Preoperative assessment of para-aortic lymph node metastasis in patients with pancreatic cancer
スポンサーリンク
概要
- 論文の詳細を見る
BACKGROUND: Para-aortic lymph node (PALN) metastasis is an important prognostic factor in patients with pancreatic cancer, but accurate preoperative diagnosis is difficult. The objective of this study was to assess the accuracy of diagnosis of PALN by computed tomography (CT), magnetic resonance imaging (MRI), and (18)F-fluorodeoxyglucose positron-emission tomography (FDG-PET). METHODS: From August 2005 to July 2008, 119 patients with invasive ductal adenocarcinoma of the pancreas were included in this study. PALNs with a longer diameter >10 mm on CT or MRI were suspected of being involved by metastasis, whereas FDG uptake exceeding that of the adjacent normal tissue was considered to be positive for metastasis on FDG-PET studies. The imaging findings were compared with the pathological diagnosis of PALN metastasis. RESULTS: PALN dissection was performed in 71 patients (60.0%). Although histopathological examination revealed metastasis in 6 patients (8.5%), none of these patients was positive in any of the preoperative imaging studies. The longer diameter, the shorter diameter, the ratio of the two diameters, and the calculated lymph node volume showed no significant differences between patients with and without PALN metastasis. CONCLUSIONS: Preoperative detection of PALN metastasis in patients with pancreatic cancer is very difficult. Intraoperative histopathological examination of frozen sections is necessary if radical resection is contemplated.
- 2010-06-01
著者
-
TAKADA Yasutsugu
Department of Surgery, Graduate School of Medicine, Kyoto University
-
UEMOTO Shinji
Department of Surgery, Graduate School of Medicine, Kyoto University
-
DOI Ryuichiro
Department of Surgery and Surgical Basic Science, Kyoto University Graduate School of Medicine
-
Imai Hisashi
Department Of Mechanical System Engineering Toyama Prefectural University
-
Uemoto Shinji
Division Of Hepato-biliary-pancreatic Surgery And Transplantation Department Of Surgery Kyoto Univer
-
KOIZUMI Masayuki
Department of Surgery and Surgical Basic Science, Kyoto University
-
ISODA Hiroyoshi
Department of Radiology, Fujieda Municipal Hospital
-
KAWAGUCHI Yoshiya
Department of Surgery and Surgical Basic Science, Kyoto University
-
IWANAGA Yasuhiro
Department of Transplantation and Immunology, Graduate School of Medicine, Kyoto University
-
Doi Ryuichiro
Division Of Hepato-biliary-pancreatic Surgery And Transplantation Department Of Surgery Kyoto Univer
-
Doi Ryuichiro
Departments Of Hepato-biliary-pancreatic Surgery And Transplantation Kyoto University
-
MASUI Toshihiko
Department of Surgery, Fujita Health University School of Medicine
-
Koizumi Masayuki
Division Of Hepato-biliary-pancreatic Surgery And Transplantation Department Of Surgery Kyoto Univer
-
Uemoto Shinji
Department Of Hepato-biliary-pancreatic Surgery And Transplantation Kyoto University
-
Isoda Hiroyoshi
Department Of Diagnostic Imaging And Nuclear Medicine Kyoto University
-
KANAZAWA Hiroyuki
Department of Hepato-Biliary-Pancreatic Surgery and Transplantation, Kyoto University
-
KAMO Naoko
Department of Hepato-Biliary-Pancreatic Surgery and Transplantation, Kyoto University
-
Koizumi Masayuki
Department Of Hepato-biliary-pancreatic Surgery And Transplantation Kyoto University
-
Takada Yasutsugu
Department Of Hepato-biliary-pancreatic Surgery And Transplantation Kyoto University
-
Iwanaga Yasuhiro
Department Of Hepato-biliary-pancreatic Surgery And Transplantation Kyoto University
-
Doi Ryuichiro
Department Of Hepato-biliary-pancreatic Surgery And Transplantation Kyoto University
-
Doi Ryuichiro
Department Of Surgery Kyoto University
-
Doi Ryuichiro
Division Of Hepato-biliary-pancreatic Surgery And Transplantation Department Of Surgery Kyoto Univer
-
Masui Toshihiko
