Association study of genetic polymorphism in ABCC4 with cyclophosphamide-induced adverse drug reactions in breast cancer patients

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概要

• 論文の詳細を見る
• Nature Publishing Groupの論文
• 2009-10-01

著者

• Mushiroda Taisei

  理化学研究所ゲノム医科学研究センター 循環器疾患研究チーム

• Mushiroda Taisei

  Laboratory For Pharmacogenetics Snp Research Center The Institute Of Physical And Chemical Research

• Mushiroda Taisei

  Laboratory For Pharmacogenetics Riken Snp Research Center

• Nagane Y

  Sanai Hospital Iwate Jpn

• Nagane Yutaka

  東京大学医科学研究所ヒトゲノム解析センター

• Nagane Yutaka

  Department Of Urology Sanai Hospital

• Kiyotani Kazuma

  Laboratory For Pharmacogenetics Snp Research Center The Institute Of Physical And Chemical Research

• Nakamura Y

  Center For Genomic Medicine Riken

• Nakata Yoshio

  理化学研究所ゲノム医科学研究センター 内分泌･代謝疾患チーム

• Zembutsu Hitoshi

  Laboratory Of Molecular Medicine Human Genome Center Institute Of Medical Science The University Of

• Zembutsu Hitoshi

  First Department Of Surgery Sapporo Medical University School Of Medicine

• Nakamura Yusuke

  Laboratory Of Molecular Medicine Human Genome Center Institute Of Medical Science University Of Toky

• Nakamura Yusuke

  Laboratory For Genotyping Riken Snp Research Center C/o Riken Yokohama Institute

• Daigo Yataro

  Laboratory Of Genome Technology Human Genome Center Institute Of Medical Science The University Of Tokyo

• Nakamura Yusuke

  Laboratory For Pharmacogenetics Snp Research Center The Institute Of Physical And Chemical Research (riken)

• Low Siew-kee

  Laboratory Of Molecular Medicine Human Genome Center Institute Of Medical Science The University Of Tokyo

