Novel mechanism of angiotensin II-induced cardiac injury in hypertensive rats : the critical role of ASK1 and VEGF
スポンサーリンク
概要
- 論文の詳細を見る
- 2012-02-01
著者
-
Kim Mitsuyama
Department Of Pharmacology And Molecular Therapeutics Kumamoto University Graduate School Of Medical
-
Kamide Kei
Department Of Geriatric Medicine Ehime University Graduate School Of Medicine
-
Nako Hisato
Department Of Pharmacology And Molecular Therapeutics Kumamoto University Graduate School Of Medical
-
Yasuda Osamu
Department Of Geriatric Medicine And Nephrology Osaka University Graduate School Of Medicine
-
Dong Yi
Department Of Pharmacology And Molecular Therapeutics Kumamoto University Graduate School Of Medical
-
Kataoka Keiichiro
Department Of Pharmacology And Molecular Therapeutics Kumamoto University Graduate School Of Medical
-
Koibuchi Nobutaka
Department Of Advanced Clinical Science And Therapeutics Graduate School Of Medicine The University
-
Ogawa Hisao
Department Cardiovascular Medicine Kumamoto University:division Of Intensive Care Unit Kumamoto Univ
-
Toyama Kensuke
Department Of Cardiology Fukuoka Tokushukai Medical Center
-
Nako Hisato
Department Of Cardiovascular Medicine Graduate School Of Medical Sciences Kumamoto University
-
Ichijo Hidenori
Laboratory Of Cell Signaling Graduate School Of Pharmaceutical Sciences The University Of Tokyo
-
Kitahara Koichi
Department Of Cardiology Sakakibara Heart Institute
-
Yamamoto Eiichiro
Department Of Pharmacology And Molecular Therapeutics Kumamoto University Graduate School Of Medical
-
Yamamoto Eiichiro
Department Of Biochemistry Cancer Research Institute
-
Kangawa Kenji
Department Of Medicine And Geriatrics Osaka University Medical School:sakurabashi Watanabe Hospital
-
Kim-mitsuyama Shokei
Department Of Cardiovascular Medicine Wakayama Medical University
-
Kataoka Keiichiro
Department Of Cardiovascular Medicine Graduate School Of Medicine Kumamoto University
-
Kim Mitsuyama
Department Of Pharmacology And Molecular Therapeutics Kumamoto University Graduate School Of Medical Sciences
-
DONG Yi-Fei
Department of Pharmacology and Molecular Therapeutics, Kumamoto University Graduate School of Medical Sciences
-
Toyama Kensuke
Department Of Pharmacology And Molecular Therapeutics Kumamoto University Graduate School Of Medical Sciences
-
Yasuda Osamu
Department Of Cardiovascular Clinical And Translational Research Kumamoto University Hospital
-
Ichijo Hidenori
Laboratory Of Cell Signaling Tokyo University Graduate School Of Pharmaceutical Sciences
-
Koibuchi Nobutaka
Department Of Pharmacology And Molecular Therapeutics Kumamoto University Graduate School Of Medical Sciences
-
KIM MITSUYAMA
Department of Pharmacology and Molecular Therapeutics, Kumamoto University Graduate School of Medical Sciences
-
Ogawa Hisao
Department of Cardiovascular Medicine, Kumamoto University Graduate School of Medical Sciences
-
Kataoka Keiichiro
Department of Pharmacology and Molecular Therapeutics, Kumamoto University Graduate School of Medical Sciences
関連論文
- One-year effectiveness and safety of open-label losartan/hydrochlorothiazide combination therapy in Japanese patients with hypertension uncontrolled with ARBs or ACE inhibitors
- Rationale, design and patient baseline characteristics of OlmeSartan and calcium antagonists randomized (OSCAR) study : a study comparing the incidence of cardiovascular events between high-dose angiotensin II receptor blocker (ARB) monotherapy and combin
- PE-533 The Combination of Selective Aldosterone Blocker and CCB Exerts Additive Protective Effects against Salt-sensitive Hypertension-induced Cardiovascular Injury(PE089,Cardiomyopathy/Hypertrophy (Basic) (M),Poster Session (English),The 73rd Annual Scie
- Association of gene polymorphism of the fat-mass and obesity-associated gene with insulin resistance in Japanese
- Fas promoter region gene polymorphism is associated with an increased risk for myocardial infarction
- OJ-108 Inhibition of Apop Gene Expression Prevents Death of Cells in Culture Following Hypoxia/Reoxygenation(Cell death, apoptosis/necrosis(M),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Hypoadiponectinemia is Associated With Impaired Glucose Tolerance and Coronary Artery Disease in Non-Diabetic Men
- Smoking cessation is associated with increased plasma adiponectin levels in men
