Dynamic MR Cholangiography after Fatty Meal Loading : Cystic Contractility and Dynamic Evaluation of Biliary Stasis
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概要
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Purpose: Dynamic MR cholangiography was conducted on patients with cholelithiasis or choledocholithiasis who had consumed a fatty test meal (Molyork) and the cystic contractility and dynamics of biliary stasis was evaluated.Subjects and Method: The subjects were 25 with intracystic cholelithiasis, 10 with choledocholithiasis and 10 normal controls. For an imaging sequence, the rapid acquisition with relaxation enhancement (RARE) method was employed and imaging was conducted for 40 min (every 30 s following Molyork administration) without breath-holding. The gallbladder contraction ratio was computed and the contractile ratio for the common bile duct was calculated. To determine the bile flow to the duodenum, the high-intensity signal, indicating the flow from the lower common bile duct, and perfusion of the duodenum were observed in dynamic mode on the monitor with the naked eye and interpreted as positive bile flow. The frequency of this flow was visually monitored.Results: The gallbladder contractile ratio was significantly reduced in patients with cholelithiasis or choledocholithiasis compared with the controls. In a comparison with the normal controls, no sequential changes were noted in the mean contractile ratio of the common bile duct of the patients with cholelithiasis or choledocholithiasis. The mean frequency of bile flow observed for each 40 min period was 13±2.4, 6±2.2, and 4±1.3 times for the controls, those with intracystic cholelithiasis, and those with choledocholithiasis, respectively. Compared with the controls, the latter two patient groups showed evident reductions in the frequency of bile flow to the duodenum (p<0.001).Conclusion: Dynamic MRC combined with Molyork loading makes it possible to compute cystic contractile ratios and perform a dynamic examination of bile flow under non-invasive, near-physiological conditions.
- 日本磁気共鳴医学会の論文
- 2002-07-01
著者
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Mizokami Yuji
Department Of Anatomic Pathology Tohoku Kosai Hospital
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Masuda T
Division Of Gastroenterological Surgery Tohoku University Graduate School Of Medicine
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Satani Kenichiro
Department Of Radiology Tokyo Medical University
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Matsuoka Takeshi
College Of Medical Sciences Tohoku University
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Murakami Takashi
東北大学 医学部産婦人科学周産期医学
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MATSUOKA Takeshi
Department of Internal Medicine 5, Tokyo Medical Unvierstiy
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ABE Kimihiko
Department of Radiology, Tokyo Medical College
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Abe Kimihiko
Department Of Radiology Tokyo Medical University
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Matsuoka Takeshi
Department Of Applied Physics Faculty Of Engineering Hokkaido University:(present Address)communicat
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SAITO Kazuhiro
Department of Radiology, Tokyo Medial University Kasumigaura Hospital
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KOTAKE Fumio
Department of Radiology, Tokyo Medial University Kasumigaura Hospital
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OMATA Takayuki
Department of Internal Medicine 5, Tokyo Medical University Kasumigaura Hospital
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Kotake Fumio
Department Of Radiology Tokyo Medical University Kasumigaura Hospital
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Omata Takayuki
Department Of Internal Medicine 5 Tokyo Medical University Kasumigaura Hospital
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Matsuoka Takeshi
Department Of Internal Medicine 5 Tokyo Medical University Kasumigaura Hospital
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Abe Kimihiko
Department Of Clinical Radiology Graduate School Of Medical Sciences Kyushu University
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Saito Kazuhiro
Department Of Radiology Tokyo Medical University
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Saito Kazuhiro
Department Of Chemistry Faculty Of Science Yamagata University
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