• Kiyotani Kazuma

  Laboratory For Pharmacogenetics Riken Center For Genomic Medicine

• Mushiroda Taisei

  Laboratory For Phamacogenetics Riken Center For Genomic Medicine

関連論文

• OE-294 A Functional Variation in a Gene Encoding One of Galectin-2 Binding Proteins Confers Risk of Myocardial Infarction in Asian Populations(OE50,Coronary Circulation/Chronic Coronary Disease (Basic/Clinical) (IHD),Oral Presentation (English),The 73rd A
• OE-009 Identification of a Locus on Chromosome 5p that Confers Risk of Coronary Artery Disease by Genome Wide Association Study(OE02,ACS/AMI (Basic) (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• FRS-004 Large Scale SNPs Association Study to Identify Genes Confer Risk of Myocardial Infarction(FRS1,New Molecules for Cardiovascular Regulation (M),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Socie
• Overrepresentation of the EBAG9 Gene at 8q23 Associated with Early-Stage Breast Cancers
• 4 Effects of EPA on coronary artery disease in patients with gluco-metabolism derangement : JELIS subgroup analysis(Late Breaking Clinical Trials II,Special Program,The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• 4 Effects of EPA on coronary artery disease in hypercholesterolemic patients with multiple risk factors : Sub-analysis of primary prevention cases from JELIS(Late Breaking Clinical Trials I,Special Program,The 72nd Annual Scientific Meeting of the Japanes
• 3 Effectiveness of eicosapentaenoic acid in preventing coronary artery disease : Secondary prevention strata from JELIS.(Late Breaking Clinical Trials I,Special Program,The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• Central Obesity and Health-related Factors among Middle-aged Men : a Comparison among Native Japanese and Japanese-Brazilians Residing in Brazil and Japan
• New correction algorithms for multiple comparisons in case-control multilocus association studies based on haplotypes and diplotype configurations
• A functional SNP in the NKX2.5-binding site of ITPR3 promoter is associated with susceptibility to systemic lupus erythematosus in Japanese population
• Identification of a significant association of a single nucleotide polymorphism in TNXB with systemic lupus erythematosus in a Japanese population
• High-resolution SNP and haplotype maps of the human gamma-glutamyl carboxylase gene (GGCX) and association study between polymorphisms in GGCX and the warfarin maintenance dose requirement of the Japanese population
• A functional SNP in ITIH3 is associated with susceptibility to myocardial infarction
• Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial infarction
• Association of VKORC1 and CYP2C9 polymorphisms with warfarin dose requirements in Japanese patients
• Japanese single nucleotide polymorphism database for 267 possible drug-related genes
• PJ-438 Identification of Proteins that Bind Galectin-2, Encoded by a Gene Associated with Myocardial Infarction Using Tandem Affinity Purification Method(Acute myocardial infarction, basic-4 (IHD) PJ74,Poster Session (Japanese),The 70th Anniversary Annual
• Association of a single-nucleotide polymorphism in the immunoglobulin μ-binding protein 2 gene with immunoglobulin A nephropathy
• Association of single-nucleotide polymorphisms in the polymeric immunoglobulin receptor gene with immunoglobulin A nephropathy (IgAN) in Japanese patients
• Single-nucleotide polymorphisms in the class II region of the major histocompatibility complex in Japanese patients with immunoglobulin A nephropathy
• A high-throughput SNP typing system for genome-wide association studies
• PJ-152 A functional SNP in the Proteasome Subunit Alpha Type 6 Gene confers Risk of Myocardial Infarction in Japanese Population(Acute myocardial infarction, basic-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-212 Identification of a Novel non-coding RNA, MIAT, that Confers Risk of Myocardial Infarction(Genetics/Genetically engineered models/Gene therapy-2(H/M), The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• OJ-340 Large-Scale Genetic Association Study of 30 Inflammation-Related Genes for Myocardial Infarction Using Tag SNPs from HapMap Data(Genetics/Genetically engineered models/Gene therapy-1 (M) OJ57,Oral Presentation (Japanese),The 70th Anniversary Annual
• Fine-scale SNP map of an 11-kb genomic region at 22q13.1 containing the galectin-1 gene
• PJ-363 Functional Impacts of Selectin Haplotypes on Leukocyte-endothelial Interaction(Molecular Biology, Vascular 2 (H) : PJ61)(Poster Session (Japanese))
• High-resolution SNP map of ASPN, a susceptibility gene for osteoarthritis
• Identification of C2orf18, termed ANT2BP (ANT2-binding protein), as one of the key molecules involved in pancreatic carcinogenesis
• A Mutation in the Flavin-containing Monooxygenase 3 Gene and its Effects on Catalytic Activity for N-oxidation of Trimethylamine In Vitro
• Genetic variations in the gene encoding TFAP2B are associated with type 2 diabetes mellitus
• Distinct pattern of gene expression in pyothorax-associated lymphoma (PAL), a lymphoma developing in long-standing inflammation
• 川崎病不全型の冠動脈障害出現頻度
• A genomewide linkage analysis of Kawasaki disease : evidence for linkage to chromosome 12
• Combinational effect of genes for the renin-angiotensin system in conferring susceptibility to diabetic nephropathy
• Critical roles of T-LAK cell-originated protein kinase in cytokinesis
• Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis
• Association analysis of SLC22A4, SLC22A5 and DLG5 in Japanese patients with Crohn disease
• Impact of CYP2D6^*10 on recurrence-free survival in breast cancer patients receiving adjuvant tamoxifen therapy
• Association of genetic polymorphisms in SLCO1B3 and ABCC2 with docetaxel-induced leukopenia
• Physical activity and intra-abdominal fat reduction : effects of age, obesity phenotype and vigorous physical activity
• 川崎病の6つの主要症状と冠動脈後遺症
• Monthly Observation of the Number of Patients with Kawasaki Disease and its Incidence Rates in Japan : Chronological and Geographical Observation from Nationwide Surveys
• Epidemiologic Features of Kawasaki Disease in Japan : Results from the Nationwide Survey in 2005-2006
• Radioimmunotherapy of solid tumors targeting a cell-surface protein, FZD10 : therapeutic efficacy largely depends on radiosensitivity