- PE-372 Smoking Cessation is Associated with Increased Plasma Levels of Adiponectin in Men with Stable Effort Angina(Smoking, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Diabetes Mellitus Is a Major Negative Determinant of Coronary Plaque Regression During Statin Therapy in Patients With Acute Coronary Syndrome : Serial Intravascular Ultrasound Observations From the Japan Assessment of Pitavastatin and Atorvastatin in Acu
- Guidelines for Diagnosis and Treatment of Patients With Vasospastic Angina (Coronary Spastic Angina) (JCS 2008) : Digest Version
- Waveform of Ophthalmic Artery Doppler Flow Predicts the Severity of Systemic Atherosclerosis
- Standard-Dose Statin Therapy Provides Incremental Clinical Benefits in Normocholesterolemic Diabetic Patients
- PE-012 Admission White Blood Cell Count and Plasma Glucose : Simple and Useful Combination for Predicting In-hospital Outcome after Acute Myocardial Infarction(Acute myocardial infarction, clinical (diagnosis/treatment)-5 (IHD) PE2,Poster Session (English
- Effects of Glucose Abnormalities on In-hospital Outcome After Coronary Intervention for Acute Myocardial Infarction (Acute Myocardial Infarction, Clinical (Pathophysiology) 5 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Fas Ligand mRNA Levels of Circulating Leukocytes Reflect Endothelial Dysfunction in Hyperlipidemic but Not in Non-Hyperlipidemic Patients
- PJ-032 Fas Ligand Expression Levels in Mononuclear Cells May Indicate the Degree of Improvement of Endothelial Function by Statin(Endothelium-5 (H) PJ6,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation So
- Fas Ligand mRNA Levels of Peripheral Blood Mononuclear Cells may be a Novel Clinical Marker in Patients with Hyperlipidemia (Atherosclerosis, Clinical 10 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-767 Combined Prognostic Utility of White Blood Cell Count, Plasma Glucose Level, and Glomerular Filtration Rate in Acute Myocardial Infarction(PJ129,Myocardial Ischemia-reperfusion (Basic, Clinical) (IHD),Poster Session (Japanese),The 73rd Annual Scien
- Impact of Body Mass Index on In-Hospital Outcomes After Percutaneous Coronary Intervention for ST Segment Elevation Acute Myocardial Infarction
- Increased heart rate variability during sleep is a predictor for future cardiovascular events in patients with type 2 diabetes
- 3 Effects of Anti-postprandial Hyperglycemia Drugs on the Coronary Atherosclerosis in Early Stage Diabetic Patients with Coronary Artery Disease : A Study of the DIAbetes and Diffuse Coronary NArrowing (DIANA)(Late Breaking Clinical Trials I,The 73rd Annu
- Weekend Onset of Acute Myocardial Infarction Does Not Have a Negative Impact on Outcome in Japan
- PJ-178 Gender Differences in Outcomes after Primary Coronary Intervention for Acute Myocardial Infarction(Acute myocardial infarction, clinical (pathophysiology)-5, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Long-Term Nitrate Therapy After Acute Myocardial Infarction Does not Improve or Aggravate Prognosis
- Sex Differences in Early Mortality of Patients Undergoing Primary Stenting for Acute Myocardial Infarction
- Beneficial Effect of Preinfarction Angina on In-Hospital Outcome is Preserved in Elderly Patients Undergoing Coronary Intervention for Anterior Acute Myocardial Infarction
- Effects of Glucose Abnormalities on In-Hospital Outcome After Coronary Intervention for Acute Myocardial Infarction
- Usefulness of Hydrophilic vs Lipophilic Statins After Acute Myocardial Infarction : Subanalysis of MUSASHI-AMI
- Exogenous Ouabain Is Accumulated in the Adrenals and Mimics the Kinetics of Endogenous Digitalis-like Factor in Rats
- Comparison of effects of estriol on bone mineral density of vertebrae between elderly and postmenopausal women
- PE-347 Fas may have apoptosis-unrelated biological functions in the vasculature.(Molecular Biology, Vascular 3 (H) : PE59)(Poster Session (English))
- Relationship between Severity of Coronary Artery Stenosis and of Calcificaton and CKD : Comparisons of CT Coronary Angiography with eGFR in Patients with Cardiovascular Disease
- PE-540 ASK2 Deficient Mice Have Elevated Blood Pressure with Cardiac Hypertrophy and Remodeling Mediated by Angiotensin II(PE091,Molecular Biology (M),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-135 ASK1 and ASK2 are Differentially Involved in Salt Induced Blood Presssure Elevation and Cardiac Injury(OJ23,Hypertension, Basic (H),Oral Presentation (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- Combination therapy of angiotensin receptor blocker with statin or thiazolidinediones as promising therapeutic strategy for metabolic syndrome and atherosclerosis