Department Of Hepato-biliary-pancreatic Surgery And Transplantation Kyoto University
-
Isoda Hiroyoshi
Department Of Diagnostic Imaging And Nuclear Medicine Graduate School Of Medicine
-
Manabe Toshiaki
Laboratory Of Anatomic Pathology Kyoto University Hospital Graduate School Of Medicine Kyoto Univers
-
Kawaguchi Yoshiya
Department Of Hepato-biliary-pancreatic Surgery And Transplantation Kyoto University
-
Imai Hisashi
Department Of Hepato-biliary-pancreatic Surgery And Transplantation Kyoto University
-
Kamo Naoko
Department Of Hepato-biliary-pancreatic Surgery And Transplantation Kyoto University
-
Kanazawa Hiroyuki
Department Of Hepato-biliary-pancreatic Surgery And Transplantation Kyoto University
-
Uemoto Shinji
Division Of Hepato-biliary-pancreatic Surgery And Transplantation Department Of Surgery Kyoto Univer
-
Imai Hisashi
Department Of Business Administration Yamanashi Gakuin University
-
Uemoto Shinji
Division Of Hepato-biliary-pancreatic Surgery And Transplantation Department Of Surgery Kyoto Univer
-
Koizumi Masayuki
Department of Cardiovascular Medicine, Toho University Faculty of Medicine
関連論文
- Noninvasive Ventilation Improves the Outcome of Pulmonary Complications after Liver Resection
- 成人生体肝移植症例において, ラベプラゾールの併用はタクロリムスの血中濃度推移に影響を及ぼさない
- The Impact of Total Bilirubin on Plasma Micafungin Levels in Living-Donor Liver Transplantation Recipients with Severe Liver Dysfunction(Biopharmacy)
- Tissue factor expression demonstrates severe sinusoidal endothelial cell damage during rejection after living-donor liver transplantation
- Diagnosis of pancreatic cancer using fluorine-18 fluorodeoxyglucose positron emission tomography (FDG PET) : Usefulness and limitations in "clinical reality"
- A Case of Secretin-responsive Insulinoma with Low Serum C-peptide Levels
- Analysis of E-, N-Cadherin, α-, β-, and γ-Catenin Expression in Human Pancreatic Carcinoma Cell Lines
- Surgical resection deteriorates gemcitabine-induced leukopenia in pancreatic cancer
- Pancreatic Endocrine Tumor in Japan
- Expression of Bcl-2 and PCNA in Duct Cells After Pancreatic Duct Ligation in Rats
- Detection of Matrix Metalloproteinase Activity in Human Pancreatic Cancer
- Role of Apoptosis in Duct Obstruction-Induced Pancreatic Involution in Rats
- Synthesis and Biological Activity of Bombesin Analogues Containing (E)-Alkene Dipeptide Isosteres
- Dual radionuclide single-photon emission computed tomography in the prediction of further ischemic risk after acute myocardial infarction
- Mesenchymal epimorphin is important for pancreatic duct morphogenesis
- Temporal Decline in Sirolimus Elimination Immediately After Pancreatic Islet Transplantation
- Delayed Effect of Grapefruit Juice on Pharmacokinetics and Pharmacodynamics of Tacrolimus in a Living-Donor Liver Transplant Recipient
- DIAGNOSIS OF EPSTEIN-BARR VIRUS LYMPHOMA AFTER LIVER TRANSPLANTATION
- Living-donor liver transplantation for Caroli's disease with intrahepatic adenocarcinoma
- Required Transient Dose Escalation of Tacrolimus in Living-Donor Liver Transplant Recipients with High Concentrations of a Minor Metabolite M-II in Bile
- Interaction between Tacrolimus and Lansoprazole, but not Rabeprazole in Living-Donor Liver Transplant Patients with Defects of CYP2C19 and CYP3A5
- Subclinical central pontine myelinolysis following liver transplantation
- Lens culinaris agglutinin-A-reactive alpha-fetoprotein as a marker for liver atrophy in fulminant hepatic failure
- Circulating antibody to hepatitis B core antigen does NOT always reflect the latent hepatitis B virus infection in the liver tissue
- Successful Surgical Ligation Under Intraoperative Portal Vein Pressure Monitoring of a Large Portosystemic Shunt Presenting as an Intrapulmonary Shunt : Report of a Case
- Impact of Enteral Nutrition in Adult-to-Adult Living Donor Liver Transplantation : A Preliminary Study
