medical University
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Saito Kazuhiro
Department Of Chemistry Faculty Of Science Yamagata University
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SAGUCHI Toru
Department of Radiology, Tokyo Medical University
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YOSHIMURA Nobutaka
Department of Radiology, Tokyo Medical University
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AKATA Soichi
Department of Radiology, Tokyo Medical University
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MORIYASU Fuminori
Department of Gastroenterology and Hepatology, Tokyo Medical University
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Saito Kazuhiro
Department of Radiology, Tokyo Medical University
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SUGIMOTO Katsutoshi
Department of Gastroenterology and Hepatology, Tokyo Medical University
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