- Tissue Inhibitor of Metalloproteinase-3 Deficiency Inhibits Blood Pressure Elevation and Myocardial Microvascular Remodeling Induced by Chronic Administration of N^ω-Nitro-L-Arginine Methyl Ester in Mice
- Tissue Inhibitor of Metalloproteinase-3 Plays Important Roles in the Kidney Following Unilateral Ureteral Obstruction
- PJ-378 Forkhead transcriptional factor induces apoptosis in vascular smooth muscle cells, and reduces neointima formation after balloon injury in rats(Apoptosis/Necrosis/Regeneration 1 (M) : PJ63)(Poster Session (Japanese))
- PJ-634 Apoptois Signal-Regulating Kinase 1 (ASK1) Plays a Pivotal Role in Aldosterone-induced Cardiac Inflammation, Fibrosis and Vascular Endothelial Dysfunction(PJ107,Cardiomyopathy/Hypertrophy (Basic, Clinical) (M),Poster Session (Japanese),The 73rd Ann
- PE-019 Angiotensin II-Induced Reactive Oxygen Species via eNOS Uncoupling, Rather than NADPH Oxidase, is Involved in Hypertensive Cardiovascular and Kidney Disease(PE004,Hypertension, Basic (H),Poster Session (English),The 73rd Annual Scientific Meeting o
- Beneficial Effect of Candesartan on Rat Diastolic Heart Failure
- Excess Aldosterone under Normal Salt Diet Induces Cardiac Hypertrophy and Infiltration via Oxidative Stress
- Additive Beneficial Effects of the Combination of a Calcium Channel Blocker and an Angiotensin Blocker on a Hypertensive Rat-Heart Failure Model
- Different changes of bone mineral density and nutritional status after hospitalization between vascular dementia and Alzheimer's disease in elderly female patients
- RELATIONSHIP BETWEEN CORONARY ARTERY STENOSIS AND RENAL DYSFUNCTION:COMPARISONS OF MULTIDETECTOR-ROW CT CORONARY ANGIOGRAMS WITH ESTIMATED GLOMERULAR FILTRATION RATES
- The effect of edaravone on plasma monocyte chemoattractant protein-1 levels in patients with acute myocardial infarction
- Quadriceps sarcopenia and visceral obesity are risk factors for postural instability in the middle-aged to elderly population
- Associations between short one-leg standing time and speed of sound of calcaneal bone in a general population : The Shimanami Health Promoting Program (J-SHIPP) study
- Nifedipine Upregulates Manganese Superoxide Dismutase Expression in Vascular Smooth Muscle Cells via Endothelial Cell-Dependent Pathways
- PJ-034 Apoptosis Signal-regulating Kinase 1 (ASK1) May Mediate Endothelial Cell Senescence and Plasminogen Activator Inhibitor-1 (PAI-1) Expression in Diabetic Mice(Endothelium-5 (H) PJ6,Poster Session (Japanese),The 70th Anniversary Annual Scientific Mee
- Tissue Inhibitor of Metalloproteinase-3-deficiency Prevents L-NAME Induced Perivascular Fibrosis(Hypertension, Basic 2 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Apoptosis Signal-regulating Kinase 1 (ASK1) May Mediate Endothelial Cell Senescence and Thrombogenesis in Diabetic Mice(Endothelium/NO 1 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-175 Tissue Inhibitor of Metalloproteinase-3-deficiency Prevents Hypertension Induced by Nitric Oxide Synthase Inhibition(Hypertension, Basic 2 (H) : PJ30)(Poster Session (Japanese))
- PJ-152 Upregulation of endothelial plasminogen activator inhibitor-1 (PAI-1) expression by hyperglycemia through activation of apoptosis signal-regulating kinase 1 (ASK1)(Endothelium/NO 3 (H) : PJ26)(Poster Session (Japanese))
- OJ-188 Idetification of a novel apoptosis gene in cultured atherosclerotic smooth muscle cells(Atherosclerosis, Basic 2 (IHD) : OJ22)(Oral Presentation (Japanese))
- Cloning and Functional Analysis of a Novel Gene Expressed in Atherosclerotic Plaques
- Pathophysiological Remodeling of Mouse Cardiac Myocytes Expressing Dominant Negative Mutant of Neuron Restrictive Silencing Factor
- Improved long-term performance of pulsatile extracorporeal left ventricular assist device
- The combined impact of blood pressure category and glucose abnormality on the incidence of cardiovascular diseases in a Japanese urban cohort : the Suita Study
- Association of carotid atherosclerosis with genetic polymorphisms of the klotho gene in patients with hypertension
- Impact of RGS2 deficiency on the therapeutic effect of telmisartan in angiotensin II-induced aortic aneurysm
- Physical Activity and Cardiovascular Disease in Japan : The Jichi Medical School Cohort Study
- Cardiac mortality of premature ventricular complexes in healthy people in Japan
- High QRS Score on Admission Strongly Predicts Impaired Myocardial Reperfusion in Patients With a First Anterior Acute Myocardial Infarction
- Pre- and Post-Operative Risk Factors Associated With Cerebrovascular Accidents in Patients Supported by Left Ventricular Assist Device : Single Center's Experience in Japan