- Surgery Versus Radiochemotherapy for Resectable Locally Invasive Pancreatic Cancer : Final Results of a Randomized Multi-Institutional Trial
- Analysis of regulatory T cells and IgG4-positive plasma cells among patients of IgG4-related sclerosing cholangitis and autoimmune liver diseases
- Prophylactic Respiratory Management After Liver Resection with Bilevel Positive Airway Pressure Ventilation : Report of Three Cases
- Hemolytic Reaction Due to Graft-Versus-Host (GVH) Antibody Production After Liver Transplantation from Living Donors : Report of Two Cases
- Loss of heterozygosity on 10q23 is involved in metastatic recurrence of hepatocellular carcinoma
- POSTOPERATIVE MANAGEMENT BASED ON REDOX THEORY IN LIVING RELATED LIVER TARNSPLANTATION IN CHILDREN(International Symposium ,第29回日本小児外科学会総会)
- Orotate phosphoribosyltransferase levels measured by a newly established enzyme-linked immunosorbent assay in gastric carcinoma
- Expression and Function of the Calcium-Sensing Receptor in Pancreatic Islets and Insulinoma Cells
- Idiopathic calcifying pancreatitis in a Japanese pediatric patient
- Large-animal models of fulminant hepatic failure
- Mechanical Properties of a Titanium Matrix Composite Reinforced with Low Cost Carbon Black via Powder Metallurgy Processing
- Histological recurrence of autoimmune liver diseases after living-donor liver transplantation
- タクロリムス併用の膵島移植患者では, 同一血中濃度に維持するためにシロリムスに比べてエベロリムスでより多くの投与量を必要とする
- Expression of OATP1B3 determines uptake of Gd-EOB-DTPA in hepatocellular carcinoma
- Treatment of Locally Advanced Pancreatic Cancer : Should We Resect When Resectable?
- Depletion of CD4^+CD25^+ regulatory T cells enhances interleukin-2-induced antitumor immunity in a mouse model of colon adenocarcinoma
- Epidemiological study of gastroenteropancreatic neuroendocrine tumors in Japan
- Preoperative assessment of para-aortic lymph node metastasis in patients with pancreatic cancer
- Single-institution validation of the international consensus guidelines for treatment of branch duct intraductal papillary mucinous neoplasms of the pancreas
- Direct Welding of Metals and Ceramics by Ultrasonic Vibration
- Reply to the letter by Y. Ni et al. regarding "Expression of OATP1B3"
- False Positive Blood Tacrolimus Concentration in Microparticle Enzyme Immunoassay
- Epimorphin in embryonic pancreas induces epithelial morphogenesis(The 105th Annual Congress of Japan Surgical Society)
- Recent progress in management of duodenal-pancreatic endocrine tumors
- Pancreatic Lesions in von Hippel-Lindau Syndrome : The Coexistence of Metastatic Tumors from Renal Cell Carcinoma and Multiple Cysts
- Apoptosis of acinar cells in rat pancreatic duct ligation
- Effect of a New Bombesin Receptor Antagonist, (E)-Alkene Bombesin Isostere, on Amylase Release from Rat Pancreatic Acini
- Xanthogranulomatous Cholecystitis Complicated with Primary Sclerosing Cholangitis : Report of a Case
- Finding the Optimum Parameters for Ultrasonic Welding of Aluminum Alloys(Recent Advances in Materials and Processing (I))
- First Case Report of Acquired Pure Red Cell Aplasia Associated with Micafungin
- In-111 Labeled Leukocyte Scintigraphy in Patients with Suspected Inflammation after Faailed Antibody Therapy
- Abdominal Wall Recurrence of Hilar Bile Duct Cancer 12 Years After a Curative Resection : Report of a Case
- Contribution of ^F-fluorodeoxyglucose positron emission tomography to the diagnosis of early pancreatic carcinoma
- Utility of Plasma Bioactive Peptides Levels as Biomarkers
- Rapid and aggressive recurrence accompanied by portal tumor thrombus after radiofrequency ablation for hepatocellular carcinoma
- A comparative study of pathological staging systems in predicting recurrent hepatocellular carcinoma after liver transplantation
- Perfusion CT is superior to angiography in predicting pancreatic necrosis in patients with severe acute pancreatitis.