• Radioimmunotherapy of human synovial sarcoma using a monoclonal antibody against FZD10
• Overexpression of the Wilms' tumor gene WT1 in primary astrocytic tumors
• Stanniocalcin 2 overexpression in castration-resistant prostate cancer and aggressive prostate cancer
• Measurement of spleen volume is useful for distinguishing between simple steatosis and early-stage non-alcoholic steatohepatitis
• Inference from the relationships between linkage disequilibrium and allele frequency distributions of 240 candidate SNPs in 109 drug-related genes in four Asian populations
• Identification of 20 novel SNPs in the guanine nucleotide binding protein alpha 12 gene locus
• Catalog of 300 SNPs in 23 genes encoding G-protein coupled receptors
• Inverse correlation of the up-regulation of FZD10 expression and the activation of β-catenin in synchronous colorectal tumors
• Potential involvement of p53 in ischemia/reperfusion-induced osteonecrosis
• Automated SNPs typing system based on the Invader assay
• Orphan receptor tyrosine kinase ROR2 as a potential therapeutic target for osteosarcoma
• Activation of an estrogen/estrogen receptor signaling by BIG3 through its inhibitory effect on nuclear transport of PHB2/REA in breast cancer
• Involvement of G-patch domain containing 2 overexpression in breast carcinogenesis
• Overexpression of the potential kinase serine/threonine/tyrosine kinase 1 (STYK 1) in castration-resistant prostate cancer
• Aotake : A modified stepping exercise as a useful means of improving lower-extremity functional fitness in older adults
• Serum tumor antigen REG4 as a diagnostic biomarker in pancreatic ductal adenocarcinoma
• Identification of sequence polymorphisms in CALM2 and analysis of association with hip osteoarthritis in a Japanese population
• Epidemiologic Features of Kawasaki Disease in Japan : Results of the 2007-2008 Nationwide Survey
• 5αDH-DOC (5α-dihydro-deoxycorticosterone) activates androgen receptor in castration-resistant prostate cancer
• Association between single nucleotide polymorphisms within genes encoding sirtuin families and diabetic nephropathy in Japanese subjects with type 2 diabetes
• 川崎病巨大冠動脈瘤の症例対照研究 : 第19回川崎病全国調査
• DISCRIMINATION BETWEEN SCLEROSING CHOLANGITIS-ASSOCIATED AUTOIMMUNE PANCREATITIS AND PRIMARY SCLEROSING CHOLANGITIS, CANCER USING INTRADUCTAL ULTRASONOGRAPHY
• Effects of regular exercise combined with ingestion of vespa amino acid mixture on aerobic fitness and cardiovascular disease risk factors in sedentary older women : A preliminary study
• A simple clinical scoring system using ferritin, fasting insulin, and type IV collagen 7S for predicting steatohepatitis in nonalcoholic fatty liver disease
• Complications of the treatment of endoscopic biliary strictures developing after liver transplantation
• Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility
• 川崎病の既往を有する親の疫学特性
• Expression of Toll-like Receptors in the Pancreas of Recent-onset Fulminant Type 1 Diabetes
• Association analysis of the NOD2 gene with susceptibility to graft-versus-host disease in a Japanese population
• Expression of chemokines, CXC chemokine ligand 10 (CXCL10) and CXCR3 in the inflamed islets of patients with recent-onset autoimmune type 1 diabetes
• Kawasaki Disease in Mongolia : Results From 2 Nationwide Retrospective Surveys, 1996-2008
• Relationship between the Cumulative Incidence of Kawasaki Disease and the Prevalence of Electrocardiographic Abnormalities in Birth-Year Cohorts
• Genome-wide association studies of tuberculosis in Asians identify distinct at-risk locus for young tuberculosis
• Genetic differences in the two main groups of the Japanese population based on autosomal SNPs and haplotypes
• Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography
• A genome-wide association study identifies novel susceptibility genetic variation for thyrotoxic hypokalemic periodic paralysis
• SNPs on chromosome 5p15.3 associated with myocardial infarction in Japanese population
• Genetic variations in the CYP17A1 and NT5C2 genes are associated with a reduction in visceral and subcutaneous fat areas in Japanese women
• Computed tomography analysis of the association between the SH2B1 rs7498665 single-nucleotide polymorphism and visceral fat area
• Association of variations in the FTO, SCG3 and MTMR9 genes with metabolic syndrome in a Japanese population
• Identification of independent risk loci for Graves' disease within the MHC in the Japanese population
• Common variants on 14q32 and 13q12 are associated with DLBCL susceptibility
• Impact of LIMK1, MMP2 and TNF-α variations for intracranial aneurysm in Japanese population
• A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population
• Polymorphisms in NRXN3, TFAP2B, MSRA, LYPLAL1, FTO and MC4R and their effect on visceral fat area in the Japanese population
• Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population
• Screening of 336 single-nucleotide polymorphisms in 85 obesity-related genes revealed McKusick-Kaufman syndrome gene variants are associated with metabolic syndrome
• Genome-wide association studies of tuberculosis in Asians identify distinct at-risk locus for young tuberculosis
• Establishment of a standardized system to perform population structure analyses with limited sample size or with different sets of SNP genotypes
• Making a haplotype catalog with estimated frequencies based on SNP homozygotes
• Association study of the polymorphisms on chromosome 12p13 with atherothrombotic stroke in the Japanese population
• Single nucleotide polymorphism in ABCG2 is associated with irinotecan-induced severe myelosuppression
• Association study of genetic polymorphism in ABCC4 with cyclophosphamide-induced adverse drug reactions in breast cancer patients
• A genome-wide association study identifies ITGA9 conferring risk of nasopharyngeal carcinoma
• Preventive Effects of Eicosapentaenoic Acid on Coronary Artery Disease in Patients With Peripheral Artery Disease : Subanalysis of the JELIS Trial
• Case-control association study of 59 candidate genes reveals the DRD2 SNP rs6277 (C957T) as the only susceptibility factor for schizophrenia in the Bulgarian population

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