- Physical Activity and Risk of Fatal or Non-Fatal Cardiovascular Disease Among CVD Survivors : The JMS Cohort Study
- Studies on the genes specifically expressed in the atherosclerotic plaques of ApoE-deficient mice
- Clinical Usefulness of Additional Treatment With Ezetimibe in Patients With Coronary Artery Disease on Statin Therapy : From the Viewpoint of Cholesterol Metabolism
- The Relationship between Optimization for Cardiac Resynchronization Therapy by Measurement of dp/dt and the Middle-to-long-term Prognosis of Heart Failure Patients
- Long-term Effect of Dual-chamber Pacing on Pressure Gradient at Left Ventricular Outflow Tract in Hypertrophic Obstructive Cardiomyopathy
- Atrial Fibrillation Is a Major Risk Factor for Stroke, Especially in Women : The Jichi Medical School Cohort Study
- Clinical Outcomes Following Coronary Stenting in Japanese Patients Treated With and Without Proton Pump Inhibitor
- Differences in Negative T Waves Between Takotsubo Cardiomyopathy and Reperfused Anterior Acute Myocardial Infarction
- Guidelines for the Clinical Use of 24 Hour Ambulatory Blood Pressure Monitoring (ABPM) (JCS 2010) : Digest Version
- Guidelines for Smoking Cessation (JCS 2010) : Digest Version
- Reverse Vessel Remodeling But Not Coronary Plaque Regression Could Predict Future Cardiovascular Events in ACS Patients With Intensive Statin Therapy : The Extended JAPAN-ACS Study
- Effects of Voglibose and Nateglinide on Glycemic Status and Coronary Atherosclerosis in Early-Stage Diabetic Patients
- Influence of adrenomedullin 2/intermedin gene polymorphism on blood pressure, renal function and silent cerebrovascular lesions in Japanese : the Ohasama study
- Effects of Valsartan, an Angiotensin II Receptor Blocker, on Coronary Atherosclerosis in Patients With Acute Myocardial Infarction Who Receive an Angiotensin-Converting Enzyme Inhibitor
- Significant attenuation of macrovascular involvement by bosentan in a patient with diffuse cutaneous systemic sclerosis with multiple digital ulcers and gangrene
- Association between osteopontin promoter variants and diastolic dysfunction in hypertensive heart in the Japanese population
- The combination of chronic kidney disease and increased arterial stiffness is a predictor for stroke and cardiovascular disease in hypertensive patients
- Disrupted Regulation of Ghrelin Production Under Antihypertensive Treatment in Spontaneously Hypertensive Rats
- Development and clinical application of a new technique for detecting 'sleep blood pressure surges' in sleep apnea patients based on a variable desaturation threshold
- Frequency of Citrus Fruit Intake Is Associated With the Incidence of Cardiovascular Disease : The Jichi Medical School Cohort Study
- Efficacy of low-dose imatinib mesylate for cutaneous involvement in systemic sclerosis : a preliminary report of three cases
- Klotho protein diminishes endothelial apoptosis and senescence via a mitogen-activated kinase pathway
- A single-nucleotide polymorphism in the human THADA gene is associated with circulating resistin in the general Japanese population
- A novel Doppler echocardiographic score reflecting cardiac functional status can predict adverse outcome in acute myocardial infarction
- Significance of Coronary Vasospasm in the Perioperative Management of Non-Cardiac Surgery
- Novel Risk Scoring System With Preoperative Objective Parameters Gives a Good Prediction of 1-Year Mortality in Patients With a Left Ventricular Assist Device
- The impact of visit-to-visit variability in blood pressure on renal function
- Plasma and tissue concentrations of proangiotensin-12 in rats treated with inhibitors of the renin-angiotensin system
- Novel mechanism of angiotensin II-induced cardiac injury in hypertensive rats : the critical role of ASK1 and VEGF
- Orthostatic hypertension : home blood pressure monitoring for detection and assessment of treatment with doxazosin
- The GCKR rs780094 polymorphism is associated with susceptibility of type 2 diabetes, reduced fasting plasma glucose levels, increased triglycerides levels and lower HOMA-IR in Japanese population
- Association Between Circulating Monocytes and Coronary Plaque Progression in Patients With Acute Myocardial Infarction
- Hunting for genes for hypertension : the Millennium Genome Project for Hypertension
- Eplerenone potentiates protective effects of amlodipine against cardiovascular injury in salt-sensitive hypertensive rats