- Noninvasive Intraductal Papillary Mucinous Neoplasm with Para-Aortic Lymph Node Metastasis : Report of a Case
- Muromonab-CD3 therapy for refractory rejections after liver transplantation : a single-center experience during two decades in Japan
- Liver transplantation for hepatocellular carcinoma : the Kyoto experience
- Successful Left Hemihepatectomy and Perioperative Management of a Patient with Biliary Cystadenocarcinoma, Complicated with MELAS Syndrome : Report of a Case
- A large cystic gastrointestinal stromal tumor of the rectum in the retrorectal space
- Prognostic value of ^F-fluorodeoxyglucose positron emission tomography in patients with extrahepatic bile duct cancer
- Genetic lineage tracing, a powerful tool to investigate the embryonic organogenesis and adult organ maintenance of the pancreas
- 627 Ultrasonic welding of ceramics and metals
- Muromonab-CD3 for the Successful Treatment of Early Chronic Rejection After Pediatric Liver Transplantation : Report of a Case
- Management of ABO-Incompatible Living-Donor Liver Transplantation : Past and Present Trends
- The distribution of atypical epithelium in main-duct type intraductal papillary mucinous neoplasms of the pancreas
- Predictive risk factors for clinically relevant pancreatic fistula analyzed in 1,239 patients with pancreaticoduodenectomy : multicenter data collection as a project study of pancreatic surgery by the Japanese Society of Hepato-Biliary-Pancreatic Surgery
- Loss of RUNX3 expression by histone deacetylation is associated with biliary tract carcinogenesis
- Early impact of depression symptoms on the decline in activities of daily living among older Japanese : Y-HALE cohort study
- A nomogram predicting disease-free survival in patients with colorectal liver metastases treated with hepatic resection : multicenter data collection as a Project Study for Hepatic Surgery of the Japanese Society of Hepato-Biliary-Pancreatic Surgery
- Delayed gastric emptying improved by straight stomach reconstruction with twisted anastomosis to the jejunum after pylorus-preserving pancreaticoduodenectomy (PPPD) in 118 consecutive patients at a single institution
- Early evaluation of transcatheter arterial chemoembolization-refractory hepatocellular carcinoma
- Errata: The Impact of Total Bilirubin on Plasma Micafungin Levels in Living-Donor Liver Transplantation Recipients with Severe Liver Dysfunction [Biol. Pharm. Bull. 32(4): 750-754 (2009)]
- Effectiveness of sirolimus in combination with cyclosporine against chronic rejection in a pediatric liver transplant patient
- Activation of Aryl Hydrocarbon Receptor Mediates Indoxyl Sulfate-Induced Monocyte Chemoattractant Protein-1 Expression in Human Umbilical Vein Endothelial Cells
- Living-donor liver transplantation for moderate or severe porto-pulmonary hypertension accompanied by pulmonary arterial hypertension : a single-centre experience over 2 decades in Japan
- Bifid Tail of the Pancreas with Localized Acute Pancreatitis
- Influence of Cytochrome P450 (CYP) 3A4*1G Polymorphism on the Pharmacokinetics of Tacrolimus, Probability of Acute Cellular Rejection, and mRNA Expression Level of CYP3A5 Rather than CYP3A4 in Living-Donor Liver Transplant Patients
- Successful telaprevir treatment in combination of cyclosporine against recurrence of hepatitis C in the Japanese liver transplant patients
- Factors Explaining Disability-free Life Expectancy in Japan: the Proportion of Older Workers, Self-reported Health Status, and the Number of Public Health Nurses
- EXPERIENCES OF TREATMENT WITH PAVLIK'S BANDAGE FOR CONGENITAL DISLOCATION OF THE HIP IN INFANTS
- Comparative study of cisplatin and epirubicin in transcatheter arterial chemoembolization for hepatocellular carcinoma
- Living donor liver transplantation for hepatitis C
- Disease recurrence plays a minor role as a cause for retransplantation after living-donor liver transplantation for primary biliary cirrhosis : A multicenter study in Japan
- Aryl Hydrocarbon Receptor Mediates Indoxyl Sulfate-Induced Cellular Senescence in Human Umbilical Vein Endothelial Cells